Erythromycin alters the pharmacokinetics of bromocriptine by inhibition of organic anion transporting polypeptide C-mediated uptake

Clinical Pharmacology and Therapeutics

Volumn 80, Issue 4, 2006, Pages 421-422

  Lu, Wen Jen ^a   Huang, Kelly ^b   Lai, Ming Liang ^b   Huang, Jin ding ^c  

^a Institute of Basic Medical Sciences   (Taiwan)

^b Department of Neurology ^*

^c NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

BROMOCRIPTINE; CYTOCHROME P450 3A4; ERYTHROMYCIN; ORGANIC ANION TRANSPORTER 2; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

CELL STRAIN HEK293; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG LIVER LEVEL; DRUG METABOLISM; DRUG UPTAKE; EMBRYO; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; LETTER; LIVER MICROSOME; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE;

ANTI-BACTERIAL AGENTS; ANTIPARKINSON AGENTS; BROMOCRIPTINE; CYTOCHROME P-450 ENZYME SYSTEM; DOPAMINE AGONISTS; ERYTHROMYCIN; HUMANS; ORGANIC ANION TRANSPORT POLYPEPTIDE C;

EID: 33749063630     PISSN: 00099236     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clpt.2006.06.003     Document Type: Letter

References (5)

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4. TP-search. Transporter database. Available from: URL:http://www.tp-search.jp. Accessed March 1, 2006.
5. Lu W.J., Tamai I., Nezu J.I., Lai M.L., and Huang J.D. Organic anion transporting polypeptide-C mediates arsenic uptake in HEK-293 cells. J Biomed Sci 13 (2006) 525-533