Synthesis of enantiopure pyrrolidine-derived peptidomimetics and oligo-β-peptides via nucleophilic ring-opening of β-lactams

Journal of Organic Chemistry

Volumn 71, Issue 20, 2006, Pages 7721-7730

  Macías, Alberto ^a   Ramallal, Antonio Morán ^a   Alonso, Eduardo ^a   Del Pozo, Carlos ^b   González, Javier ^a  

^a UNIVERSITY OF OVIEDO   (Spain)

^b UNIVERSITY OF VALENCIA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CONFORMATIONS; MATHEMATICAL MODELS; MOLECULAR STRUCTURE; NITROGEN COMPOUNDS; NUCLEAR MAGNETIC RESONANCE; STEREOCHEMISTRY; SYNTHESIS (CHEMICAL);

BIOLOGICAL ACTIVITY; ENANTIOMERS; MELANOSTATIN; PEPTIDOMIMETICS;

POLYPEPTIDES;

BETA LACTAM DERIVATIVE; MELANOSTATIN; OLIGOPEPTIDE; PHENYLALANINE DERIVATIVE; PYRROLIDINE DERIVATIVE; SPIRO COMPOUND;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CYCLOADDITION; DRUG CONFORMATION; DRUG SYNTHESIS; ENANTIOMER; NUCLEAR OVERHAUSER EFFECT; PROTON NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS; RING OPENING; THEORETICAL MODEL; THEORETICAL STUDY;

BETA-LACTAMS; DRUG DESIGN; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR MIMICRY; MSH RELEASE-INHIBITING HORMONE; OLIGOPEPTIDES; PYRROLIDINES; STEREOISOMERISM;

EID: 33749176923     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo061189l     Document Type: Article

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