Apolipoprotein A5 S19W may play a role in dysbetalipoproteinemia in patients with the Apo E2/E2 genotype [6]

Clinical Chemistry

Volumn 52, Issue 10, 2006, Pages 1974-1975

  Martín Campos, Jesus M ^a,b   Rico, Naira ^a   Bonet, Rosa ^a   Mayoral, Carme ^a   Ordóñez Llanos, Jordi ^a,b   Blanco Vaca, Francisco ^a,c  

^a HOSPITAL DE LA SANTA CREU I SANT PAU   (Spain)

^b UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^c HSCSP ^*  (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN A5; APOLIPOPROTEIN E2; APOLIPOPROTEIN E4;

ADULT; AGED; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENOTYPE; HETEROZYGOSITY; HOMOZYGOSITY; HUMAN; HYPERLIPOPROTEINEMIA TYPE 3; LETTER; LIPOPROTEIN METABOLISM; MALE; POLYMERASE CHAIN REACTION;

ADULT; AGED; APOLIPOPROTEIN E2; APOLIPOPROTEINS; APOLIPOPROTEINS A; APOLIPOPROTEINS E; FEMALE; GENOTYPE; HETEROZYGOTE; HUMANS; HYPERLIPOPROTEINEMIA TYPE III; MALE; MIDDLE AGED;

EID: 33749146522     PISSN: 00099147     EISSN: None     Source Type: Journal    
DOI: 10.1373/clinchem.2006.070318     Document Type: Letter

References (6)

1. Schaefer JR, Sattler AM, Hackler B, Kurt B, Hackler R, Maisch B, et al. Hyperlipidemia in patients with apolipoprotein E 2/2 phenotype: apolipoprotein A5 S19W mutation as a cofactor. Clin Chem 2004;50:2214.
2. Civeira F, Pocovi M, Cenarro A, Casao E, Vilella E, Joven J, et al. Apo E variants in patients with type III hyperlipoproteinemia. Atherosclerosis 1996;127:273-82.
3. Pennacchio LA, Olivier M, Hubacek JA, Cohen JC, Cox DR, Fruchart JC, et al. An apolipoprotein influencing triglycerides in humans and mice revealed by comparative sequencing. Science 2001;294:169-73.
4. Ribalta J, Figuera L, Fernandez-Ballart J, Vilella E, Castro CM, Masana L, et al. Newly identified apolipoprotein AV gene predisposes to high plasma triglycerides in familial combined hyperlipidemia. Clin Chem 2002;48: 1597-600.
5. Martin S, Nicaud V, Humphries SE, Talmud PJ. Contribution of APOA5 gene variants to plasma triglyceride determination and to the response to both fat and glucose tolerance challenges. Biochim Biophys Acta 2003;1637: 217-25.
6. de Beer F, Stalenhoef AFH, Hoogerbrugge N, Kastelein JJP, Leuven JAG, van Duijn CM, et al. Expression of type III hyperlipoproteinemia in apolipoprotein E2 (Arg158→Cys) homozygotes is associated with hyperinsulinemia. Arterioscler Thromb Vasc Biol 2002;22:294-9.