Damage to the human cerebellum from prenatal alcohol exposure: The anatomy of a simple biometrical explanation

Anatomical Record - Part B New Anatomist

Volumn 289, Issue 5, 2006, Pages 195-209

  Bookstein, Fred L ^a,b,d   Streissguth, Ann P ^c   Connor, Paul D ^c   Sampson, Paul D ^c  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF VIENNA   (Austria)

^c UW ^*

^d UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

Birth defects; Cerebellum; Fetal alcohol spectrum disorders; Magnetic resonance imaging; Medical image analysis; Morphometrics

Indexed keywords

ALCOHOL;

ALLOMETRY; ARTICLE; BIOMETRY; BIRTH DEFECT; BRAIN DEVELOPMENT; CEREBELLUM; COMPUTER PROGRAM; FETAL ALCOHOL SYNDROME; FETUS; HUMAN; MORPHOMETRICS; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; PRENATAL EXPOSURE; PRIORITY JOURNAL; STATISTICAL ANALYSIS; TERATOLOGY; THREE DIMENSIONAL IMAGING;

ADOLESCENT; ADULT; ANTHROPOMETRY; CEREBELLUM; DISCRIMINANT ANALYSIS; ETHANOL; FEMALE; FETAL ALCOHOL SYNDROME; HUMANS; IMAGING, THREE-DIMENSIONAL; MALE; MULTIVARIATE ANALYSIS; PREGNANCY;

EID: 33748929268     PISSN: 15524906     EISSN: None     Source Type: Journal    
DOI: 10.1002/ar.b.20114     Document Type: Article

References (38)

