Age does not affect airway pH and ammonia as determined by exhaled breath measurements

Lung

Volumn 184, Issue 4, 2006, Pages 195-200

  Brooks, Stuart M ^a,b   Haight, Robert R ^a   Gordon, Robert L ^a  

^a NATIONAL SCHOOL OF PUBLIC HEALTH   (United States)

^b UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

Aging; Airway pH; Breath tests

Indexed keywords

AMMONIA;

ADULT; AGED; AGING; ARTICLE; CONTROLLED STUDY; EXPIRED AIR; FEMALE; HUMAN; HUMAN EXPERIMENT; MALE; PH MEASUREMENT; POPULATION; PRIORITY JOURNAL; SPIROMETRY;

ADOLESCENT; ADULT; AGE FACTORS; AGED; AMMONIA; BREATH TESTS; EXHALATION; FEMALE; HUMANS; HYDROGEN-ION CONCENTRATION; MALE; MIDDLE AGED; RESPIRATORY SYSTEM;

EID: 33749180143     PISSN: 03412040     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00408-005-2580-1     Document Type: Article

References (23)

1. Aicken M, Glensler H (1996) Adjusting for multiple testing when reporting research results: The Bonferroni vs. Holm methods. Am J Public Health Care Med 86:726-728
2. American Thoracic Society (1994) Standardization of spirometry: 1994 update. ATS Statement. Am J Respir Crit Care Med 152:1107-1136
3. Borrill Z, Starkey C, Vestbo J, Singh D (2005) Reproducibility of exhaled breath condensate pH in chronic obstructive pulmonary disease. Eur Respir J 25:269-274
4. Effros RM (2001) Endogenous airway acidification: implications for asthma pathology [letter]. Am J Respir Crit Care Med 163:293-294
5. Effros RM (2003) Do low exhaled condensate NH4+ concentrations in asthma reflect reduced pulmonary production? [letter]. Am J Respir Crit Care Med 167:91-92
6. Effros RM, Dunning MB, Biller J, Shaker R (2004) The promise and perils of exhaled breath condensates. Am J Physiol Cell Physiol 287:L1073-L1080
7. Fischer H, Widdicombe JH, Illek B (2002) Acid secretion and proton conductance in human airway epithelium. Am J Physiol Cell Physiol 282:C736-C743
8. Gaston BM, Hunt JF (2003) Do low exhaled condensate NH4+ concentrations in asthma reflect reduced pulmonary production? [letter]. Am J Physiol Respir Crit Care Med 167:91-92
9. Hankinson JL, Odencrantz JR, Fedan KB (1999) Spirometric reference values from a sample of the general U.S. population. Am J Respir Crit Care Med 159:179-187
10. Hug MJ, Tamada T, Bridges RJ (2003) CFTR and bicarbonate secretion to epithelial cells. New Physiol Sci 18:38-42
11. Hunt JF, Fang K, Malik R, et al. (2000) Endogenous airway acidification: implications for asthma pathophysiology. Am J Respir Crit Care Med 161:694-699
12. Hunt JF, Palmer L, Vaughan J (2002) Expressin and activity of pH-regulatory glutaminase in the human airway epithelium. Am J Respir Crit Care Med 165:101-107
13. Jayaraman S, Song Y, Verkman AS (2001) Airway surface liquid pH in well-differentiated airway epithelial cell cultures and mouse trachea. Am J Physiol Cell Physiol 281:C1504-C1511
14. Kharitonov SA, Barnes P (2001) Exhaled markers of pulmonary disease. Am J Respir Crit Care Med 163:1693-1722
15. Kostikas K, Papatheodorou G, Ganas K, et al. (2002) pH in expired breath condensate of patients with inflammatory airway diseases. Am J Respir Crit Care Med 165:1364-1370
16. McCafferty JB, Bradshaw TA, Tate S, Greening AP, Innes JA (2004) Effects of breathing pattern and inspired air conditions on breath condensate volume, pH, nitrite and protein concentrations. Thorax 59:694-698
17. Nimi A, Nguyen LT, Usmani O, Mann B, Chung MF (2004) Reducd pH and chloride levels in exhaled breath condensate of patients with chronic cough. Throax 59:608-612
18. Poulsen JH, Fischer H, Illek B, Machen TE (1994) Bicarbonate conductance and pH regulatory capability of cystic fibrosis transmembrane conductance regulator. Proc Natl Acad Sci USA 91:5340-5344
19. Ricciardolo FLM, Gaston B, Hunt J (2004) Acid stress in the pathology of asthma. J Allergy Clin Immunol 13:610-619
20. Tate S, MacGregor G, Davis M, Innes JA, Greening AP (2005) Airways in cystic fibrosis are acidified: detection by exhaled breath condensate. Thorax 57:926-929
21. Vass G, Huszar E, Barat E, et al. (2003) Comparison of nasal and oral inhalation during exhaled breath condensate collection. Am J Respir Crit Care Med 67:850-855
22. Vaughan J, Ngamtrakulpanit L, Pajewski TN, et al. (2003) Exhaled breath condensate pH is a robust and reproducible assay of airway acidity. Eur Respir J 22:889-894
23. Wells K, Vaughan J, Pajewski TN, et al. (2003) Exhaled breath condensate pH assay are not influenced by oral ammonia. Thorax 60:27-31