Characterization of bulk properties of nanofibrous scaffolds from nanomechanical properties of single nanofibers

Journal of Biomedical Materials Research - Part A

Volumn 77, Issue 3, 2006, Pages 526-533

  Tan, E P S ^a   Lim, C T ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Atomic force microscopy; Elastic modulus; Mechanical tests; Nanofibrous scaffolds or foams; Polymer nanofiber

Indexed keywords

ATOMIC FORCE MICROSCOPY; ELASTIC MODULI; MECHANICAL TESTING; NANOMECHANICS; ORGANIC POLYMERS; SCAFFOLDS; TISSUE ENGINEERING;

NANOFIBROUS SCAFFOLDS; POLY(L-LACTIC ACID); POLYMER NANOFIBERS;

NANOFIBERS;

MOLECULAR SCAFFOLD; NANOFIBER; POLYLACTIC ACID;

ARTICLE; ATOMIC FORCE MICROSCOPY; FOAM; MECHANICAL STRESS; MOLECULAR MECHANICS; MOLECULAR MODEL; NANOENGINEERING; YOUNG MODULUS;

BIOCOMPATIBLE MATERIALS; LACTIC ACID; MATERIALS TESTING; MICROSCOPY, ATOMIC FORCE; MODELS, STRUCTURAL; NANOTECHNOLOGY; POLYMERS;

EID: 33748896156     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.30646     Document Type: Article

References (29)

1. Ingber DE. Mechanical and chemical determinants of tissue development. In: Lanza RP, Langer R, Vacanti J, editors. Principles of Tissue Engineering, 2nd ed, San Diego, CA: Academic Press; 2000. p 101-110.
2. Thomson RC, Shung AK, Yaszemski MJ, Mikos AG. Polymer scaffold processing. In: Lanza RP, Langer R, Vacanti J, editors. Principles of Tissue Engineering, 2nd ed, San Diego, CA: Academic Press; 2000. p 251-262.
3. Ma PX, Langer R. Fabrication of biodegradable polymer foams for cell transplantation and tissue engineering. In: Morgan JR, Yarmush ML, editors. Tissue Engineering Methods and Protocols, Vol. 18. New Jersey: Humana; 1999. p 47-56.
4. Opas M. Expression of the Differentiated phenotype by epithelial-cells in vitro is regulated by both biochemistry and mechanics of the substratum. Dev Biol 1989;131:281-293.
5. Vernon RB, Angello JC, Iruelaarispe ML, Lane TF, Sage EH. Reorganization of basement-membrane matrices by cellular traction promotes the formation of cellular networks in vitro. Lab Invest 1992;66:536-547.
6. Choquet D, Felsenfeld DP, Sheetz MP. Extracellular matrix rigidity causes strengthening of integrin-cytoskeleton linkages. Cell 1997;88:39-48.
7. Mitchison TJ, Cramer LP. Actin-based cell motility and cell locomotion. Cell 1996;84:371-379.
8. Balgude AP, Yu X, Szymanski A, Bellamkonda RV. Agarose gel stiffness determines rate of DRG neurite extension in 3D cultures. Biomaterials 2001;22:1077-1084.
9. Chiquet M, Matthisson M, Koch M, Tannheimer M, ChiquetEhrismann R. Regulation of extracellular matrix synthesis by mechanical stress. Biochem Cell Biol 1996;74:737-744.
10. Ma PX, Zhang R. Synthetic nano-scale fibrous extracellular matrix. J Biomed Mater Res 1999;46:60-72.
11. Tan EPS, Lim CT. Physical properties of a single polymeric nanofiber. Appl Phys Lett 2004;84:1603-1605.
12. Tan EPS, Lim CT. A novel approach to tensile testing of micro-and nanoscale fibers. Rev Sci Instrum 2004;75:2581-2585.
13. Tan EPS, Ng SY, Lim CT. Tensile testing of a single ultrafine polymeric fiber. Biomaterials 2005;26:1453-1456.
14. Roberts AP, Garboczi EJ. Elastic properties of model random three-dimensional open-cell solids. J Mech Phys Solids 2002; 50:33-55.
15. Zhu HX, Hobdell JR, Windle AH. Effects of cell irregularity on the elastic properties of open-cell foams. Acta Mater 2000;48: 4893-4900.
16. Gibson LJ, Ashby MF. The Mechanics of Foams: Basic Results. In: Cellular Solids: Structure and Properties, 2nd ed. Cambridge: Cambridge University Press; 1997. p 175-234. Cambridge Solid State Science Series.
17. Guo XE, Gibson LJ. Behavior of intact and damaged honeycombs: A finite element study. Int J Mech Sci 1999;41:85-105.
18. Gibson LJ, Ashby MF. Cancellous bone. In: Cellular Solids: Structure and Properties, 2nd ed. Cambridge: Cambridge University Press; 1997. p 429-452. Cambridge Solid State Science Series.
19. Satcher RL, Dewey CF. Theoretical estimates of mechanical properties of the endothelial cell cytoskeleton. Biophys J 1996; 71:109-118.
20. Zhu HX, Knott JF, Mills NJ. Analysis of the elastic properties of open-cell foams with tetrakaihecahedral cells. J Mech Phys Solids 1997;45:319-343.
21. Williams RE. Space-filling polyhedron: its relation to aggregates of soap bubbles, plant cells and metal crystallites. Science 1968;161:276-277.
22. Gibson LJ, Ashby MF. The structure of cellular solids. In: Cellular Solids: Structure and Properties, 2nd ed. Cambridge: Cambridge University Press; 1997. p 15-51. Cambridge Solid State Science Series.
23. Garlotta D. A literature review of poly(lactic acid). J Polym Environ 2001;9:63-84.
24. Yuan X, Mak AFT, Kwok KW, Yung BKO, Yao K. Characterization of poly(L-lactic acid) fibers produces by melt spinning. J Appl Polym Sci 2001;81:251-260.
25. Zheng J, Lamoureux P, Santiago V, Dennerll T, Buxbaum RE, Heidemann SR. Tensile Regulation of Axonal Elongation and Initiation. J Neurosci 1991;11:1117-1125.
26. Heidemann SR, Buxbaum RE. Mechanical tension as a regulator of axonal development. Neurotoxicology 1994;15:95-107.
27. Chada S, Lamoureux P, Buxbaum RE, Heidemann SR. Cytomechanics of neurite outgrowth from chick brain neurons. J Cell Sci 1997;110:1179-1186.
28. Zhang Y, Zhang MQ Microstructural and mechanical characterization of chitosan scaffolds reinforced by calcium phosphates. J Non-Cryst Solids , 2001;282:159-164.
29. Gibson LJ, Ashby MF. The mechanics of honeycombs. Cellular Solids: Structure and Properties, 2nd ed. Cambridge Solid State Science Series. Cambridge: Cambridge University Press; 1997. p 93-174.