Preclinical acute toxicity studies and dosimetry estimates of the novel sigma-1 receptor radiotracer, [18F]SFE

Molecular Imaging and Biology

Volumn 8, Issue 5, 2006, Pages 284-291

  Waterhouse, Rikki N ^a,b   Zhao, Jun ^a   Stabin, Michael G ^c   Ng, Hanna ^d   Schindler Horvat, Janice ^d   Chang, Raymond C ^a   Mirsalis, Jon C ^d  

^a NEW YORK STATE PSYCHIATRIC INSTITUTE   (United States)

^b Och Spine at New York Presbyterian Hospitals   (United States)

^c VANDERBILT UNIVERSITY   (United States)

^d SRI INTERNATIONAL   (United States)

Author keywords

Dosimetry; PET; Radiotracer; Sigma receptor; Toxicity

Indexed keywords

1 (2 FLUOROETHYL) 4 [(4 CYANOPHENOXY)METHYL]PIPERIDINE F 18; RADIOLIGAND; SIGMA 1 OPIATE RECEPTOR; TRACER; UNCLASSIFIED DRUG;

ACUTE TOXICITY; ADRENAL GLAND; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BONE TISSUE; BRAIN TISSUE; CONTROLLED STUDY; DOG; DOSIMETRY; DRUG APPROVAL; DRUG DISTRIBUTION; DRUG SAFETY; FEMALE; LIVER; LUNG PARENCHYMA; MALE; MULTIPLE DRUG DOSE; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RABBIT; RADIATION DOSE DISTRIBUTION; RADIATION EXPOSURE; RAT; SINGLE DRUG DOSE; SPLEEN; TISSUE DISTRIBUTION; WHOLE BODY RADIATION;

ANIMALS; CARDIOVASCULAR SYSTEM; DOGS; DRUG EVALUATION, PRECLINICAL; FEMALE; MALE; MAXIMUM TOLERATED DOSE; PIPERIDINES; POSITRON-EMISSION TOMOGRAPHY; RABBITS; RADIATION DOSAGE; RADIOACTIVE TRACERS; RECEPTORS, SIGMA; TISSUE DISTRIBUTION;

CANIS FAMILIARIS; ORYCTOLAGUS CUNICULUS; RODENTIA;

EID: 33748989843     PISSN: 15361632     EISSN: 18602002     Source Type: Journal    
DOI: 10.1007/s11307-006-0056-1     Document Type: Article

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