1. Autti-Ramo I, Autti T, Korkman M, Kettunen S, Salonen O, Valanne L. 2002. MRI findings in children with school problems who had been exposed prenatally to alcohol. Dev Med Child Neurol 44:98-106.
2. Blackith RA, Reyment RE. 1971. Multivariate morphometrics. London: Academic Press.
3. Bonthius DJ, Karacay B, Dai D, Hutton A, Pantazis NJ. 2004. The NO-cGMP-PKG pathway plays an essential role in the acquisition of ethanol resistance by cerebellar granule neurons. Neurotoxicol Teratol 26:47-57.
4. Bookstein FL. 1991. Morphometric tools for landmark data. New York: Cambridge University Press.
5. Bookstein FL, Schaefer K, Prossinger H, et al. 1999. Comparing frontal cranial profiles in archaic and modern Homo by morphometric analysis. Anat Rec (New Anat) 257B:217-224.
6. Bookstein FL, Sampson PD, Connor PD, Streissguth AP. 2002a. The midline corpus callosum is a neuroanatomical focus of fetal alcohol damage. Anat Rec (New Anat) 269B:162-174.
7. Bookstein FL, Streissguth AP, Sampson PD, Connor PD, Barr HM. 2002b. Corpus callosum shape and neuropsychological deficits in adult males with heavy fetal alcohol exposure. NeuroImage 15:233-251.
8. Bookstein FL, Sampson PD. 2005. Suggested statistical standards for NTT manuscripts: notes from two of your reviewers. Neurotoxicol Teratol 27:207-415.
9. Bookstein FL, Connor PD, Covell K, Barr HM, Gleason CA, Sze RW, McBroom JA, Streissguth AP. 2005. Preliminary evidence that prenatal alcohol damage may be visible in averaged unwarped ultrasound images of the neonatal human corpus callosum. Alcohol 36:151-160.
10. Bookstein FL. 2006. My unexpected journey in applied biomathematics. Biol Theory 1:65-75.
11. Chen WJA, Maier SE, Parnell SE, West JR. 2003. Alcohol and the developing brain: neuroanatomical studies. Alcohol Res Health 27:174-180.
12. Connor PD, Sampson PD, Streissguth AP, Bookstein FL, Barr HM. 2006. Effects of prenatal alcohol exposure on fine motor coordination and balance: a study of two adult samples. Neuropsychologia 44:744-751.
13. Dikranian K, Qin YQ, Labruyere J, Nemmers B, Olney JW. 2005. Ethanol-induced neuroapoptosis in the developing rodent cerebellum and related brain stem structures. Dev Brain Res 155:1-13.
14. Dryden IL, Mardia KV. 1998. Statistical shape analysis. New York: John Wiley and Sons.
15. González-Burgos I, Alejandre-Gómez M. 2005. Cerebellar granule cell and Bergmann glial cell maturation in the rat is disrupted by pre- and post-natal exposure to moderate levels of alcohol. Int J Dev Neurosci 23:383-388.
16. Good PM. 2000. Permutation tests, 2nd ed. New York: Springer Verlag.
17. Goodlett CR, West JR. 1992. Fetal alcohol effects: rat model of alcohol exposure during the brain growth spurt. In: Zagon IS, Slotkin TA, editors. Maternal substance abuse and the developing nervous system. San Diego, CA: Academic Press. p 45-75.
18. Gould SJ. 1965. Allometry and size in ontogeny and phylogeny. Biol Rev 41:587-620.
19. Green JT. 2004. The effects of ethanol on the developing cerebellum and eyeblink classicalconditioning. Cerebellum 3:178-187.
20. Gunz P, Mitteroecker P, Bookstein FL. 2004. Semilandmarks in three dimensions. In: Slice DE, editor. Modern morphometrics in physical anthropology. New York: Kluwer Academic. p 73-98.
21. Huxley JS. 1932. Problems of relative growth. London: Methuen.
22. Koenderink J. 1990. Solid shape. Cambridge, MA: MIT Press.
23. Li Z, Miller MW, Luo J. 2002. Effects of prenatal exposure to ethanol on the cyclin-dependent kinase system in the developing rat cerebellum. Dev Brain Res 139:237-245.
24. Light KE, Brown DP, Newton BW, Belcher WM, Kane CJM. 2002. Ethanol-induced alterations of neurotrophin receptor expression on Purkinje cells in the neonatal rat cerebellum. Brain Res 924:871-881.
25. Martin R. 1928. Lehrbuch der Anthropologie in systematischer Darstellung mit besonderer Berücksichtigung der anthropologischen Methoden: für Studierende, Ärzte und Forschungsreisende. Jena: Gustav Fischer Verlag.
26. Mitteroecker P, Gunz P, Bernhard M, Schaefer K, Bookstein FL. 2004. Comparison of cranial ontogenetic trajectories among great apes and humans. J Hum Evol 46:679-697.
27. O'Hare ED, Kan E, Yoshii J, Mattson SN, Riley EP, Thompson PM, Toga AW, Sowell ER. 2005. Mapping cerebellar vermal morphology and cognitive correlates in prenatal alcohol exposure. NeuroReport 16:1285-1290.
28. Reyment RA, Jöreskög KG. 1993. Applied factor analysis in the natural sciences. New York: Cambridge University Press.
29. Riley EP, McGee CL, Sowell ER. 2004. Teratogenic effects of alcohol: a decade of brain imaging. Am J Med Genet 127C: 35-41.
30. Riley EP, McGee CL. 2005. Fetal alcohol spectrum disorders: an overview with emphasis on changes in brain and behavior. Exp Biol Med 230:357-365.
31. Sachse FB. 2004. Computational cardiology: modeling of anatomy, electrophysiology, and mechanics. New York: Springer Verlag.
32. Schmahmann J, Doyon J, Toga AW, Petrides M, Evans A. 2000. MRI atlas of the human cerebellum. San Diego, CA: Academic Press.
33. Siler-Marsiglio KI, Paiva M, Madorsky I, Pan Q, Shaw G, Heaton MB. 2005. Functional mechanisms of apoptosis-related proteins in neonatal rat cerebellum are differentially influenced by ethanol at postnatal days 4 and 7. J Neurosci Res 81:632-643.
34. Sowell ER, Jernigan TL, Mattson SN, Riley EP, Sobel DF, Jones KL. 1996. Abnormal development of the cerebellar vermis in children prenatally exposed to alcohol: size reduction in lobules I-V. Alc Clin Exp Res 20:31-34.
35. Sowell ER, Mattson SN, Thompson PM, Jernigan TL, Riley EP, Toga AW. 2001. Mapping callosal morphology and cognitive correlate: effects of heavy prenatal alcohol exposure. Neurology 57:235-244.
36. Streissguth AP. 1997. Fetal alcohol syndrome: a guide for families and communities. Baltimore, MD: Paul H. Brookes.
37. Sulik KK, Johnson MC, Webb MA. 1981. Fetal alcohol syndrome: Embryogenesis in a mouse model. Science 214:936-938.
38. West JR. 1986. Alcohol and brain development. New York: Oxford University Press.