Fluorescein isothiocyanate labelled bovine serum albumin (FITC-BSA) as a model protein drug: Opportunities and drawbacks

Pharmazie

Volumn 61, Issue 9, 2006, Pages 770-774

  Wischke, C ^a   Borchert, H H ^a  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BOVINE SERUM ALBUMIN; DRUG VEHICLE; FLUORESCEIN ISOTHIOCYANATE;

ARTICLE; CELL CULTURE; DENDRITIC CELL; DRUG RELEASE; FLUORESCENCE SPECTROSCOPY; GEL PERMEATION CHROMATOGRAPHY; HUMAN; HUMAN CELL; MASS SPECTROMETRY; MICROPARTICLE ENZYME IMMUNOASSAY; PROTEIN DETERMINATION; PROTEIN HYDROLYSIS; PROTEIN LOCALIZATION; TISSUE CULTURE;

DENDRITIC CELLS; DRUG COMPOUNDING; ENDOPEPTIDASE K; FLUORESCEIN-5-ISOTHIOCYANATE; FLUORESCENT DYES; FREEZE DRYING; HUMANS; HYDROLYSIS; MOLECULAR WEIGHT; MONOCYTES; NANOSTRUCTURES; PHARMACEUTICAL PREPARATIONS; PROTEINS; REFERENCE STANDARDS; SERUM ALBUMIN, BOVINE; TRYPSIN;

EID: 33749021944     PISSN: 00317144     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Bilati U, Allémann E, Doelker E (2005a) Strategic approaches for overcoming peptide and protein instability within biodegradable nano- and microparticles. Eur J Pharm Biopharm 59: 375-388.
2. Bilati U, Allémann E, Doelker E (2005b) Poly(D,L-lactide-co- glycolide) protein-loaded nanoparticles prepared by the double emulsion method - processing and formulation issues for enhanced entrapment efficiency. J Microencapsul 22: 205-214.
3. Carter DC, Ho JX (1994) Structure of serum albumin. Adv Protein Chem 45: 153-203.
4. Castellanos IJ, Cuadrado WL, Griebenow K (2001) Prevention of structural perturbations and aggregation upon encapsulation of bovine serum albumin into poly(lactide-co-glycolide) microspheres using the solid-in-oil-in-water technique. Pharm Pharmacol 53: 1099-1107.
5. Chen RF, Knutson JR (1988) Mechanism of fluorescence concentration quenching of carbofluorescein in liposomes: energy transfer to nonfluorescent dimers. Anal Biochem 172: 61-77.
6. Cohen S, Yoshioka T, Lucarelli M, Hwang LH, Langer R (1991) Controlled delivery systems for proteins based on poly(lactic/glycolic acid) microspheres. Pharm Res 8: 713-720.
7. Conway BR, Alpar HO (1996) Double emulsion microencapsulation of proteins as model antigens using polylactide polymers: Effect of emulsifier on the microsphere characteristics and release kinetics. Eur J Pharm Biopharm 42: 42-48.
8. Der-Balian GP, Kameda N, Rowley GL (1988) Fluorescein labeling of Fab' while preserving single thiol. Anal Biochem 173: 59-63.
9. Förster T, König E (1957) Absorptionsspektren und Fluoreszenzeigenschaften konzentrierter Lösungen organischer Stoffe. Z Elektrochemie 61: 344-348.
10. Folta-Stogniew E, Williams KR (1999) Determination of molecular masses of proteins in solution: Implementation of an HPLC size exclusion chromatography and laser scattering service in a core laboratory. J Biomol Tech 10: 51-63
11. Frangione-Beebe M, Rose RT, Kaumaya PTP, Schwendeman SP (2001) Microencapsulation of a synthetic peptide epitope for HTLV-1 in biodegradable poly(D,L-lactide-co-glycolide) microspheres using a novel encapsulation technique. J Microencapsul 18: 663-677.
12. th ed., Molecular Probes, Eugene, USA
13. Hirayama K, Akashi S, Furuya M, Fukuhara K (1990) Rapid confirmation and revision of the primary structure of bovine serum albumin by ESIMS and Frit-FAB LC/MS. Biochem Biophys Res Commun 173: 639-646.
14. Hunter AK, Carta G (2001) Effects of bovine serum albumin heterogeneity on frontal analysis with anion-exchange media. J Chromatogr A 937: 13-19.
15. Janatova J, Fuller JK, Hunter MJ (1968) The heterogeneity of bovine albumin with respect to sulfhydryl and dimer content. J Biol Chem 243: 3612-3622.
16. Jiang G, Woo BH, Kang F, Singh J, DeLuca PP (2002) Assessment of protein release kinetics, stability and protein polymer interaction of lysozyme encapsulated poly(D,L-lactide-co-glycolide) microspheres. J Control Release 79: 137-145.
17. Kawski A (1983) Excitation energy transfer and its manifestation in isotropic media. Photochem Photobiol 38: 497-508.
18. nd ed., New York
19. Li L, Schwendeman SP (2005) Mapping neutral microclimate pH in PLGA microspheres. J Control Release 101: 163-173.
20. Mäder K, Bittner B, Li Y, Wohlauf W, Kissel T (1998) Monitoring microviscosity and microacidity of the albumin environment inside degrading microparticles from poly(lactide-co-glycolide) (PLG) or ABA-triblock polymers containing hydrophobic poly(lactide-co-glycolide) A blocks and hydrophilic poly(ethyleneoxide) B blocks. Pharm Res 15: 787-793.
21. Sah H (1999) Stabilization of proteins against methylene chlorid/water interface-induced denaturation and aggregation. J Control Release 58: 143-151.
22. Wilson WD, Foster JF (1971) Conformation-dependent limited proteolysis of bovine plasma albumin by an enzyme present in commercial albumin preparations. Biochemistry 10: 1772-1780.
23. Wischke C, Borhert H-H (2006) Influence of the primary emulsification procedure on the characteristics of small protein loaded PLGA microparticles for antigen delivery. J Microencapsul in press.
24. Wischke C, Lorenzen D, Zimmermann J, Borchert H-H (2006) Preparation of protein loaded poly(D,L-lactide co glycolide) microparticles for the antigen delivery to dendritic cells using a static micromixer. Eur J Pharm Biopharm 62: 247-253.