Increased TGF-α and EGF receptor mRNA expression in response to neonatal unilateral partial ureter obstruction in rats

Nephron - Experimental Nephrology

Volumn 104, Issue 2, 2006, Pages

  Bor, Mustafa Vakur ^a,b   Shi, Ymin ^a   Sorensen, Boe S ^a   Jan, Guo Wen ^a   Frokiaer, Jorgen ^a   Djurhuus, Jens Christian ^a   Nexo, Ebba ^a  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

^b AALBORG UNIVERSITY HOSPITAL   (Denmark)

Author keywords

Cell survival factor; Epidermal growth factor receptor; Partial unilateral ureteral obstruction; Transforming growth factor alpha

Indexed keywords

AMPHIREGULIN; BETACELLULIN; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIREGULIN; HEPARIN BINDING EPIDERMAL GROWTH FACTOR; MESSENGER RNA; RIBOSOME RNA; RNA 18S; TRANSFORMING GROWTH FACTOR ALPHA;

AMPLICON; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BODY GROWTH; CELL SURVIVAL; CONTROLLED STUDY; GEL ELECTROPHORESIS; HOUSEKEEPING GENE; KIDNEY DEVELOPMENT; MALE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; RNA ISOLATION; STATISTICAL ANALYSIS; URETER OBSTRUCTION;

ANIMALS; RATS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RNA, MESSENGER; TRANSFORMING GROWTH FACTOR ALPHA; URETERAL OBSTRUCTION;

EID: 33749035271     PISSN: 16602129     EISSN: None     Source Type: Journal    
DOI: 10.1159/000094000     Document Type: Article

References (46)

