메뉴 건너뛰기




Volumn 39, Issue 10, 2006, Pages 1022-1027

Determination of free and total carnitine in plasma by an enzymatic reaction and spectrophotometric quantitation spectrophotometric determination of carnitine

Author keywords

Carnitine acetyltransferase; Enzymatic assay; Free carnitine; Plasma; Spectrophotometry; Total carnitine

Indexed keywords

ACETYL COENZYME A; ACYLCARNITINE; ACYLTRANSFERASE; CARNITINE; COENZYME A;

EID: 33748978227     PISSN: 00099120     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clinbiochem.2006.06.005     Document Type: Article
Times cited : (36)

References (34)
  • 2
    • 10644250580 scopus 로고    scopus 로고
    • Carnitine deficiency disorders in children
    • Stanley C.A. Carnitine deficiency disorders in children. Ann. N. Y. Acad. Sci. 1033 (2004) 42-51
    • (2004) Ann. N. Y. Acad. Sci. , vol.1033 , pp. 42-51
    • Stanley, C.A.1
  • 3
    • 0037942907 scopus 로고    scopus 로고
    • Carnitine metabolism and deficit-when supplementation is necessary?
    • Evangeliou A., and Vlassopoulos D. Carnitine metabolism and deficit-when supplementation is necessary?. Curr. Pharm. Biotechnol. 4 (2003) 211-219
    • (2003) Curr. Pharm. Biotechnol. , vol.4 , pp. 211-219
    • Evangeliou, A.1    Vlassopoulos, D.2
  • 4
    • 0028850504 scopus 로고
    • Primary and secondary carnitine deficiency syndromes
    • Pons R., and DeVivo D.C. Primary and secondary carnitine deficiency syndromes. J. Child Neurol. 10 (1995) 2S8-2S21
    • (1995) J. Child Neurol. , vol.10
    • Pons, R.1    DeVivo, D.C.2
  • 5
    • 0032953645 scopus 로고    scopus 로고
    • Primary systemic carnitine deficiency is caused by mutations in a gene encoding sodium ion-dependent carnitine transporter
    • Nezu J., Tamai I., Oku A., Ohashi R., Yabuuchi H., Hashimoto N., et al. Primary systemic carnitine deficiency is caused by mutations in a gene encoding sodium ion-dependent carnitine transporter. Nat. Genet. 21 (1999) 91-94
    • (1999) Nat. Genet. , vol.21 , pp. 91-94
    • Nezu, J.1    Tamai, I.2    Oku, A.3    Ohashi, R.4    Yabuuchi, H.5    Hashimoto, N.6
  • 6
    • 0036197207 scopus 로고    scopus 로고
    • Fatty acid oxidation disorders
    • Rinaldo P., and Matern D. Fatty acid oxidation disorders. Annu. Rev. Physiol. 64 (2002) 477-502
    • (2002) Annu. Rev. Physiol. , vol.64 , pp. 477-502
    • Rinaldo, P.1    Matern, D.2
  • 7
    • 0037385059 scopus 로고    scopus 로고
    • The role of carnitine in normal and altered fatty acid metabolism
    • Hoppel C. The role of carnitine in normal and altered fatty acid metabolism. Am. J. Kidney Dis. 41 (2003) S4-S12
    • (2003) Am. J. Kidney Dis. , vol.41
    • Hoppel, C.1
  • 9
    • 0028843226 scopus 로고
    • Carnitine deficiency during valproic acid treatment
    • Van Wouwe J.P. Carnitine deficiency during valproic acid treatment. Int. J. Vitam. Nutr. Res. 65 (1995) 211-214
    • (1995) Int. J. Vitam. Nutr. Res. , vol.65 , pp. 211-214
    • Van Wouwe, J.P.1
  • 11
    • 0015305639 scopus 로고
    • A method for the determination of carnitine in the picomole range
    • Cederblad G., and Lindstedt S. A method for the determination of carnitine in the picomole range. Clin. Chim. Acta 37 (1972) 235-243
