Hypertrophic muscle fibers with fissures in power-lifters; fiber splitting or defect regeneration?

Histochemistry and Cell Biology

Volumn 126, Issue 4, 2006, Pages 409-417

  Eriksson, Anders ^a,b   Lindström, Mona ^a   Carlsson, Lena ^a   Thornell, Lars Eric ^a  

^a UMEÅ UNIVERSITY   (Sweden)

^b LULEÅ UNIVERSITY OF TECHNOLOGY   (Sweden)

Author keywords

Abortive regeneration; Anabolic steroids; Split fiber

Indexed keywords

ANABOLIC AGENT;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MECHANICAL STRESS; MUSCLE ATROPHY; MUSCLE BIOPSY; MUSCLE CELL; MUSCLE HYPERTROPHY; MUSCLE INJURY; MUSCLE REGENERATION; PRIORITY JOURNAL; SATELLITE CELL; SPORT; TRAPEZIUS MUSCLE; VASTUS LATERALIS MUSCLE;

ADULT; ANABOLIC AGENTS; HUMANS; HYPERTROPHY; IMMUNOHISTOCHEMISTRY; MALE; MUSCLE FIBERS; MUSCLE FIBERS, SKELETAL; MUSCLE, SKELETAL; REGENERATION; SELF ADMINISTRATION; STEROIDS; WEIGHT LIFTING;

EID: 33748923508     PISSN: 09486143     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00418-006-0176-3     Document Type: Article

References (40)