1. Chevalier RL: Pathophysiology of obstructive nephropathy in the newborn. Semin Nephrol 1998;18:585-593.
2. Nguyen HT, Kogan BA: Upper urinary tract obstruction: experimental and clinical aspects. Br J Urol 1998;81(suppl 2):13-21.
3. Wen JG, Frokiaer J, Jorgensen TM, Djurhuus JC: Obstructive nephropathy: an update of the experimental research. Urol Res 1999;27:29-39.
4. Chevalier RL, Thornhill BA, Wolstenholme JT, Kim A: Unilateral ureteral obstruction in early development alters renal growth: dependence on the duration of obstruction. J Urol 1999;161:309-313.
5. Dicker SE, Shirley DG: Compensatory hypertrophy of the contralateral kidney after unilateral ureteral ligation. J Physiol 1972;220:199-210.
6. Wen JG, Ringgaard S, Frokiaer J, Jorgensen TM, Stodkilde-Jorgensen H, Djurhuus JC: Contralateral compensatory kidney growth in rats with partial unilateral ureteral obstruction monitored by magnetic resonance imaging. J Urol 1999;162:1084-1089.
7. Liapis H, Nag M, Steinhardt G: Effects of experimental ureteral obstruction on platelet-derived growth factor-A and type I procollagen expression in fetal metanephric kidneys. Pediatr Nephrol 1994;8:548-554.
8. Diamond JR, Kees-Folts D, Ding G, Frye JE, Restrepo NC: Macrophages, monocyte chemoattractant peptide-1, and TGF-beta 1 in experimental hydronephrosis. Am J Physiol 1994;266:F926-F933.
9. Steinhardt GF, Liapis H, Phillips B, Vogler G, Nag M, Yoon KW: Insulin-like growth factor improves renal architecture of fetal kidneys with complete ureteral obstruction. J Urol 1995;154:690-693.
10. Walton G, Buttyan R, Garcia-Montes E, Olsson CA, Hensle TW, Sawczuk IS: Renal growth factor expression during the early phase of experimental hydronephrosis. J Urol 1992;148:510-514.
11. Miller SB, Rogers SA, Estes CE, Hammerman MR: Increased distal nephron EGF content and altered distribution of peptide in compensatory renal hypertrophy. Am J Physiol 1992;262:F1032-F1038.
12. Riese DJ, Stern DF: Specificity within the EGF family/ErbB receptor family signaling network. Bioassays 1998;20:41-48.
13. Brown PI, Lam R, Lakshmanan J, Fisher DA: Transforming growth factor alpha in developing rats. Am J Physiol 1990;259:E256-E260.
14. Goodyer PR, Fata J, Mulligan L, Fischer D, Fagan R, Guyda HJ, Goodyer CG: Expression of transforming growth factor-alpha and epidermal growth factor receptor in human fetal kidneys. Mol Cell Endocrinol 1991;77:199-206.
15. Goodyer PR, Fata J, Goodyer CG, Guyda H: Transforming growth factor-alpha and the ontogeny of epidermal growth factor receptors in rat kidney. Growth Regul 1991;1:105-109.
16. Goodyer PR, Mulligan L, Goodyer CG: Expression of growth-related genes in human fetal kidney. Am J Kidney Dis 1991;17:608-610.
17. Harris RC: Potential physiologic roles for epidermal growth factor in the kidney. Am J Kidney Dis 1991;17:627-630.
18. Taub M, Wang Y, Szczesny TM, Kleinman HK: Epidermal growth factor or transforming growth factor alpha is required for kidney tubulogenesis in matrigel cultures in serum-free medium. Proc Natl Acad Sci USA 1990;87:4002-4006.
19. Homma T, Sakai M, Cheng HF, Yasuda T, Coffey RJ Jr, Harris RC: Induction of heparin-binding epidermal growth factor-like growth factor mRNA in rat kidney after acute injury. J Clin Invest 1995;96:1018-1025.
20. Nakagawa T, Hayase Y, Sasahara M, Haneda M, Kikkawa R, Higashiyama S, Taniguchi N, Hazama F: Distribution of heparin-binding EGF-like growth factor protein and mRNA in the normal rat kidneys. Kidney Int 1997;51:1774-1779.
21. Sakai M, Zhang M, Homma T, Garrick B, Abraham JA, McKanna JA, Harris RC: Production of heparin binding epidermal growth factor-like growth factor in the early phase of regeneration after acute renal injury. Isolation and localization of bioactive molecules. J Clin Invest 1997;99:2128-2138.
22. Nguyen HT, Thomson AA, Kogan BA, Baskin LS, Cunha GR: Growth factor expression in the obstructed developing and mature rat kidney. Lab Invest 1999;79:171-184.
23. Wen JG, Chen Y, Frokiaer J, Jorgensen TM, Djurhuus JC: Experimental partial unilateral ureter obstruction. I. Pressure flow relationship in a rat model with mild and severe acute ureter obstruction. J Urol 1998;160:1567-1571.
