Influence of tamsulosin on the iris and its implications for cataract surgery

Investigative Ophthalmology and Visual Science

Volumn 47, Issue 9, 2006, Pages 3766-3771

  Pärssinen, Olavi ^a   Leppänen, Esa ^a   Keski Rahkonen, Pekka ^b   Mauriala, Timo ^b   Dugué, Benoit ^c   Lehtonen, Marko ^b  

^a JYVÄSKYLÄ CENTRAL HOSPITAL   (Finland)

^b UNIVERSITY OF EASTERN FINLAND   (Finland)

^c UNIVERSITÉ DE POITIERS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ALLOPURINOL; ALPHA 1 ADRENERGIC RECEPTOR; ALPHA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; AMLODIPINE; ATORVASTATIN; BECLOMETASONE; BISOPROLOL; DIGOXIN; ENALAPRIL; ESOMEPRAZOLE; EXPROS; FERROUS SULFATE; FLUTICASONE; FOLIC ACID; FUROSEMIDE; IBUPROFEN; ISOSORBIDE DINITRATE; METOCLOPRAMIDE; NIFEDIPINE; PANTOPRAZOLE; PHENYLEPHRINE; POTASSIUM CHLORIDE; PROPOFOL; QUINAPRIL; SALBUTAMOL; SALMETEROL; SIMVASTATIN; TAMSULOSIN; THEOPHYLLINE; UNCLASSIFIED DRUG; UNINDEXED DRUG; WARFARIN; ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; ANTINEOPLASTIC AGENT; SULFONAMIDE;

ADULT; AGED; AQUEOUS HUMOR; ARTICLE; CATARACT; CATARACT EXTRACTION; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG EFFECT; HUMAN; IRIS DISEASE; IRIS HYPOTONIA; IRIS PROLAPSE; MALE; MIOSIS; PREOPERATIVE EVALUATION; PRIORITY JOURNAL; PUPIL; CHEMICALLY INDUCED DISORDER; DRUG ANTAGONISM; IRIS; METABOLISM; MIDDLE AGED; PROSTATE HYPERTROPHY; TISSUE INJURY;

ADRENERGIC ALPHA-ANTAGONISTS; AGED; AGED, 80 AND OVER; ANTINEOPLASTIC AGENTS; AQUEOUS HUMOR; CATARACT EXTRACTION; HUMANS; IRIS; IRIS DISEASES; MALE; MIDDLE AGED; MIOSIS; PROLAPSE; PROSTATIC HYPERPLASIA; PUPIL; RECEPTORS, ADRENERGIC, ALPHA-1; SULFONAMIDES;

EID: 33749135468     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: 10.1167/iovs.06-0153     Document Type: Article

References (20)

1. Dunn CJ, Matheson A, Faulds DM. Tamsulosin: a review of its pharmacology and therapeutic efficacy in the management of lower urinary tract symptoms. Drugs Aging. 2002;19:135-1612.
2. Chapple C, Andersson KE. Tamsulosin: an overview. World J Urol. 2002;19:397-404.
3. Konno F, Takayanagi I. Characterization of postsynaptic alpha-1 adrenoreceptors In the rabbit iris dilator smooth muscle. Naunyn- Schmiederberg's Arch Pharmacol. 1986;333:271-276.
4. Nakamura S, Taniguchi T, Suzuki F, Akagi Y, Muramatsu I. Evaluation of alpha-1 adrenoreceptors in the rabbit iris: pharmacological characterization and expression of mRNA. Br J Pharmacol. 1999;127:1367-1374.
5. Suzuki F, Taniguchi T, Nakamura S, et al. Distribution of alpha-1 adrenoreceptor subtypes in RNA and protein in rabbit eyes. Br J Pharmacol. 2002;135:600-608.
6. Chang DF, Campell JR. Intraoperative floppy iris syndrome associated with tamsulosin. J Cataract Refract Surg. 2005;31:664-673.
7. Pärssinen O. The use of tamsulosin and iris hypotony during cataract surgery. Acta Ophthalmol. 2005;83:624-626.
8. 1-Adrenergic antagonists and floppy iris syndrome: tip of the iceberg? Ophthalmology. 2005;112:2059-2060.
9. 1-adrenoreceptors to characterize subtype selectivity of drugs for the treatment of prostatic hypertrophy. Eur J Pharmacol. 1996;288:201-207.
10. Leonardi A, Hieble JP, Guarneri L, et al. Characterization of the uroselective apha-1 antagonist Rec 15/2739 (SB216469): role of the alpha-1L adrenoreceptor in tissue selectivity, part 1. J Pharmacol Exp Ther. 1997;281:1272-1283.
11. Tagushi K, Saitoh M, Sato S, Asano M, Michel MC. Effects of tamsulosin metabolites at alpha-1 adrenoreptor subtypes. J Pharmacol Exp Ther. 1997;280:1-5.
12. Sato S, Ohtake A, Matsushima H, Saitoh C, Usuda S, Miyta K. Pharmacological effect of tamsulosin in relation to dog plasma and tissue concentrations: prostatic and urethral retention of possible contributes to uroselectivity of tamsulosin. J Pharmacol Exp Ther. 2001;296:697-703.
13. Helzner J. Managing floppy iris syndrome: use of Flomax has been tied to this complication. Ophthalmol Manag (serial online). April 2005. Available at: http://www.ophmanagement.com/article.aspx?article=86311. Accessed May 1, 2005.
14. National Agency for Medicines. Consumption of Medicines in Years 2001-2004. Available at: http://raportit.nam.fi/raportit/kulutus/ laakekulutus.htm.
15. Loga S, Curry S, Lader M. Interaction of chlorpromazine and nortriptyline in patients with schizophrenia. Clin Pharmacokinet. 1981;6:454-462.
16. Hart WM. Adler's Physiology of the Eye: Clinical Application. 9th ed. Hart WM, ed. St. Louis: Mosby-Year Book; 1992:237-242.
17. Lawrentschuk N, Bylsma GV. Intraoperative "floppy iris" syndrome and its relationship to tamsulosin: a urologist's guide. BJU Int. 2006;97:2-4.
18. Terry K, De Stefano J, Miller S, Stinnet S, Proia A. Effect of tamsulosin on iris smooth muscle anatomy and adrenergic innervation. Presented at: ASCRS-ASOA 2006 Symposium and Congress; March 17-22, 2006; San Francisco. Poster 37.
19. Gurbaxani A, Packard R. Intracameral phenylephrine to prevent floppy iris syndrome during cataract surgery in patients on tamsulosin. Eye. In press.
20. Reitz A, Haferkamp A, Kyburz T, Knapp PA, Wefer B, Schurch B. The effect of tamsulosin on the resting tone and the contractile behaviour of the female urethra: a functional urodynamic study in healthy women. Eur Urol. 2004;46:235-240.