Rationale and protocol of a trial for prevention of diabetic atherosclerosis by using antiplatelet drugs: Study of Diabetic Atherosclerosis Prevention by Cilostazol (DAPC study)

Cardiovascular Diabetology

Volumn 5, Issue , 2006, Pages

  Yamasaki, Yoshimitsu ^a   Kim, Young Seol ^b   Kawamori, Ryuzo ^c  

^a OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

^b Kyung Hee University Hospital   (South Korea)

^c JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ANTITHROMBOCYTIC AGENT; CILOSTAZOL;

ACUTE HEART INFARCTION; ADULT; AGED; ANGINA PECTORIS; ANKLE BRACHIAL INDEX; ANTICOAGULANT THERAPY; ARTERY INTIMA PROLIFERATION; ARTICLE; ASIA; ATHEROSCLEROSIS; BRAIN ATHEROSCLEROSIS; BRAIN INFARCTION; CARDIOVASCULAR DISEASE; CLINICAL PROTOCOL; CLINICAL TRIAL; COMMON CAROTID ARTERY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DATA COLLECTION METHOD; DIABETIC ANGIOPATHY; DISEASE COURSE; DOSE RESPONSE; DRUG EFFICACY; DRUG SAFETY; DRUG WITHDRAWAL; FOLLOW UP; HUMAN; INTERNAL CAROTID ARTERY; MAJOR CLINICAL STUDY; MORTALITY; NON INSULIN DEPENDENT DIABETES MELLITUS; NUCLEAR MAGNETIC RESONANCE IMAGING; ONLINE SYSTEM; OUTCOMES RESEARCH; PERIPHERAL OCCLUSIVE ARTERY DISEASE; PRIMARY PREVENTION; PROSPECTIVE STUDY; QUANTITATIVE ANALYSIS; RANDOMIZED CONTROLLED TRIAL; STROKE; SUDDEN DEATH; TRANSIENT ISCHEMIC ATTACK;

ATHEROSCLEROSIS; DIABETES MELLITUS, TYPE 2; FOLLOW-UP STUDIES; HUMANS; INTERNATIONALITY; PLATELET AGGREGATION INHIBITORS; PROSPECTIVE STUDIES; TETRAZOLES;

EID: 33749173010     PISSN: 14752840     EISSN: 14752840     Source Type: Journal    
DOI: 10.1186/1475-2840-5-16     Document Type: Article

References (7)

1. Watanabe H, Yamane K, Fujikawa R, Okubo M, Egusa G, Kohno N: Westernization of lifestyle markedly increases carotid intima-media thickness in Japanese people. Atherosclerosis 2003, 166:67-72.
2. Islam MM, Horibe H, Koyabashi F: Current trend in prevalence of diabetes mellitus in Japan, 1964-1992. J Epidemiol 1999, 9:155-162.
3. Kodama M, Yamasaki Y, Sakamoto K, Yoshioka R, Matsuhisa M, Kajimoto Y, Kosugi K, Ueda N, Hori M: Antiplatelet drugs attenuate progression of carotid intima-media thickness in subjects with type 2 diabetes. Thromb Res 2000, 97:239-245.
4. Shinoda-Tagawa T, Yamasaki Y, Yoshida Y, Kajimoto Y, Tsujino T, Hakui N, Matsumoto M, Hori M: A phosphodiesterase inhibitor, cilostazol, prevents the onset of silent brain infarction in Japanese subjects with Type II diabetes. Diabetologia 2002, 45:188-194.
5. Yamasaki Y, Kodama M, Nishizawa H, Sakamoto K, Matsuhisa M, Kajimoto Y, Kosugi K, Shimizu Y, Kawamori R, Hori M: Carotid intima-media thickness in Japanese type 2 diabetic subjects: Predictors of progression and relationship with incident coronary heart disease. Diabetes Care 2000, 23:1310-1315.
6. Mitsuhashi N, Onuma T, Kubo S, Takayanagi N, Honda M, Kawamori R. Coronary artery disease and carotid artery intima-media thickness in Japanese type 2 diabetic patients. Diabetes Care 2002, 25:1308-1312.
7. Sacco M, Pellegrini F, Roncaglioni MC, Avanzini F, Tognoni G, Nicolucci A, PPP Collaborative Group: Primary prevention of cardiovascular events with low-dose aspirin and vitamin E in type 2 diabetic patients: results of the Primary Prevention Project (PPP) trial. Diabetes Care 2003, 26:3264-72.