Comparison of extracellular and intracellular potency of botulinum neurotoxins

Infection and Immunity

Volumn 74, Issue 10, 2006, Pages 5617-5624

  Cai, Fang ^a   Adrion, Carrie B ^a   Keller, James E ^a  

^a CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BOTULINUM TOXIN; BOTULINUM TOXIN A; BOTULINUM TOXIN E; EDETIC ACID; ETHYLENEDIAMINE DERIVATIVE; N,N,N'',N' TETRAKIS(2 PYRIDYLMETHYL)ETHYLENEDIAMINE; SYNAPTOSOMAL ASSOCIATED PROTEIN 25; UNCLASSIFIED DRUG; ZINC;

ANIMAL CELL; ARTICLE; BOTULISM; CELL FREE SYSTEM; CHELATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVITY; EXTRACELLULAR SPACE; HEAVY METAL REMOVAL; IN VITRO STUDY; INCUBATION TIME; INTRACELLULAR TRANSPORT; MEMBRANE PERMEABILITY; METAL BINDING; MOUSE; NERVE CELL CULTURE; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DEGRADATION; PROTEIN DOMAIN; REGULATORY MECHANISM; SERODIAGNOSIS; SEROTYPING; SPECIES COMPARISON; STRUCTURE ACTIVITY RELATION;

ANIMALS; BIOLOGICAL ASSAY; BOTULINUM TOXIN TYPE A; BOTULINUM TOXINS; BOTULINUM TOXINS, TYPE A; CELLS, CULTURED; CHELATING AGENTS; EDETIC ACID; ETHYLENEDIAMINES; MICE; MICE, INBRED C57BL; NEURONS; NEUROTOXINS; PEPTIDE HYDROLASES; ZINC;

EID: 33749250406     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.00552-06     Document Type: Article

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