A small scale oxygenator for cardiopulmonary bypass in rats

International Journal of Artificial Organs

Volumn 29, Issue 8, 2006, Pages 750-755

  Ordodi, V L ^a   Paunescu, V ^a   Mic, A A ^a   Ionac, M ^a   Sandesc, D ^a   Mic, Felix A ^b,c  

^a VICTOR BABES UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

^b Performa Diagnostics SRL   (Romania)

^c Clinical Emergency County Hospital Pius Brinzeu Timisoara   (Romania)

Author keywords

Artificial organ; Cardiopulmonary bypass; Heart; Lung; Oxygenation; Oxygenator blood; Rat

Indexed keywords

BLOOD; CYLINDERS (SHAPES); OXYGEN; OXYGENATORS; RATS; RESPIRATORY THERAPY;

BLOOD OXYGENATION; CARDIOPULMONARY BYPASS; OXYGEN TRANSFER; OXYGENATOR BLOOD; PHYSIOLOGICAL LEVELS; PULMONARY EDEMA; SIMPLE++; SMALL SCALE; THIN LAYERS; VERTICAL CYLINDERS;

OXYGENATION;

OXYGEN;

AIR; ANIMAL EXPERIMENT; ARTERIAL PRESSURE; ARTICLE; BLOOD OXYGEN TENSION; BLOOD OXYGENATION; BLOOD PUMP; CARDIOPULMONARY BYPASS; CONTROLLED STUDY; EQUIPMENT DESIGN; EXPERIMENTAL ANIMAL; GAS ANALYSIS; NONHUMAN; OXYGENATOR; QUANTITATIVE ANALYSIS; RAT; RAT STRAIN; RESERVOIR; STATISTICAL ANALYSIS;

EID: 33749256784     PISSN: 03913988     EISSN: None     Source Type: Journal    
DOI: 10.1177/039139880602900804     Document Type: Article

References (21)

1. Dorson WJ Jr, Larsen KG, Elgas RJ, Voorhees ME. Oxygen transfer to blood: Data and theory. Trans Am Soc Artif Intern Organs 1971; 17: 309-16.
2. Voorhees ME, Brian BF 3rd. Blood-gas exchange devices. Int Anesthesiol Clin 1996; 34: 29-45.
3. Voorhees ME. Oxygenator technology: The future. Perfusion 1994; 9: 229-32.
4. Wegner JA. Oxygenator anatomy and function. J Cardiothorac Vasc Anesth 1997; 11: 275-81.
5. Palanzo DA. Perfusion safety: Past, present, and future. J Cardiothorac Vasc Anesth 1997; 11: 383-90.
6. Mackensen GB, Sato Y, Nellgard B, Pineda J, Newman MF, Warner DS, Grocott HP. Cardiopulmonary bypass induces neurologic and neurocognitive dysfunction in the rat. Anesthesiology 2001; 95: 1485-91.
7. Levy JH, Tanaka KA. Inflammatory response to cardiopulmonary bypass. Ann Thorac Surg 2003; 75 (suppl): S715-20.
8. Sasaki S, Takigami K, Shiiya N, Yasuda K. Partial cardiopulmonary bypass in rats for evaluating ischemia-reperfusion injury. ASAIO J 1996; 42: 1027-30.
9. Gibbon JH Jr. Application of a mechanical heart and lung apparatus to cardiac surgery. Minn Med 1954; 37: 171-85.
10. Alexander B, Al Ani HR. Prolonged partial cardiopulmonary bypass in rats. J Surg Res 1983; 35: 28-34.
11. Subramanian V, McLeod J, Gans H. Effect of extracorporeal circulation on reticuloendothelial function. I. Experimental evidence for impaired reticuloendothelial function following cardiopulmonary bypass in rats. Surgery 1968; 64: 775-84.
12. Proctor E. An oxygenator for cardiopulmonary bypass in the rat. J Surg Res 1977; 22: 124-7.
13. Triggiani E, Coppola M, Nigro R, Napoli V, Bellini O. Extracorporeal circulation in the rat. Technical aspects. Boll Soc Ital Biol Sper 1970; 46: 998-1001.
14. Popovic P, Horecky J, Popovic VP. Hypothermic cardiopulmonary bypass in white rats. Ann Surg 1968; 168: 298-301.
15. Siderys H, Herod GT, Halbrook H, Pittman JN, Rubush JL, Kasebaker V, Berry GR Jr. A comparison of membrane and bubble oxygenation as used in cardiopulmonary bypass in patients. The importance of pericardial blood as a source of hemolysis. J Thorac Cardiovasc Surg 1975; 69: 708-12.
16. Fabre O, Zegdi R, Vincentelli A, Cambillaud M, Prat A, Carpentier A, Fabiani JN.A recovery model of partial cardiopulmonary bypass in the rat. Perfusion 2001; 16: 215-20.
17. Moehrlen U, Stammberger U, Moehrlen C, Schmid RA. Partial cardiopulmonary bypass in rats using a hollow fibre oxygenator. Interactive Cardiovascular and Thoracic Surgery 2003; 2: 603-6.
18. Dong GH, Xu B, Wang CT, Qian JJ, Liu H, Huang G, Jing H. A rat model of cardiopulmonary bypass with excellent survival. J Surg Res 2005; 123: 171-5.
19. Gourlay T, Ballaux PK, Draper ER, Taylor KM. Early experience with a new technique and technology designed for the study of pulsatile cardiopulmonary bypass in the rat. Perfusion 2002; 17: 191-8.
20. You XM, Nasrallah F, Darling E, Robins M, Nieman G, Searles B. Rat cardiopulmonary bypass model: Application of a miniature extracorporeal circuit composed of asanguinous prime. J Extra Corpor Technol 2005; 37: 60-5.
21. Ordodi VL, Mic FA, Mic AA, Sandesc D, Paunescu V. A simple device for invasive measurement of arterial blood pressure and ECG in the anesthesized rat. Timisoara Medical Journal (in press).