Sivelestat relieves respiratory distress refractory to dexamethasone in all-trans retinoic acid syndrome: A report of two cases

European Journal of Haematology

Volumn 77, Issue 5, 2006, Pages 448-452

  Kawasaki, Kozo ^a   Akaike, Hiroto ^a   Miyauchi, Ayaka ^a   Ouchi, Kazunobu ^a  

^a KAWASAKI MEDICAL SCHOOL   (Japan)

Author keywords

Acute lung injury; Acute promyelocytic leukemia; All trans retinoic acid; Elastase inhibitor; Neutrophil elastase; Respiratory distress

Indexed keywords

ANTHRACYCLINE; CIMETIDINE; CYTARABINE; DAUNORUBICIN; DEXAMETHASONE; GABEXATE MESILATE; LEUKOCYTE ELASTASE INHIBITOR; MANNITOL; RETINOIC ACID; SIVELESTAT;

ACUTE GRANULOCYTIC LEUKEMIA; ADOLESCENT; ARTICLE; BLOOD TRANSFUSION; BRAIN DYSFUNCTION; BRAIN EDEMA; BRAIN HEMORRHAGE; CANCER COMBINATION CHEMOTHERAPY; CANCER REGRESSION; CASE REPORT; CAUSE OF DEATH; DRUG TREATMENT FAILURE; DRUG WITHDRAWAL; FEMALE; GENE REARRANGEMENT; HEMATOLOGICAL PARAMETERS; HUMAN; LUNG ASPIRATION; LUNG HEMORRHAGE; MALE; OXYGEN SATURATION; OXYGENATION; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA; RESPIRATORY DISTRESS; RETINOIC ACID SYNDROME; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCHOOL CHILD; THORAX RADIOGRAPHY; TREATMENT OUTCOME;

ANTHRACYCLINES; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CYTARABINE; CYTOPROTECTION; DEXAMETHASONE; FEMALE; GLYCINE; HUMANS; INTRACRANIAL HEMORRHAGES; LEUKEMIA, PROMYELOCYTIC, ACUTE; MALE; PROSPECTIVE STUDIES; RANDOMIZED CONTROLLED TRIALS; RANDOMIZED CONTROLLED TRIALS AS TOPIC; REMISSION INDUCTION; RESPIRATORY DISTRESS SYNDROME, ADULT; SERINE PROTEINASE INHIBITORS; SULFONAMIDES; TRETINOIN;

EID: 33749261621     PISSN: 09024441     EISSN: 16000609     Source Type: Journal    
DOI: 10.1111/j.0902-4441.2006.t01-1-EJH2852.x     Document Type: Article

References (14)

1. DE BOTTON S, COITEUX V, CHEVRET S, et al. Outcome of childhood acute promyelocytic leukemia with all-transretinoic acid and chemotherapy. J Clin Oncol 2004;22:1404-1412.
2. DE BOTTON S, DOMBRET H, SANZ M, et al. Incidence, clinical features, and outcome of all trans-retinoic acid syndrome in 413 cases of newly diagnosed acute promyelocytic leukemia. The European APL Group. Blood 1998;92:2712-2718.
3. TALLMAN MS, ANDERSEN JW, SCHIFFER CA, et al. Clinical description of 44 patients with acute promyelocytic leukemia who developed the retinoic acid syndrome. Blood 2000;95:90-95.
4. WARE LB, MATTHAY MA. The acute respiratory distress syndrome. N Engl J Med 2000;342:1334-1349.
5. JUNG JI, CHOI JE, HAHN ST, MIN CK, KIM CC, PARK SH. Radiologic features of all-trans-retinoic acid syndrome. Am J Roentgenol 2002;178:475-480.
6. NICOLLS MR, TERADA LS, TUDER RM, PRINDIVILLE SA, SCHWARZ MI. Diffuse alveolar hemorrhage with underlying pulmonary capillaritis in the retinoic acid syndrome. Am J Respir Crit Care Med 1998;158:1302-1305.
7. RAANANI P, SEGAL E, LEVI I, BERCOWICZ M, BERKENSTAT H, AVIGDOR A, PEREL A, BEN-BASSAT I. Diffuse alveolar hemorrhage in acute promyelocytic leukemia patients treated with ATRA - a manifestation of the basic disease or the treatment. Leuk Lymphoma 2000;37:605-610.
8. MAHENDRA P, HARMAN K, PHILLIPS M, GUNNING K, MARCUS RE. Rapid progression of 'retinoic acid syndrome' in the hypogranular variant of acute promyelocytic leukaemia, despite treatment with dexamethasone and conventional chemotherapy. Clin Lab Haematol 1994;16:371-374.
9. MORAES TJ, CHOW CW, DOWNEY GP. Proteases and lung injury. Crit Care Med 2003;31:S189-S194.
10. TAMAKUMA S, OGAWA M, AIKAWA N, et al. Relationship between neutrophil elastase and acute lung injury in humans. Pulm Pharmacol Ther 2004;17:271-279.
11. ZEIHER BG, ARTIGAS A, VINCENT JL, DMITRIENKO A, JACKSON K, THOMPSON BT, BERNARD G; STRIVE Study Group. Neutrophil elastase inhibition in acute lung injury: results of the STRIVE study. Crit Care Med 2004;32:1695-1702.
12. GUO L, YAMAGUCHI Y, IKEI S, SUGITA H, OGAWA M. Neutrophil elastase inhibitor (ONO-5046) prevents lung hemorrhage induced by lipopolysaccharide in rat model of cerulein pancreatitis. Dig Dis Sci 1995;40:2177-2183.
13. RODEGHIERO F, AVVISATI G, CASTAMAN G, BARBUI T, MANDELLI F. Early deaths and anti-hemorrhagic treatments in acute promyelocytic leukemia. A GIMEMA retrospective study in 268 consecutive patients. Blood 1990;75:2112-2117.
14. UMEKI S, ADACHI M, WATANABE M, YAJI S, SOEJIMA R. Gabexate as a therapy for disseminated intravascular coagulation. Arch Intern Med 1988;148:1409-1412.