Ipsilateral breast tumor reappearance in patients treated with conservative surgery after primary chemotherapy. The role of surgical margins on outcome

Journal of Surgical Oncology

Volumn 94, Issue 5, 2006, Pages 375-379

  Gentilini, Oreste ^a   Intra, Mattia ^a   Gandini, Sara ^a   Peruzzotti, Giulia ^a   Winnikow, Erik ^a   Luini, Alberto ^a   Veronesi, Paolo ^b   Galimberti, Viviana ^a   Goldhirsch, Aron ^a   Veronesi, Umberto ^a  

^a EUROPEAN INSTITUTE OF ONCOLOGY   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

Author keywords

Breast conservation; Local relapse; Primary chemotherapy

Indexed keywords

ANTHRACYCLINE ANTIBIOTIC AGENT; CISPLATIN; CYCLOPHOSPHAMIDE; DOCETAXEL; DOXORUBICIN; EPIRUBICIN; FLUOROURACIL; FOLINATE CALCIUM; NAVELBINE; TAXANE DERIVATIVE;

ADULT; AGED; ARTICLE; BREAST CONSERVATION SURGERY; BREAST SURGERY; BREAST TUMOR; CANCER CHEMOTHERAPY; CANCER MORTALITY; CANCER RECURRENCE; CANCER RELAPSE; CONTINUOUS INFUSION; FEMALE; FOLLOW UP; HUMAN; HUMAN TISSUE; INCIDENCE; INFUSION SYSTEM; MAJOR CLINICAL STUDY; MASTECTOMY; METASTASIS; OUTCOME ASSESSMENT; PATIENT SELECTION; PREOPERATIVE CARE; PRIORITY JOURNAL; RECURRENCE RISK; SURVIVAL RATE; TUMOR VOLUME;

ADULT; AGED; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BREAST NEOPLASMS; CISPLATIN; CYCLOPHOSPHAMIDE; DOXORUBICIN; DRUG ADMINISTRATION SCHEDULE; EPIRUBICIN; FEMALE; FLUOROURACIL; FOLLOW-UP STUDIES; HUMANS; MASTECTOMY, MODIFIED RADICAL; MASTECTOMY, SEGMENTAL; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; PROGNOSIS; REOPERATION; SURVIVAL RATE; TREATMENT OUTCOME;

EID: 33749077084     PISSN: 00224790     EISSN: 10969098     Source Type: Journal    
DOI: 10.1002/jso.20583     Document Type: Article

References (16)

1. Fisher B, Bryant J, Wolmark N, et al.: Effect of preoperative chemotherapy on the outcome of women with operable breast cancer. J Clin Oncol 1998;16:2672-2685.
2. Van der Hage JA, van de Velde CJ, Julien JP, et al.: Preoperative chemotherapy in primary operable breast cancer: Results from the European Organization for Research and Treatment of Cancer trial 10902. J Clin Oncol 2001;19:4224-4237.
3. Veronesi U, Bonadonna G, Zurrida S, et al.: Conservation surgery after primary chemotherapy in large carcinomas of the breast. Ann Surg 1995;222:612-618.
4. Smith IE, Lipton L: Preoperative/neoadjuvant medical therapy for early breast cancer. Lancet Oncol 2001;2:561-570.
5. Touboul E, Lefranc JP, Blondon J, et al.: Primary chemotherapy and preoperative irradiation for patients with stage II larger than 3 cm or locally advanced noninflammatory breast cancer. Radiother Oncol 1997;42:219-229.
6. Calais G, Berger C, Descamps P, et al.: Conservative treatment feasibility with induction chemotherapy, surgery, and radiotherapy for patients with breast carcinoma larger than 3 cm. Cancer 1994;74:1283-1288.
7. Rouzier R, Extra JM, Carton M, et al.: Primary chemotherapy for operable breast cancer: Incidence and prognostic significance of ipsilateral breast tumor recurrence after breast conserving surgery. J Clin Oncol 2001;19:3828-3835.
8. Perloff M, Lesnick GJ, Korzun A, et al.: Combination chemotherapy with mastectomy or radiotherapy for stage III breast cancer: A cancer and leukemia group B study. J Clin Oncol 1988;6:261-269.
9. Broet P, Scholl SM, de la Rochefordiere A, et al.: Short and long-term effects on survival in breast cancer patients treated by primary chemotherapy: An updated analysis of a randomized trial. Breast Cancer Res Treat 1999;58:151-156.
10. Veronesi U, Ma rubini E, Marianl L, et al.: Radiotheraphy after breast-conserving surgery in small breast carcinoma: Long-term results of a randomised trial. Ann Oncol 2001;12: 997-1003.
11. Colleoni M, Viale G, Zahrieh D, et al.: Chemotherapy is more effective in patients with breast cancer not expressing steroid hormone receptors: A study of preoperative treatment. Clin Cancer Res 2004;10:6622-6628.
12. Marubini E, Valsecchi MG: Analysing survival data from clinical trials and observational studies. Chichester, England: Wiley; 1995; 331p.
13. Gray RJ: A class of k-sample tests for comparing the cumulative incidence of a competing risk. Ann Stat 1988;16:1141-1154.
14. Schwartz G, Hortobagyi G, and the Consensus Conference Committee. Proceedings of the Consensus Conference on Neoadjuvant Chemotherapy in Carcinoma of the Breast, April 26-28, 2003, Philadelphia, Pennsylvania. Cancer 2004;100: 2512-2532.
15. Fisher B, Brown A, Mamounas E, et al.: Effect of preoperative chemotherapy on local-regional disease in women with operable breast cancer: Findings from National Surgical Adjuvant Breast and Bowel Project B-18. J Clin Oncol 1997;15:2483-2493.
16. Chen AM, Meric-Bernstam F, Hunt KK, et al.: Breast conservation after neoadjuvant chemotherapy: The M.D. Anderson Cancer Center Experience. J Clin Oncol 2004, 22:2303-2312.