Suppressive effect of phosphodiesterase type 4 inhibition on systemic inflammatory responses after cardiopulmonary bypass

Journal of Artificial Organs

Volumn 9, Issue 3, 2006, Pages 144-148

  Hamamoto, Masaki ^a   Suga, Michiharu ^a   Takahashi, Yuzo ^a   Sato, Yukio ^b   Inamori, Shuji ^a   Yagihara, Toshikatsu ^a   Nakatani, Takeshi ^a   Kitamura, Soichiro ^a  

^a NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

^b JICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

Cardiopulmonary bypass; Phosphodiesterase type 4 inhibitor; Rat; Systemic inflammatory response

Indexed keywords

CD11B ANTIGEN; ELASTASE; INTERLEUKIN 1BETA; MACROPHAGE INFLAMMATORY PROTEIN 2; PHOSPHODIESTERASE IV INHIBITOR; ROLIPRAM; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN EXPRESSION; ARTICLE; CARDIOPULMONARY BYPASS; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENZYME BLOOD LEVEL; FLOW CYTOMETRY; IMMUNOSUPPRESSIVE TREATMENT; MALE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RAT; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; TREATMENT OUTCOME;

3',5'-CYCLIC-AMP PHOSPHODIESTERASES; 3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE; ANIMALS; ANTIGENS, CD11B; CARDIOPULMONARY BYPASS; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 4; CYTOKINES; DISEASE MODELS, ANIMAL; MALE; NEUTROPHILS; PHOSPHODIESTERASE INHIBITORS; RATS; ROLIPRAM; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; TREATMENT OUTCOME;

EID: 33749034699     PISSN: 14347229     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10047-006-0335-2     Document Type: Article

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