False reduction in serum methadone concentrations by BD Vacutainer® serum separator tubes (SST™) [5]

Clinical Chemistry

Volumn 52, Issue 10, 2006, Pages 1972-1974

  Berk, Steven I ^a,c   Litwin, Alain H ^a   Du, Yunling ^a   Cruikshank, Greg ^a   Gourevitch, Marc N ^b   Arnsten, Julia H ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Montefiore Medical Park   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

METHADONE; PEGINTERFERON ALPHA2B;

ANALYTICAL ERROR; CLINICAL ARTICLE; CONTAINER; DRUG BLOOD LEVEL; DRUG DETERMINATION; HEPATITIS C; HUMAN; LETTER; METHADONE TREATMENT; OPIATE ADDICTION;

BLOOD SPECIMEN COLLECTION; FALSE NEGATIVE REACTIONS; HUMANS; METHADONE; NARCOTICS; SERUM;

EID: 33749145135     PISSN: 00099147     EISSN: None     Source Type: Journal    
DOI: 10.1373/clinchem.2006.072132     Document Type: Letter

References (6)

1. Dasgupta A, Dean R, Saldana S, Kinnaman G, McLawhon RW. Absorption of therapeutic drugs by barrier gels in serum separator blood collection tubes: volume- and time-dependent reduction in total and free drug concentrations. Am J Clin Pathol 1994;101:456-61.
2. Dasgupta A, Blackwell W, Bard D. Stability of therapeutic drug measurement in specimens collected in Vacutainer plastic blood-collection tubes. Ther Drug Monit 1996;18:306-9.
3. Karppi J, Akerman KK, Parvlainen M. Suitability of collection tubes with separator gels for collecting and storing blood samples for therapeutic drug monitoring (TDM). Clin Chem Lab Med 2000;38:313-20.
4. BD White Paper VS7049. Therapeutic drug compatibility in BD Vacutainer® SST™ Plus plastic tubes. 2003.
5. Landt M, Smith CH, Hortin GL. Evaluation of evacuated blood-collection tubes: effects of three types of polymeric separators on therapeutic drug-monitoring specimens. Clin Chem 1993; 39:1712-7.
6. McCance-Katz EF, Rainey PM, Friedland G, Jatlow P. The protease inhibitor lopinavir-ritonavir may produce opiate withdrawal in methadone-maintained patients. Clin Infect Dis 2003;37: 476-82.