Separation of binding affinity and intrinsic activity of the potent μ-opioid 14-methoxymetopon

Journal of Pharmacology and Experimental Therapeutics

Volumn 319, Issue 1, 2006, Pages 247-253

  Mahurter, Loriann ^a   Garceau, Carrie ^a   Marino, Jacqueline ^a   Schmidhammer, Helmut ^b   Tóth, Géza ^c   Pasternak, Gavril W ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b UNIVERSITY OF INNSBRUCK   (Austria)

^c INSTITUTE OF BIOCHEMISTRY   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

14 METHOXYMETOPON; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; GUANOSINE TRIPHOSPHATE; OPIATE AGONIST; OPIATE PEPTIDE; OPIATE RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING ASSAY; BINDING SITE; BRAIN MEMBRANE; CELL LINE; DRUG ACTIVITY; DRUG POTENCY; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; RECEPTOR AFFINITY; STRIATE CORTEX;

ANIMALS; CATTLE; CORPUS STRIATUM; ENKEPHALIN, ALA(2)-MEPHE(4)-GLY(5)-; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); MORPHINE DERIVATIVES; RECEPTORS, OPIOID, MU;

EID: 33749037461     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.106.105395     Document Type: Article

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