Treatment of multiple sclerosis with interferon beta in clinical practice: 2-year follow-up data from the South Italy Mobile MRI Project

Neurological Sciences

Volumn 27, Issue SUPPL. 5, 2006, Pages

  Bonavita, S ^a   Dinacci, D ^a   Lavorgna, L ^a   Savettieri, G ^b   Quattrone, A ^c   Livrea, P ^d   Bresciamorra, V ^e   Orefice, G ^e   Paciello, M ^f   Coniglio, G ^f   Di Costanzo, A ^a   Valentino, P ^c   Patti, F ^g   Salemi, G ^b   Simone, I ^d   Tedeschi, Gioacchino ^a  

^a SECOND UNIVERSITY OF NAPLES   (Italy)

^b UNIVERSITY OF PALERMO   (Italy)

^c UNIVERSITY MAGNA GRAECIA OF CATANZARO   (Italy)

^d UNIVERSITY OF BARI   (Italy)

^e UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^f SAN CARLO HOSPITAL   (Italy)

^g UNIVERSITY OF CATANIA   (Italy)

Author keywords

Interferon beta; Multiple sclerosis; Odds ratio; Phase IV

Indexed keywords

BETA INTERFERON; BETA1A INTERFERON; INTERFERON BETA SERINE;

ARTICLE; CLINICAL PRACTICE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; FOLLOW UP; HUMAN; ITALY; MAJOR CLINICAL STUDY; MULTICENTER STUDY; MULTIPLE SCLEROSIS; NUCLEAR MAGNETIC RESONANCE IMAGING; TREATMENT OUTCOME;

ANALYSIS OF VARIANCE; BIOLOGICAL RESPONSE MODIFIERS; CONFIDENCE INTERVALS; FOLLOW-UP STUDIES; HUMANS; INTERFERON-BETA; ITALY; MAGNETIC RESONANCE IMAGING; MULTIPLE SCLEROSIS; ODDS RATIO; SEVERITY OF ILLNESS INDEX;

EID: 33749135029     PISSN: 15901874     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10072-006-0696-6     Document Type: Article

References (10)

1. Benson K, Hartz AJ (2000) A comparison of observational studies and randomized, controlled trials. N Engl J Med 342:1878-1886
2. PRISMS Study Group and the University of British Columbia MS/MRI Analysis Group (2001) PRISMS-4: Long-term efficacy of interferon-beta-1a in relapsing MS. Neurology 56:1628-1636
3. Miller DH (2002) MRI monitoring of MS in clinical trials. Clin Neurol Neurosurg 104:236-243
4. Paolillo A, Bastianello S, Frontoni M et al (1999) Magnetic resonance imaging outcome of new enhancing lesions in relapsing-remitting multiple sclerosis patients treated with interferon beta1a. J Neurol 246:443-448
5. Tedeschi G, Lavorgna L, Russo P et al (2005) Brain atrophy and lesion load in a large population of patients with multiple sclerosis. Neurology 65:280-285
6. Panitch H, Goodin DS, Francis G et al (2002) Randomized, comparative study of interferon beta-1a treatment regimens in MS: The EVIDENCE trial. Neurology 59:1496-1506
7. Durelli L, Verdun E, Barbero P et al (2002) Every-other-day interferon beta-1b versus once-weekly interferon beta-1a for multiple sclerosis: results of a 2-year prospective randomized multicentre study (INCOMIN). Lancet 359:1453-1460
8. Simon JH, Jacobs LD, Campion MK et al (1999) A longitudinal study of brain atrophy in relapsing multiple sclerosis. The Multiple Sclerosis Collaborative Research Group (MSCRG). Neurology 53:139-148
9. Gasperini C, Pozzilli C, Bastianello S et al (1999) Interferonbeta-1a in relapsing-remitting multiple sclerosis: Effect on hypointense lesion volume on T1 weighted images. J Neurol Neurosurg Psychiatry 67:579-584
10. Concato J, Shah N, Horwitz RI (2000) Randomized, controlled trials, observational studies, and the hierarchy of research designs. N Engl J Med 342:1887-1892