24. Wen JG, Ringgaard S, Jorgensen TM, Stodkilde-Jorgensen H, Djurhuus JC, Frokiaer J: Long-term effects of partial unilateral ureteral obstruction on renal hemodynamics and morphology in newborn rats: a magnetic resonance imaging study. Urol Res 2002;30:205-212.
25. Sorensen BS, Torring N, Bor MV, Nexo E: The DNA damaging agent VP16 induces the expression of a subset of ligands from the EGF system in bladder cancer cells, whereas none of the four EGF receptors are induced. Mol Cell Biochem 2004;260:129-135.
26. Nguyen HT, Bride SH, Badawy AB, Adam RM, Lin J, Orsola A, Guthrie PD, Freeman MR, Peters CA: Heparin-binding EGF-like growth factor is up-regulated in the obstructed kidney in a cell- and region-specific manner and acts to inhibit apoptosis. Am J Pathol 2000;156:889-898.
27. Wen JG: Partial unilateral ureteral obstruction in rats. Neurourol Urodyn 2002;21:231-250.
28. Kennedy WA 2nd, Stenberg A, Lackgren G, Hensle TW, Sawczuk IS: Renal tubular apoptosis after partial ureteral obstruction. J Urol 1994;152:658-664.
29. Barnard JA, Graves-Deal R, Pittelkow MR, DuBois R, Cook P, Ramsey GW, Bishop PR, Damstrup L, Coffey RJ: Auto- and cross-induction within the mammalian epidermal growth factor-related peptide family. J Biol Chem 1994;269:22817-22822.
30. Sorensen BS, Torring N, Bor MV, Nexo E: Quantitation of the mRNA expression of the epidermal growth factor system: selective induction of heparin-binding epidermal growth factor-like growth factor and amphiregulin expression by growth factor stimulation of prostate stromal cells. J Lab Clin Med 2000;136:209-217.
31. Hayslett JP: Functional adaptation to reduction in renal mass. Physiol Rev 1979;59:137-164.
32. Diaz-Ruiz C, Perez-Tomas R, Cullere X, Domingo J: Immunohistochemical localization of transforming growth factor-alpha and epidermal growth factor-receptor in the mesonephros and metanephros of the chicken. Cell Tissue Res 1993;271:3-8.
33. Avner ED, Sweeney WE Jr: Polypeptide growth factors in metanephric growth and segmental nephron differentiation. Pediatr Nephrol 1990;4:372-377.
34. Avner ED: Polypeptide growth factors and the kidney: a developmental perspective. Pediatr Nephrol 1990;4:345-353.
35. Briere N, Bertrand L, Ferrari J: Mouse fetal kidneys in serum-free organ culture: effects of epidermal growth factor and hydrocortisone. Comp Biochem Physiol [A] 1991;98:421-430.
36. Rogers SA, Ryan G, Hammerman MR: Metanephric transforming growth factor-alpha is required for renal organogenesis in vitro. Am J Physiol 1992;262:F533-F539.
37. Lee DC, Chan KW, Chan SY: Expression of transforming growth factor alpha and epidermal growth factor receptor in adult polycystic kidney disease. J Urol 1998;159:291-296.
38. Lowden DA, Lindemann GW, Merlino G, Barash BD, Calvet JP, Gattone VH: Renal cysts in transgenic mice expressing transforming growth factor-alpha. J Lab Clin Med 1994;124:386-394.
39. Wolf G. 'As time goes by': angiotensin II-mediated transactivation of the EGF receptor comes of age. Nephrol Dial Transplant 2005;20:2050-2053.
40. Lautrette A, Li S, Alili R, Sunnarborg SW, Burtin M, Lee DC, Friedlander G, Terzi F: Angiotensin II and EGF receptor cross-talk in chronic kidney diseases: a new therapeutic approach. Nat Med 2005;11:867-874.
41. Wong RW, Kwan RW, Mak PH, Mak KK, Sham MH, Chan SY: Overexpression of epidermal growth factor induced hypospermatogenesis in transgenic mice. J Biol Chem 2000;275:18297-18301.
42. Nouwen EJ, De Broe ME: EGF and TGF-alpha in the human kidney: identification of octopal cells in the collecting duct. Kidney Int 1994;45:1510-1521.
43. Horikawa M, Higashiyama S, Nomura S, Kitamura Y, Ishikawa M, Taniguchi N: Upregulation of endogenous heparin-binding EGF-like growth factor and its role as a survival factor in skeletal myotubes. FEBS Lett 1999;459:100-104.
44. Takemura T, Kondo S, Homma T, Sakai M, Harris RC: The membrane-bound form of heparin-binding epidermal growth factor-like growth factor promotes survival of cultured renal epithelial cells. J Biol Chem 1997;272:31036-31042.
45. Coles HS, Burne JF, Raff MC: Large-scale normal cell death in the developing rat kidney and its reduction by epidermal growth factor. Development 1993;118:777-784.
46. Lin J, Adam RM, Santiestevan E, Freeman MR: The phosphatidylinositol 3′-kinase pathway is a dominant growth factor-activated cell survival pathway in LNCaP human prostate carcinoma cells. Cancer Res 1999;59:2891-2897.