1. Alen M, Hakkinen K, Komi PV (1984) [Changes in muscle power production capacity in power athletes self-administering androgenic anabolic steroids]. Duodecim 100:1096-1104
2. Antonio J, Gonyea WJ (1993) Skeletal muscle fiber hyperplasia. Med Sci Sports Exerc 25:1333-1345
3. Aumailley M, Bruckner-Tuderman L, Carter WG, Deutzmann R, Edgar D, Ekblom P, Engel J, Engvall E, Hohenester E, Jones JC, Kleinman HK, Marinkovich MP, Martin GR, Mayer U, Meneguzzi G, Miner JH, Miyazaki K, Patarroyo M, Paulsson M, Quaranta V, Sanes JR, Sasaki T, Sekiguchi K, Sorokin LM, Talts JF, Tryggvason K, Uitto J, Virtanen I, von der Mark K, Wewer UM, Yamada Y, Yurchenco PD (2005) A simplified laminin nomenclature. Matrix Biol 24:326-332
4. Balaram SK, Agrawal DK, Allen RT, Kuszynski CA, Edwards JD (1997) Cell adhesion molecules and insulin-like growth factor-1 in vascular disease. J Vasc Surg 25:866-876
5. Bruusgaard JC, Liestol K, Ekmark M, Kollstad K, Gundersen K (2003) Number and spatial distribution of nuclei in the muscle fibres of normal mice studied in vivo. J Physiol 551:467-478
6. Carpenter S, Karpati G (2001) Pathology of skeletal muscle, 2nd edn. Oxford University Press, New York
7. Chou SM, Nonaka I (1977) Satellite cells and muscle regeneration in diseased human skeletal muscles. J Neurol Sci 34:131-145
8. Danon MJ, Carpenter S (1991) Myopathy with thick filament (myosin) loss following prolonged paralysis with vecuronium during steroid treatment. Muscle Nerve 14:1131-1139
9. Dubowitz V (1974) Muscle biopsy-technical and diagnostic aspects. Ann Clin Res 6:69-79
10. Dubowitz V (1985) Muscle biopsy, a practical approach, 2nd edn. The Lavenham Press, Lavenham
11. Dubowitz V, Gallup B, Witkowski J (1973) Normal and diseased muscle in tissue culture. J Physiol 231:61P-62P
12. Edgerton VR (1970) Morphology and histochemistry of the soleus muscle from normal and exercised rats. Am J Anat 127:81-87
13. Engel AG, Franzini-Armstrong C (2004) Myology, 3rd edn vol 1. McGraw-Hill, USA
14. Englander LL, Rubin LL (1987) Acetylcholine receptor clustering and nuclear movement in muscle fibers in culture. J Cell Biol 104:87-95
15. Eriksson A, Kadi F, Malm C, Thornell LE (2005) Skeletal muscle morphology in power-lifters with and without anabolic steroids. Histochem Cell Biol 124:1-9
16. Freed DL, Banks AJ, Longson D, Burley DM (1975) Anabolic steroids in athelics: crossover double-blind trial on weightlifters. Br Med J 2:471-473
17. Gallanti A, Prelle A, Chianese L, Barbieri S, Jann S, Schiaffino S, Comini A, Scarpini E, Pellegrini G, Moggio M, et al. (1992) Congenital myopathy with type 2A muscle fiber uniformity and smallness. Neuropediatrics 23:10-13
18. Gonyea WJ (1980) Muscle fiber splitting in trained and untrained animals. Exerc Sport Sci Rev 8:19-39
19. Gonyea W, Ericson GC, Bonde-Petersen F (1977) Skeletal muscle fiber splitting induced by weight-lifting exercise in cats. Acta Physiol Scand 99:105-109
20. Gullberg D, Tiger CF, Velling T (1999) Laminins during muscle development and in muscular dystrophies. Cell Mol Life Sci 56:442-460
21. Hall-Craggs EC (1970) The longitudinal division of fibres in overloaded rat skeletal muscle. J Anat 107:459-470
22. Hall-Craggs EC, Lawrence CA (1970) Longitudinal fibre division in skeletal muscle: a light- and electronmicroscopic study. Z Zellforsch Mikrosk Anat 109:481-494
23. Ho KW, Roy RR, Tweedle CD, Heusner WW, Van Huss WD, Carrow RE (1980) Skeletal muscle fiber splitting with weight-lifting exercise in rats. Am J Anat 157:433-440
24. James NT (1973) Compensatory hypertrophy in the extensor digitorum longus muscle of the rat. J Anat 116:57-65
25. Johnson LC, O'Shea JP (1969) Anabolic steroid: effects on strength development. Science 164:957-959
26. Kadi F (2000) Adaptation of human skeletal muscle to training and anabolic steroids. Acta Physiol Scand Suppl 646:1-52
27. Kadi F, Eriksson A, Holmner S, Butler-Browne GS, Thornell LE (1999a) Cellular adaptation of the trapezius muscle in strength-trained athletes. Histochem Cell Biol 111:189-195
28. Kadi F, Eriksson A, Holmner S, Thornell LE (1999b) Effects of anabolic steroids on the muscle cells of strength-trained athletes. Med Sci Sports Exerc 31:1528-1534
29. Kihira S, Nonaka I (1985) Congenital muscular dystrophy. A histochemical study with morphometric analysis on biopsied muscles. J Neurol Sci 70:139-149
30. Larsson L, Tesch PA (1986) Motor unit fibre density in extremely hypertrophied skeletal muscles in man. Electrophysiological signs of muscle fibre hyperplasia. Eur J Appl Physiol Occup Physiol 55:130-136
31. Richards RB, Passmore IK, Dempsey EF (1988) Skeletal muscle pathology in ovine congenital progressive muscular dystrophy 1 Histopathology and histochemistry. Acta Neuropathol (Berl) 77:161-167
32. Schmalbruch H (1976) The morphology of regeneration of skeletal muscles in the rat. Tissue Cell 8:673-692
33. Schmalbruch H (1985) Skeletal muscle. vol II 16. Springer, Berlin Heidelberg New York
34. Schwartz MS, Sargeant M, Swash M (1976) Longitudinal fibre splitting in neurogenic muscular disorders-its relation to the pathogenesis of "myopathic" change. Brain 99:617-636
35. Sternberger LA (1979) The unlabeled antibody (PAP) method, introduction. J Histochem Cytochem 27:1657
36. Swash M, Schwartz MS (1977) Implications of longitudinal muscle fibre splitting in neurogenic and myopathic disorders. J Neurol Neurosurg Psychiatry 40:1152-1159
37. Tesch PA (1988) Skeletal muscle adaptations consequent to long-term heavy resistance exercise. Med Sci Sports Exerc 20:S132-S134
38. Thornell LE, Edstrom L, Eriksson A, Henriksson KG, Angqvist KA (1980) The distribution of intermediate filament protein (skeletin) in normal and diseased human skeletal muscle - an immunohistochemical and electron-microscopic study. J Neurol Sci 47:153-170
39. Thornell LE, Johansson B, Eriksson A, Lehto VP, Virtanen I (1984) Intermediate filament and associated proteins in the human heart: an immunofluorescence study of normal and pathological hearts. Eur Heart J 5(Suppl F):231-241
40. Webster C, Silberstein L, Hays AP, Blau HM (1988) Fast muscle fibers are preferentially affected in Duchenne muscular dystrophy. Cell 52:503-513