    • (1972) Clin. Chim. Acta , vol.37 , pp. 235-243
    • Cederblad, G.1    Lindstedt, S.2
  • 12
    • 33748962639 scopus 로고
    • An improved and simplified radioisotopic assay for the determination of free and esterified carnitine
    • McGarry J., and Foster D. An improved and simplified radioisotopic assay for the determination of free and esterified carnitine. J. Lipid Res. 22 (1976) 1589-1592
    • (1976) J. Lipid Res. , vol.22 , pp. 1589-1592
    • McGarry, J.1    Foster, D.2
  • 13
    • 0025350370 scopus 로고
    • Carnitine: determination of total carnitine using radioenzymatic assay
    • Borum P.R. Carnitine: determination of total carnitine using radioenzymatic assay. J. Nutr. Biochem. 1 (1990) 111-114
    • (1990) J. Nutr. Biochem. , vol.1 , pp. 111-114
    • Borum, P.R.1
  • 14
    • 0027479739 scopus 로고
    • Carnitine measurement in liver, muscle tissue, and blood in normal subjects
    • Harper P., Wadström C., and Cederblad G. Carnitine measurement in liver, muscle tissue, and blood in normal subjects. Clin. Chem. 39 4 (1993) 592-599
    • (1993) Clin. Chem. , vol.39 , Issue.4 , pp. 592-599
    • Harper, P.1    Wadström, C.2    Cederblad, G.3
  • 15
    • 2442474285 scopus 로고    scopus 로고
    • A high performance liquid chromatographic method for the measurement of total carnitine in human plasma and urine
    • McEntire C.J., Lever M., and Storer M.K. A high performance liquid chromatographic method for the measurement of total carnitine in human plasma and urine. Clin. Chim. Acta 344 (2004) 123-130
    • (2004) Clin. Chim. Acta , vol.344 , pp. 123-130
    • McEntire, C.J.1    Lever, M.2    Storer, M.K.3
  • 16
    • 0026488346 scopus 로고
    • Determination of free carnitine and total carnitine in human urine: derivation with 4′-bromophenacyl trifluoromethanesulfonate and high performance liquid chromatography
    • Minkler P.E., and Hoppel C.L. Determination of free carnitine and total carnitine in human urine: derivation with 4′-bromophenacyl trifluoromethanesulfonate and high performance liquid chromatography. Clin. Chim. Acta 212 (1992) 55-64
    • (1992) Clin. Chim. Acta , vol.212 , pp. 55-64
    • Minkler, P.E.1    Hoppel, C.L.2
  • 17
    • 0027312948 scopus 로고
    • Quantification of free carnitine, individual short- and medium-chain acylcarnitines, and total carnitine in plasma by high-performance liquid chromatography
    • Minkler P.E., and Hoppel C.L. Quantification of free carnitine, individual short- and medium-chain acylcarnitines, and total carnitine in plasma by high-performance liquid chromatography. Anal. Biochem. 212 (1993) 510-518
    • (1993) Anal. Biochem. , vol.212 , pp. 510-518
    • Minkler, P.E.1    Hoppel, C.L.2
  • 18
    • 0037596765 scopus 로고    scopus 로고
    • Rapid liquid chromatography-electroespray tandem mass spectrometry method for the serum free and total carnitine
    • Ho C.S., Cheng B.S., and Lam C.W. Rapid liquid chromatography-electroespray tandem mass spectrometry method for the serum free and total carnitine. Clin. Chem. 49 (2003) 1189-1191
    • (2003) Clin. Chem. , vol.49 , pp. 1189-1191
    • Ho, C.S.1    Cheng, B.S.2    Lam, C.W.3
  • 19
    • 0034113953 scopus 로고    scopus 로고
