메뉴 건너뛰기




Volumn 18, Issue 4, 2006, Pages 421-424

Tamoxifen inhibits cytochrome P450 2C9 activity in breast cancer patients

Author keywords

CYP2C9; Drug drug interaction; Inhibition; Tamoxifen

Indexed keywords

2 BUTYL 4 CHLORO 1 [[2' (1H TETRAZOL 5 YL) 4 BIPHENYLYL]METHYL] 5 IMIDAZOLECARBOXYLIC ACID; CYTOCHROME P450 2C9; LOSARTAN; TAMOXIFEN;

EID: 33749038611     PISSN: 1120009X     EISSN: None     Source Type: Journal    
DOI: 10.1179/joc.2006.18.4.421     Document Type: Article
Times cited : (23)

References (21)
  • 1
    • 0032569831 scopus 로고    scopus 로고
    • Tamoxifen in the treatment of breast cancer
    • Osborne CK. Tamoxifen in the treatment of breast cancer. N Engl J Med 1998; 339 (22): 1609-1618.
    • (1998) N Engl J Med , vol.339 , Issue.22 , pp. 1609-1618
    • Osborne, C.K.1
  • 2
    • 19944434201 scopus 로고    scopus 로고
    • CYP2D6 genotype, antidepressant use, and tamoxifen metabolism during adjuvant breast cancer treatment
    • Jin Y, Desta Z, Stearns V et al. CYP2D6 genotype, antidepressant use, and tamoxifen metabolism during adjuvant breast cancer treatment. J Natl Cancer Inst 2005; 97 (1): 30-39.
    • (2005) J Natl Cancer Inst , vol.97 , Issue.1 , pp. 30-39
    • Jin, Y.1    Desta, Z.2    Stearns, V.3
  • 3
    • 0036850662 scopus 로고    scopus 로고
    • Identification of human CYP forms involved in the activation of tamoxifen and irreversible binding to DNA
    • Boocock DJ, Brown K, Gibbs AH, Sanchez E, Turteltaub KW, White IN. Identification of human CYP forms involved in the activation of tamoxifen and irreversible binding to DNA. Carcinogenesis 2002; 23 (11): 1897-1901.
    • (2002) Carcinogenesis , vol.23 , Issue.11 , pp. 1897-1901
    • Boocock, D.J.1    Brown, K.2    Gibbs, A.H.3    Sanchez, E.4    Turteltaub, K.W.5    White, I.N.6
  • 4
    • 84970843754 scopus 로고
    • Life threatening interaction between tamoxifen and warfarin
    • Lodwick R, McConkey B, Brown AM. Life threatening interaction between tamoxifen and warfarin. Br Med J (Clin Res Ed) 1987; 295 (6606): 1141.
    • (1987) Br Med J (Clin Res Ed) , vol.295 , Issue.6606 , pp. 1141
    • Lodwick, R.1    McConkey, B.2    Brown, A.M.3
  • 5
    • 0024507312 scopus 로고
    • Life threatening interaction between tamoxifen and warfarin
    • Tenni P, Lalich DL, Byrne MJ. Life threatening interaction between tamoxifen and warfarin. BMJ 1989; 298 (6666): 93.
    • (1989) BMJ , vol.298 , Issue.6666 , pp. 93
    • Tenni, P.1    Lalich, D.L.2    Byrne, M.J.3
  • 6
    • 0024507146 scopus 로고
    • Tamoxifen-warfarin interaction: The Aberdeen hospitals drug file
    • Ritchie LD, Grant SM. Tamoxifen-warfarin interaction: the Aberdeen hospitals drug file. BMJ 1989; 298 (6682): 1253.
    • (1989) BMJ , vol.298 , Issue.6682 , pp. 1253
    • Ritchie, L.D.1    Grant, S.M.2
  • 7
    • 0028968645 scopus 로고
    • High-dose tamoxifen in treatment of brain tumors: Interaction with antiepileptic drugs
    • Rabinowicz AL, Hinton DR, Dyck P, Couldwell WT. High-dose tamoxifen in treatment of brain tumors: interaction with antiepileptic drugs. Epilepsia 1995; 36 (5): 513-515.
    • (1995) Epilepsia , vol.36 , Issue.5 , pp. 513-515
    • Rabinowicz, A.L.1    Hinton, D.R.2    Dyck, P.3    Couldwell, W.T.4
  • 8
    • 11844304376 scopus 로고    scopus 로고
    • Clinical consequences of cytochrome P450 2C9 polymorphisms
    • Kirchheiner J, Brockmoller J. Clinical consequences of cytochrome P450 2C9 polymorphisms. Clin Pharmacol Ther 2005; 77 (1): 1-16.
    • (2005) Clin Pharmacol Ther , vol.77 , Issue.1 , pp. 1-16
    • Kirchheiner, J.1    Brockmoller, J.2
  • 9
    • 4043095409 scopus 로고    scopus 로고
    • CYP2C9 genetic variants and losartan oxidation in a Turkish population
    • Babaoglu MO, Yasar U, Sandberg M et al. CYP2C9 genetic variants and losartan oxidation in a Turkish population. Eur J Clin Pharmacol 2004; 60 (5): 337-342.
    • (2004) Eur J Clin Pharmacol , vol.60 , Issue.5 , pp. 337-342
    • Babaoglu, M.O.1    Yasar, U.2    Sandberg, M.3
  • 10
    • 0036161753 scopus 로고    scopus 로고
    • Pharmacokinetics of losartan and its metabolite E-3174 in relation to the CYP2C9 genotype
    • Yasar U, Forslund-Bergengren C, Tybring G et al. Pharmacokinetics of losartan and its metabolite E-3174 in relation to the CYP2C9 genotype. Clin Pharmacol Ther 2002; 71 (1): 89-98.
