Pathophysiology of cutaneous lupus erythematosus - Novel aspects

Rheumatology

Volumn 45, Issue SUPPL. 3, 2006, Pages

  Kuhn, Annegret ^a,b   Krammer, P H ^b   Kolb Bachofen, V ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; CHEMOKINE RECEPTOR CCR4; CHEMOKINE RECEPTOR CXCR3; CXCL11 CHEMOKINE; CXCL9 CHEMOKINE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INDUCIBLE NITRIC OXIDE SYNTHASE; THYMUS AND ACTIVATION REGULATED CHEMOKINE; UNCLASSIFIED DRUG;

APOPTOSIS; CD4+ CD25+ T LYMPHOCYTE; DISEASE CLASSIFICATION; ENVIRONMENTAL FACTOR; HUMAN; INFLAMMATION; LIGHT EXPOSURE; PATHOGENESIS; PATHOPHYSIOLOGY; PHOTOSENSITIVITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROVOCATION TEST; REGULATORY T LYMPHOCYTE; REVIEW; SKIN LUPUS ERYTHEMATOSUS; TISSUE INJURY; ULTRAVIOLET RADIATION;

APOPTOSIS; HUMANS; LUPUS ERYTHEMATOSUS, CUTANEOUS; NITRIC OXIDE SYNTHASE TYPE II; ULTRAVIOLET RAYS;

EID: 33749023575     PISSN: 14620324     EISSN: 14620332     Source Type: Journal    
DOI: 10.1093/rheumatology/kel284     Document Type: Review

References (20)

1. Kuhn A, Sontheimer RD, Ruzicka T. Classification of cutaneous lupus erythematosus. In: Kuhn A, Lehmann P, Ruzicka T, eds. Cutaneous Lupus Erythematosus. Heidelberg: Springer, 2004;53-8.
2. Kuhn A, Beissert S. Photosensitivity in lupus erythematosus. Autoimmun 2005;38:519-29.
3. Albrecht J, Berlin JA, Bravermann IM et al. Dermatology position paper on the revision of the 1982 ACR criteria for systemic lupus erythematosus. Lupus 2004;13:839-49.
4. Kuhn A, Sonntag M, Richter-Hintz D et al. Phototesting in lupus erythematosus: A 15-year experience. J Am Acad Dermatol 2001;45:86-95.
5. Stern RS, Docken W. An exacerbation of SLE after visiting a tanning salon. JAMA 1986;255:3120.
6. Stege H, Budde MA, Grether-Beck S, Richard A, Rougier A, Krutmann J. Evaluation of the capacity of sunscreens to photoprotect lupus erythematosus patients by employing the photoprovocation test. Eur J Dermatol 2002;12:VII-IX.
7. Kuhn A, Herrmann M, Kleber S et al. Accumulation of apoptotic cells in the epidermis of patients with cutaneous lupus erythematosus after ultraviolet irradiation. Arthritis Rheum 2006;54:939-50.
8. Baumann I, Kolowos W, Voll RE et al. Impaired uptake of apoptotic cells into tingible body macrophages in germinal centers of patients with systemic lupus erythematosus. Arthritis Rheum 2002;46:191-201.
9. Gaipl US, Kuhn A, Sheriff A et al. Clearance of apoptotic cells in human SLE. Curr Dir Autoimmun 2006;9:173-87.
10. Suschek CV, Krischel V, Bruch-Gerharz D et al. Nitric oxide fully protects against UVA-induced apoptosis in tight correlation with Bcl-2 up-regulation. J Biol Chem 1999;274:6130-7.
11. Weller R, Schwentker A, Billiar TR, Vodovotz Y. Autologous nitric oxide protects mouse and human keratinocytes from ultraviolet B radiation-induced apoptosis. Am J Physiol Cell Physiol 2003;284:C1140-8.
12. Kuhn A, Fehsel K, Lehmann P, Krutmann J, Ruzicka T, Kolb-Bachofen V. Aberrant timing in epidermal expression of inducible nitric oxide synthase after UV irradiation in cutaneous lupus erythematosus. J Invest Dermatol 1998;111:149-53.
13. Belmont HM, Levartovsky D, Goel A et al. Increased nitric oxide production accompanied by the up-regulation of inducible nitric oxide synthase in vascular endothelium from patients with systemic lupus erythematosus. Arthritis Rheum 1997;40:1810-6.
14. Lopez-Nevot MA, Ramal L, Jimenez-Alonso J, Martin J. The inducible nitric oxide synthase promoter polymorphism does not confer susceptibility to systemic lupus erythematosus. Rheumatology 2003;42:113-6.
15. + regulatory T cells in immunological tolerance to self and non-self. Nat Immunol 2005;6:345-52.
16. Crispin JC, Martinez A, Alcocer-Varela J. Quantification of regulatory T cells in patients with systemic lupus erythematosus. J Autoimmun 2003;21:273-6.
17. + regulatory T-cell population and autoantibody levels in paediatric patients with systemic lupus erythematosus. Immunology 2006;117:280-6.
18. Miyara M, Amoura Z, Parizot C et al. Global natural regulatory T cell depletion in active systemic lupus erythematosus. J Immunol 2005;175:8392-400.
19. Meller S, Winterberg F, Gilliet M et al. Ultraviolet radiation-induced injury, chemokines, and leukocyte recruitment: An amplification cycle triggering cutaneous lupus erythematosus. Arthritis Rheum 2005;52:1504-16.
20. Wenzel J, Henze S, Worenkamper E et al. Role of the chemokine receptor CCR4 and its ligand thymus- and activation-regulated chemokine/CCL17 for lymphocyte recruitment in cutaneous lupus erythematosus. J Invest Dermatol 2005;124:1241-8.