    • Assay for free and total carnitine in human plasma using tandem mass spectrometry
    • Stevens R.D., Hillman S.L., Worthy S., Sanders D., and Millington D.S. Assay for free and total carnitine in human plasma using tandem mass spectrometry. Clin. Chem. 46 (2000) 727-729
    • (2000) Clin. Chem. , vol.46 , pp. 727-729
    • Stevens, R.D.1    Hillman, S.L.2    Worthy, S.3    Sanders, D.4    Millington, D.S.5
  • 20
    • 0036863339 scopus 로고    scopus 로고
    • Plasma free and total carnitine measured in children by tandem mass spectrometry
    • Osorio J.H., and Pourfarzam M. Plasma free and total carnitine measured in children by tandem mass spectrometry. Br. J. Med. Biol. Res. 35 (2002) 1171-1265
    • (2002) Br. J. Med. Biol. Res. , vol.35 , pp. 1171-1265
    • Osorio, J.H.1    Pourfarzam, M.2
  • 21
    • 22044456848 scopus 로고    scopus 로고
    • Rapid measurement of plasma acylcarnitines by liquid chromatography-tandem mass spectrometry without derivatization
    • Ghoshal A.K., Guo T., Soukhova N., and Soldin S.J. Rapid measurement of plasma acylcarnitines by liquid chromatography-tandem mass spectrometry without derivatization. Clin. Chim. Acta 358 (2005) 104-112
    • (2005) Clin. Chim. Acta , vol.358 , pp. 104-112
    • Ghoshal, A.K.1    Guo, T.2    Soukhova, N.3    Soldin, S.J.4
  • 22
    • 0342315176 scopus 로고
    • Enzymological determination of free carnitine concentrations in rat tissues
    • Marquis N.R., and Fritz I.B. Enzymological determination of free carnitine concentrations in rat tissues. J. Lipid Res. 5 (1964) 184-187
    • (1964) J. Lipid Res. , vol.5 , pp. 184-187
    • Marquis, N.R.1    Fritz, I.B.2
  • 23
    • 0026480518 scopus 로고
    • Automated analysis for free and short-chain acylcarnitine in plasma with a centrifugal analyzer
    • Roe D.S., Terada N., and Millington D.S. Automated analysis for free and short-chain acylcarnitine in plasma with a centrifugal analyzer. Clin. Chem. 38 11 (1992) 2215-2220
    • (1992) Clin. Chem. , vol.38 , Issue.11 , pp. 2215-2220
    • Roe, D.S.1    Terada, N.2    Millington, D.S.3
  • 25
    • 0022409614 scopus 로고
    • Determination of l-carnitine in serum, and implementation on the ABA-100 and CentrifiChem 600
    • Rodriguez-Segade S., Alonso dela Peña C., Paz J.M., and del Río R. Determination of l-carnitine in serum, and implementation on the ABA-100 and CentrifiChem 600. Clin. Chem. 31 5 (1985) 754-757
    • (1985) Clin. Chem. , vol.31 , Issue.5 , pp. 754-757
    • Rodriguez-Segade, S.1    Alonso dela Peña, C.2    Paz, J.M.3    del Río, R.4
  • 26
    • 0031949339 scopus 로고    scopus 로고
    • Determination of free and total carnitine with a random-access chemistry analyzer
    • Wan L., and Hubbard R.W. Determination of free and total carnitine with a random-access chemistry analyzer. Clin. Chem. 44 4 (1998) 810-816
    • (1998) Clin. Chem. , vol.44 , Issue.4 , pp. 810-816
    • Wan, L.1    Hubbard, R.W.2
  • 27
    • 25644437116 scopus 로고    scopus 로고
    • Determination of total and free plasma carnitine concentrations on the Dade Behring Dimension RxL: integrated chemistry system