    • (2002) Clin Pharmacol Ther , vol.71 , Issue.1 , pp. 89-98
    • Yasar, U.1    Forslund-Bergengren, C.2    Tybring, G.3
  • 12
    • 0035032568 scopus 로고    scopus 로고
    • Interindividual variability in inhibition and induction of cytochrome P450 enzymes
    • Lin JH, Lu AY. Interindividual variability in inhibition and induction of cytochrome P450 enzymes. Annu Rev Pharmacol Toxicol 2001; 41: 535-567.
    • (2001) Annu Rev Pharmacol Toxicol , vol.41 , pp. 535-567
    • Lin, J.H.1    Lu, A.Y.2
  • 13
    • 0344303632 scopus 로고    scopus 로고
    • Effect of the single CYP2C9*3 allele on pharmacokinetics and pharmacodynamics of losartan in healthy Japanese subjects
    • Sekino K, Kubota T, Okada Y et al. Effect of the single CYP2C9*3 allele on pharmacokinetics and pharmacodynamics of losartan in healthy Japanese subjects. Eur J Clin Pharmacol 2003; 59 (8-9): 589-592.
    • (2003) Eur J Clin Pharmacol , vol.59 , Issue.8-9 , pp. 589-592
    • Sekino, K.1    Kubota, T.2    Okada, Y.3
  • 14
    • 0034007388 scopus 로고    scopus 로고
    • Phenotyping of drug-metabolizing enzymes in adults: A review of in-vivo cytochrome P450 phenotyping probes
    • Streetman DS, Bertino JS, Jr., Nafziger AN. Phenotyping of drug-metabolizing enzymes in adults: a review of in-vivo cytochrome P450 phenotyping probes. Pharmacogenetics 2000; 10 (3): 187-216.
    • (2000) Pharmacogenetics , vol.10 , Issue.3 , pp. 187-216
    • Streetman, D.S.1    Bertino Jr., J.S.2    Nafziger, A.N.3
  • 15
    • 3543006619 scopus 로고    scopus 로고
    • Functional impact of CYP2C9*5, CYP2C9*6, CYP2C9*8, and CYP2C9*11 in vivo among black Africans
    • Allabi AC, Gala JL, Horsmans Y et al. Functional impact of CYP2C9*5, CYP2C9*6, CYP2C9*8, and CYP2C9*11 in vivo among black Africans. Clin Pharmacol Ther 2004; 76 (2): 113-118.
    • (2004) Clin Pharmacol Ther , vol.76 , Issue.2 , pp. 113-118
    • Allabi, A.C.1    Gala, J.L.2    Horsmans, Y.3
  • 17
    • 0028846142 scopus 로고
    • In vivo inhibition profile of cytochrome P450TB (CYP2C9) by (+/-)-fluvastatin
    • Transon C, Leemann T, Vogt N, Dayer P. In vivo inhibition profile of cytochrome P450TB (CYP2C9) by (+/-)-fluvastatin. Clin Pharmacol Ther 1995; 58 (4): 412-417.
    • (1995) Clin Pharmacol Ther , vol.58 , Issue.4 , pp. 412-417
    • Transon, C.1    Leemann, T.2    Vogt, N.3    Dayer, P.4
  • 18
    • 0036656444 scopus 로고    scopus 로고
    • Effects of terfenadine and diphenhydramine on the CYP2D6 activity in healthy volunteers
    • Kortunay S, Bozkurt A, Basci NE, Kayaalp SO. Effects of terfenadine and diphenhydramine on the CYP2D6 activity in healthy volunteers. Eur J Drug Metab Pharmacokinet 2002; 27 (3): 171-174.
    • (2002) Eur J Drug Metab Pharmacokinet , vol.27 , Issue.3 , pp. 171-174
    • Kortunay, S.1    Bozkurt, A.2    Basci, N.E.3    Kayaalp, S.O.4
  • 19
    • 0035652116 scopus 로고    scopus 로고
    • Dose-dependent inhibition of the CYP2D6 catalyzed oxidation of sparteine by mepyramine in healthy volunteers
    • Kortunay S, Bozkurt A, Basci NE, Brosen K, Kayaalp SO. Dose-dependent inhibition of the CYP2D6 catalyzed oxidation of sparteine by mepyramine in healthy volunteers. Pharmacol Toxicol 2001; 89 (6): 331-334.
    • (2001) Pharmacol Toxicol , vol.89 , Issue.6 , pp. 331-334
    • Kortunay, S.1    Bozkurt, A.2    Basci, N.E.3    Brosen, K.4    Kayaalp, S.O.5
  • 20
    • 0344736918 scopus 로고    scopus 로고
    • Oxidative metabolism of tamoxifen to Z-4-hydroxy-tamoxifen by cytochrome P450 isoforms: An appraisal of in vitro studies
    • Coller JK. Oxidative metabolism of tamoxifen to Z-4-hydroxy-tamoxifen by cytochrome P450 isoforms: an appraisal of in vitro studies. Clin Exp Pharmacol Physiol 2003; 30 (11): 845-848.
    • (2003) Clin Exp Pharmacol Physiol , vol.30 , Issue.11 , pp. 845-848
    • Coller, J.K.1
  • 21
    • 19944393579 scopus 로고    scopus 로고
    • Enzyme kinetics for clinically relevant CYP inhibition
    • Zhang ZY, Wong YN. Enzyme kinetics for clinically relevant CYP inhibition. Curr Drug Metab 2005; 6 (3): 241-257.
    • (2005) Curr Drug Metab , vol.6 , Issue.3 , pp. 241-257
    • Zhang, Z.Y.1    Wong, Y.N.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.