Treatment of Benign Diseases with Megavoltage X-ray Beams: Is there a Risk for Gonadal Damage?

Clinical Oncology

Volumn 18, Issue 9, 2006, Pages 658-662

  Kokona, G ^a   Mazonakis, M ^a   Varveris, H ^a   Liraraki, E ^a   Damilakis, J ^a  

^a UNIVERSITY HOSPITAL OF IRAKLION   (Greece)

Author keywords

Gonadal damage; gonadal dose; hereditary effects; infertility; non malignant diseases; radiotherapy of benign diseases

Indexed keywords

ARTICLE; BENIGN TUMOR; BONE CYST; CONTROLLED STUDY; DOSIMETRY; ENDOCRINE OPHTHALMOPATHY; FREQUENCY ANALYSIS; GENETIC DISORDER; GONAD DYSFUNCTION; GYNECOMASTIA; HUMAN; LIVER HEMANGIOMA; MEGAVOLTAGE RADIOTHERAPY; OVARY; PHOTON THERAPY; PRIORITY JOURNAL; RADIATION BEAM; RADIATION DOSE; RISK ASSESSMENT; SIMULATION; TESTIS; THERMOLUMINESCENCE DOSIMETRY;

BONE CYSTS; DOSE-RESPONSE RELATIONSHIP, RADIATION; EXOPHTHALMOS; FEMALE; GONADAL DISORDERS; GYNECOMASTIA; HEMANGIOMA; HUMANS; MALE; OSSIFICATION, HETEROTOPIC; OVARY; RADIATION INJURIES; RADIOTHERAPY DOSAGE; RADIOTHERAPY, HIGH-ENERGY; RISK ASSESSMENT; TESTIS; X-RAY THERAPY;

EID: 33749050569     PISSN: 09366555     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clon.2006.07.013     Document Type: Article

References (23)

1. Seegenschmiedt M.H., Katalanic A., Makoski H., Haase W., Gademann G., and Hassenstein E. Radiation therapy for benign diseases patterns of care study in Germany. Int J Radiat Oncol Biol Phys 47 (2000) 195-202
2. Perez C., and Brady L. Principle and practice of radiation oncology. In: Sebber W., Luther W.B., and Hope R.T. (Eds). Radiation treatment of benign diseases. 4th edn (2004), Lippincott Williams and Wilkins, Philadelphia 2332-2345
3. Rowley M.J., Leach D.R., Warner G.A., and Heller C.G. Effect of graded doses of ionizing irradiation on the human testis. Radiat Res 59 (1974) 665-678
4. Shapiro E., Kinsella T.J., Makuch R.W., et al. Effects of fractionated irradiation on endocrine aspects of testicular function. J Clin Oncol 3 (1985) 1223-1239
5. Howell S., and Shalet S. Gonadal damage from chemotherapy and radiotherapy. Endocrinol Metab Clin North Am 27 (1998) 927-943
6. Darby S., Reeve G., Key T., Doll R., and Stoval M. Mortality in a cohort of women given X-ray therapy for metropathia haemorrhagica. Int J Cancer 59 (1981) 793-801
7. Griem M.L., Kleinerman R.A., Boice Jr. J.D., Stovall M., Shefner D., and Lubin J.H. Cancer following radiotherapy for peptic ulcer. J Natl Cancer Inst 86 (1994) 842-849
8. Weiss H.A., Darby S.C., and Doll R. Cancer mortality following X-ray treatment for ankylosing spondylitis. Int J Cancer 59 (1994) 327-338
9. Jansen J.T.H.M., Boerse J.J., Zoetelief J., et al. Estimation of the carcinogenic risk of radiotherapy of benign disease from shoulder to heel. Radiother Oncol 76 (2005) 270-277
10. Niroomand-Rad A., and Cuberlin R. Measured dose to ovaries and testes from Hodgkin's fields and determination of genetically significant dose. Int J Radiat Oncol Biol Phys 25 (1993) 745-751
11. Budgell G.J., Cowan R.A., and Housnell A.R. Prediction of scattered dose to the testes in abdominopelvic radiotherapy. Clin Oncol 13 (2001) 120-125
12. Amies C.J., App M., Mameghan H., et al. Testicular doses in definitive radiation therapy for localized prostate cancer. Int J Radiat Oncol Biol Phys 32 (1995) 839-846
13. Mazonakis M., Damilakis J., Theocharopoulos N., Varveris H., and Gourtzoyiannis N. Brain radiotherapy during pregnancy: an analysis of conceptus dose using anthropomorphic phantoms. Br J Radiol 72 (1999) 274-278
14. Mazonakis M., Damilakis J., Varveris H., and Gourtzoyiannis N. Therapeutic external irradiation in women of reproductive age: risk estimation of hereditary effects. Br J Radiol 77 (2004) 847-850
15. Gray J.E., Ragozzino M.W., Van Lysel M.S., and Burke T.M. Normalized organ doses for various diagnostic radiology procedures. AJR Am J Roentgenol 137 (1981) 463-470
16. International Commission on Radiological Protection. Recommendations of the International Commission on Radiological Protection. ICRP Publication 60 (1991), Pergamon Press, Oxford
17. Sherazi S., and Kase K.R. Measurements of dose from secondary radiation outside the treatment field: effects of wedges and blocks. Int J Radiat Oncol Biol Phys 11 12 (1985) 2171-2176
18. Vander Giesses P.H. Peridose, software program to calculate the dose outside the primary beam in radiation therapy. Radioth Oncol 58 (2001) 209-213
19. Hansen P.V., Trykker H., Svennekjaer I.L., and Hvolby J. Long-term recovery of spermatogenesis after radiotherapy in patients with testicular cancer. Radiother Oncol 18 (1990) 117-125
20. Centola G.M., Keller J.W., Henzler M., and Rubin P. Effect of low-dose testicular irradiation on sperm count and fertility in patients with testicular seminoma. J Androl 15 (1994) 608-613
21. Ash P. The influence of radiation on fertility in man. Br J Radiol 53 (1980) 271-278
22. Hall E.J. Radiobiology for the radiologist. 5th edn (2000), Lippincott Williams and Wilkins, Philadelphia
23. Statkiewicz-Sherer M.A., Visconti P.J., and Ritenour E.R. Radiation protection in medical radiography. 3rd edn (1998), Mosby, St Louis