Increased mortality among elderly patients with meticillin-resistant Staphylococcus aureus bacteraemia

Journal of Hospital Infection

Volumn 64, Issue 3, 2006, Pages 251-256

  Tacconelli, E ^a   Pop Vicas, A E ^a   D'Agata, E M C ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Bloodstream infection; Elderly; Meticillin resistance; Outcomes; Staphylococcus aureus

Indexed keywords

VANCOMYCIN;

ADULT; AGE DISTRIBUTION; AGED; ANTIBIOTIC THERAPY; ARTICLE; BACTEREMIA; BACTERIAL TRANSMISSION; CASE CONTROL STUDY; CATHETER INFECTION; COMORBIDITY; CONFIDENCE INTERVAL; CONTROLLED STUDY; DEATH; DISEASE SEVERITY; DRUG DOSE REDUCTION; FEMALE; GERIATRIC PATIENT; HOSPITAL ADMISSION; HOSPITAL BED; HOSPITALIZATION; HUMAN; INFECTION PREVENTION; KIDNEY FAILURE; LOGISTIC REGRESSION ANALYSIS; LUNG INFECTION; MAJOR CLINICAL STUDY; MALE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MORTALITY; NONHUMAN; OUTCOME ASSESSMENT; STATISTICAL SIGNIFICANCE; TEACHING HOSPITAL; WARD;

AGED; AGED, 80 AND OVER; BACTEREMIA; CROSS INFECTION; FEMALE; HUMANS; MALE; METHICILLIN RESISTANCE; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS;

EID: 33749246245     PISSN: 01956701     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhin.2006.07.001     Document Type: Article

References (29)

1. Kuehnert M.J., Hill H.A., Kupronis B.A., et al. Methicillin-resistant Staphylococcus aureus hospitalizations, United States. Emerg Infect Dis 11 (2005) 868-872
2. Diekema D.J., Pfaller M.A., Jones R.N., and SENTRY Participants Group. Age-related trends in pathogen frequency and antimicrobial susceptibility of bloodstream isolates in North America. Int J Antimicrob Agents 20 (2002) 4142-4148
3. Cosgrove S.E., Qi Y., Kaye K.S., et al. The impact of methicillin resistance in Staphylococcus aureus bacteremia on patient outcomes: mortality, length of stay, and hospital charges. Infect Control Hosp Epidemiol 26 (2005) 166-174
4. Kopp B.J., Nix D.E., and Armstrong E.P. Clinical and economic analysis of methicillin-susceptible and -resistant Staphylococcus aureus infections. Ann Pharmacother 38 (2004) 1377-1382
5. Cosgrove S.E., Sakoulas G., Perencevich E.N., et al. Comparison of mortality associated with methicillin-resistant and methicillin-susceptible Staphylococcus aureus bacteremia: a meta-analysis. Clin Infect Dis 36 (2003) 53-59
6. High K. Infection as a cause of age-related morbidity and mortality. Ageing Res Rev 3 (2004) 1-14
7. Charlson M., Pompei P., Ales K., et al. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 40 (1987) 373-383
8. McCabe W., and Jackson G. Gram-negative bacteremia. Arch Intern Med 110 (1962) 847-888
9. Garner J.S., Jarvis W.R., Emori T.G., et al. CDC definitions for nosocomial infections. Am J Infect Control 16 (1988) 128-140
10. Durack D.T., Lukes A.S., and Bright D.K. New criteria for diagnosis of infective endocarditis: utilization of specific echocardiographic findings. Duke Endocarditis Service. Am J Med 96 (1994) 200-209
11. Murray P.R., Barron E.J., and Pfaller M.A. Manual of clinical microbiology. 7th ed. (1998), American Society for Microbiology, Washington DC
12. National Committee for Clinical Laboratory Standards. Performance standards for antimicrobial disk susceptibility tests: approved standard M2-A6 (1997), NCCLS, Villanova, PA
13. Nicolle L.E., Strausbaugh L.J., and Garibaldi R.A. Infections and antibiotic resistance in nursing homes. Clin Microbiol Rev 9 (1995) 1-17
14. Mylotte J.M., Goodnough S., and Tayara A. Antibiotic-resistant bacteria in long-term care facility residents on admission to an inpatient geriatrics unit: retrospective and prospective surveillance. Am J Infect Control 29 (2001) 139-144
15. Lucet J.C., Grenet K., Armand-Lefevre L., et al. High prevalence of carriage of methicillin-resistant Staphylococcus aureus at hospital admission in elderly patients: implications for infection control strategies. Infect Control Hosp Epidemiol 26 (2005) 121-126
16. Cretnik T.Z., Vovko P., Retelj M., et al. Prevalence and nosocomial spread of methicillin-resistant Staphylococcus aureus in a long-term-care facility in Slovenia. Infect Control Hosp Epidemiol 26 (2005) 184-190
17. O'Sullivan N.R., and Keane C.T. The prevalence of methicillin-resistant Staphylococcus aureus among the residents of six nursing homes for the elderly. J Hosp Infect 34 (2000) 206-210
18. Muder R.R., Brennen C., Wageneer M.M., et al. Bacteremia in a long-term care facility: a five-year prospective study of 163 consecutive episodes. Clin Infect Dis 14 (1992) 647-654
19. Setia U., Serventi I., and Lorenz P. Bacteremia in a long-term care facility: spectrum and mortality. Arch Intern Med 144 (1984) 1633-1635
20. Jernigan J.A., Pullen A.L., Flowers L., et al. Prevalence of and risk factors for colonization with methicillin-resistant Staphylococcus aureus at the time of hospital admission. Infect Control Hosp Epidemiol 24 (2003) 409-414
21. McHugh C.G., and Riley L.W. Risk factors and costs associated with methicillin-resistant Staphylococcus aureus bloodstream infections. Infect Control Hosp Epidemiol 25 (2004) 425-430
22. Vovko P., Retelj M., Cretnik T.Z., et al. Risk factors for colonization with methicillin-resistant Staphylococcus aureus in long-term-care facilities in Slovenia. Infect Control Hosp Epidemiol 26 (2005) 191-195
23. Simor A.E., Ofner-Agostini M., Paton S., et al. Clinical and epidemiological features of methicillin-resistant Staphylococcus aureus in elderly hospitalized patients. Infect Control Hosp Epidemiol 26 (2005) 838-840
24. Jensen A.G., Wachmann C.H., Espersen F., et al. Treatment and outcome of Staphylococcus aureus bacteremia: a prospective study of 278 cases. Arch Intern Med 162 (2002) 25-32
25. Laupland K.B., Church D.L., Mucenski M., et al. Population-based study of the epidemiology of and the risk factors for invasive Staphylococcus aureus infections. J Infect Dis 187 (2003) 1452-1459
26. Fowler Jr. V.G., Justice A., Moore C., et al. Risk factors for hematogenous complications of intravascular catheter-associated Staphylococcus aureus bacteremia. Clin Infect Dis 40 (2005) 695-703
27. Campion E.W. The oldest old. N Engl J Med 330 (1995) 1819-1820
28. Capitano B., Leshem O.A., Nightingale C.H., et al. Cost effect of managing methicillin-resistant Staphylococcus aureus in a long-term care facility. J Am Geriatr Soc 51 (2003) 10-16
29. Correa L., and Pittet D. Problems and solutions in hospital-acquired bacteraemia. J Hosp Infect 46 (2000) 89-95