Role of C-reactive protein, reticulocyte haemoglobin content and inflammatory markers in iron and erythropoietin administration in dialysis patients

Nephrology

Volumn 11, Issue 5, 2006, Pages 400-404

  El Khatib, Mahmoud ^a,b   Duncan, Heather J ^a   Kant, K Shashi ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b NONE   (United States)

Author keywords

Anaemia; C reactive protein; End stage renal failure; Erythropoietin; Iron; Reticulocyte haemoglobin content

Indexed keywords

ALBUMIN; BIOLOGICAL MARKER; C REACTIVE PROTEIN; FERRITIN; FIBRINOGEN; HEMOGLOBIN; HOMOCYSTEINE; IRON; LIPOPROTEIN A; RECOMBINANT ERYTHROPOIETIN; TRANSFERRIN;

ADULT; AGED; ANEMIA; ARTERIOVENOUS FISTULA; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE MARKER; DOSE RESPONSE; FEMALE; FERRITIN BLOOD LEVEL; HEMODIALYSIS; HEMODIALYSIS PATIENT; HUMAN; INFLAMMATION; IRON DEFICIENCY; KIDNEY FAILURE; MALE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN DETERMINATION; RETICULOCYTE HEMOGLOBIN CONTENT; TRANSFERRIN BLOOD LEVEL;

ACUTE-PHASE REACTION; AGED; ANEMIA; BIOLOGICAL MARKERS; C-REACTIVE PROTEIN; DRUG RESISTANCE; ERYTHROPOIETIN; FEMALE; FERRITINS; HEMOGLOBINS; HUMANS; IRON; KIDNEY FAILURE, CHRONIC; MALE; MIDDLE AGED; RENAL DIALYSIS; RETICULOCYTES; TRANSFERRIN;

EID: 33749126075     PISSN: 13205358     EISSN: 14401797     Source Type: Journal    
DOI: 10.1111/j.1440-1797.2006.00676.x     Document Type: Article

References (20)

1. Qureshi A, Alvestrand A, Divino-Filho J et al. Inflammation, malnutrition, and cardiac disease as predictors of mortality in hemodialysis patients. J. Am. Soc. Nephrol. 2002; 13 (Suppl. 1): s28-s36.
2. Barany P, Divino Filho JC, Bergstrom J. High C-reactive protein is a strong predictor of resistance to erythropoietin in hemodialysis patients. Am. J. Kidney Dis. 1997; 29: 565-8.
3. Baynes RD. Assessment of iron status. Clin. Biochem. 1996; 29: 209-15.
4. Thomas C, Thomas L. Biochemical markers and hematologic indices in the diagnosis of functional iron deficiency. Clin. Chem. 2002; 48: 1066-76.
5. NKF-K/DOQI. NKF-K/DOQI clinical practice guidelines for anemia of chronic kidney disease: Update 2000. Am. J. Kidney Dis. 2001; 31 (Suppl. 1): s182-s288.
6. Fishbane S, Kalantar-Zadeh K, Nissenson AR. Serum ferritin in chronic kidney disease: Reconsidering the upper limit for iron treatment. Semin. Dial. 2004; 17: 336-41.
7. Fishbane S, Galgano C, Langley RC Jr, Canfield W, Maesaka JK. Reticulocyte hemoglobin content in the evaluation of iron status of hemodialysis patients. Kidney Int. 1997; 52: 217-22.
8. Fishbane S, Shapiro W, Dutka P, Valenzuela OF, Faubert J. A randomized trial of iron deficiency testing strategies in hemodialysis patients. Kidney Int. 2001; 60: 2406-11.
9. Worwood M. The laboratory assessment of iron status - an update. Clin. Chim. Acta 1997; 259: 3-23.
10. Lieu PT, Heiskala M, Peterson PA, Yang Y. The roles of iron in health and disease. Mol. Aspects Med. 2001; 22: 1-87.
11. Hackeng CM, Beerenhout CM, Hermans M et al. The relationship between reticulocyte hemoglobin content with C-reactive protein and conventional iron parameters in dialysis patients. J. Nephrol. 2004; 17: 107-11.
12. Mitsuiki K, Harada A, Miyata Y. Reticulocyte hemoglobin content in hemodialysis patients with acute infection. Clin. Exp. Nephrol. 2004; 8: 257-62.
13. Witte DL. Can serum ferritin be effectively interpreted in the presence of the acute-phase response? Clin. Chem. 1991; 37: 484-5.
14. Cavill I. Iron status as measured by serum ferritin: The marker and its limitations. Am. J. Kidney Dis. 1999; 34 (Suppl. 2): s12-s17.
15. Thomas L. Transferrin saturation. In: Thomas L (ed.). Clinical Laboratory Diagnostics. Frankfurt: TH-Books, 1998; 275-7.
16. Skarmoutsou C, Papassotiriou I, Traeger-Synodinos J et al. Erythroid bone marrow activity and red cell hemoglobinization in iron sufficient beta-thalassemia heterozygotes as reflected by soluble transferrin receptor and reticulocyte hemoglobin in content. Correlation with genotypes and Hb A(2) levels. Haematologica 2003; 88: 631-6.
17. Besarab A. Evaluating iron sufficiency: A clearer view. Kidney Int. 2001; 60: 2412-4.
18. Canavese C, Bergamo D, Ciccone G et al. Validation of serum ferritin values by magnetic susceptometry in predicting iron overload in dialysis patients. Kidney Int. 2004; 65: 1091-8.
19. Ali M, Rigolosi R, Fayemi AO, Braun EV, Frascino J. SingerFailure of serum ferritin levels to predict bone-marrow iron content after intravenous iron-dextran therapy. Lancet 1982; 1: 652-5.
20. Goicoechea M, Caramelo C, Rodriguez P et al. Role of type of vascular access in erythropoietin and intravenous iron requirements in haemodialysis. Nephrol. Dial. Transplant. 2001; 16: 2188-93.