    • Ghoshal A.K., and Soldin S.J. Determination of total and free plasma carnitine concentrations on the Dade Behring Dimension RxL: integrated chemistry system. Clin. Chim. Acta 361 (2005) 80-85
    • (2005) Clin. Chim. Acta , vol.361 , pp. 80-85
    • Ghoshal, A.K.1    Soldin, S.J.2
  • 28
    • 0025092356 scopus 로고
    • Rapid spectrophotometric determination of plasma carnitine concentrations
    • Maeda J., and Dubrick S.J. Rapid spectrophotometric determination of plasma carnitine concentrations. JPEN J. Parenter Enteral Nutr. 14 (1990) 527-532
    • (1990) JPEN J. Parenter Enteral Nutr. , vol.14 , pp. 527-532
    • Maeda, J.1    Dubrick, S.J.2
  • 29
    • 0028349194 scopus 로고
    • Carnitine determination by an enzymatic cycling method with carnitine dehydrogenase
    • Takahashi M., Ueda S., Misaki H., Sugiyama N., Matsumoto K., Matsuo N., et al. Carnitine determination by an enzymatic cycling method with carnitine dehydrogenase. Clin. Chem. 40 5 (1994) 817-821
    • (1994) Clin. Chem. , vol.40 , Issue.5 , pp. 817-821
    • Takahashi, M.1    Ueda, S.2    Misaki, H.3    Sugiyama, N.4    Matsumoto, K.5    Matsuo, N.6
  • 30
    • 0001025498 scopus 로고
    • The distribution of carnitine, acetylcarnitine and carnitine acetyltransferase in rat tissues
    • Marquis N.R., and Fritz I.B. The distribution of carnitine, acetylcarnitine and carnitine acetyltransferase in rat tissues. J. Biol. Chem. 240 (1965) 2193-2196
    • (1965) J. Biol. Chem. , vol.240 , pp. 2193-2196
    • Marquis, N.R.1    Fritz, I.B.2
  • 31
    • 0024324605 scopus 로고
    • A spectrophotometric method for the determination of free and esterified carnitine
    • Schäfer J., and Reichmann H. A spectrophotometric method for the determination of free and esterified carnitine. Clin. Chim. Acta 182 (1989) 87-94
    • (1989) Clin. Chim. Acta , vol.182 , pp. 87-94
    • Schäfer, J.1    Reichmann, H.2
  • 32
    • 0015590324 scopus 로고
    • Serum carnitine. An index of muscle destruction in man
    • DiMauro S., Scott C.C., Penn S.A., and Rowland L.P. Serum carnitine. An index of muscle destruction in man. Arch. Neurol. 28 (1973) 186-190
    • (1973) Arch. Neurol. , vol.28 , pp. 186-190
    • DiMauro, S.1    Scott, C.C.2    Penn, S.A.3    Rowland, L.P.4
  • 33
    • 0021361415 scopus 로고
    • Sources of error in determinations of carnitine and acylcarnitine in plasma
    • Fishlock R.C., Bieber L.L., and Snoswell A.M. Sources of error in determinations of carnitine and acylcarnitine in plasma. Clin. Chem. 30 (1984) 316-318
    • (1984) Clin. Chem. , vol.30 , pp. 316-318
    • Fishlock, R.C.1    Bieber, L.L.2    Snoswell, A.M.3
  • 34
    • 0345930501 scopus 로고    scopus 로고
    • Tandem mass spectrometry in clinical diagnosis
    • Blau N., Duran M., Blaskovics M.E., and Gibson K.M. (Eds), Springer-Verlag, Berlin
    • Millington D.S. Tandem mass spectrometry in clinical diagnosis. In: Blau N., Duran M., Blaskovics M.E., and Gibson K.M. (Eds). Physician's guide to the laboratory diagnosis of metabolic diseases. second ed. (2003), Springer-Verlag, Berlin 57-75
    • (2003) Physician's guide to the laboratory diagnosis of metabolic diseases. second ed. , pp. 57-75
    • Millington, D.S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.