Maize meal predisposes to endemic squamous cancer of the oesophagus in Africa: Breakdown of esterified linoleic acid to the free form in stored meal leads to increased intragastric PGE2 production and a low-acid reflux

Medical Hypotheses

Volumn 67, Issue 6, 2006, Pages 1431-1436

  Sammon, A M ^a   Iputo, J E ^b  

^a GLOUCESTERSHIRE ROYAL HOSPITAL   (United Kingdom)

^b WALTER SISULU UNIVERSITY   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; CORN OIL; LINOLEIC ACID; OMEGA 3 FATTY ACID; OMEGA 6 FATTY ACID; PROSTAGLANDIN E2; RIBOFLAVIN;

ARTICLE; CANCER INCIDENCE; CANCER RISK; CANCER SUSCEPTIBILITY; CARCINOGENESIS; DIET SUPPLEMENTATION; DUODENOGASTRIC REFLUX; ENDEMIC DISEASE; ESOPHAGUS CARCINOMA; ESTERIFICATION; FAT INTAKE; FOOD INTAKE; GASTROESOPHAGEAL REFLUX; GEOGRAPHIC DISTRIBUTION; HEARTBURN; HUMAN; HYPOTHESIS; KWASHIORKOR; LOWER ESOPHAGUS SPHINCTER; MAIZE; NONHUMAN; NUTRIENT CONTENT; NUTRITIONAL DEFICIENCY; PREDICTION; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; REFLUX ESOPHAGITIS; RIBOFLAVIN DEFICIENCY; RISK ASSESSMENT; SQUAMOUS CELL CARCINOMA; STOMACH ACID SECRETION; STOMACH CONTENT; STOMACH JUICE; STOMACH PH; VOMITING;

AFRICA; CARCINOMA, SQUAMOUS CELL; CORN OIL; DIET; DINOPROSTONE; DISEASE SUSCEPTIBILITY; ENDEMIC DISEASES; ESOPHAGEAL NEOPLASMS; FATTY ACIDS, NONESTERIFIED; GASTROESOPHAGEAL REFLUX; HUMANS; HYDROGEN-ION CONCENTRATION; INCIDENCE; LINOLEIC ACID; MODELS, BIOLOGICAL; ZEA MAYS;

ZEA MAYS;

EID: 33748982368     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mehy.2006.05.037     Document Type: Article

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