Methodological issues in the investigation of ginseng as an intervention for fatigue

Clinical Nurse Specialist

Volumn 20, Issue 4, 2006, Pages 183-189

  Elam, Julie L ^a   Carpenter, Janet S ^a   Shu, Xiao Ou ^b   Boyapati, Sonia ^b   Friedmann Gilchrist, Janet ^c  

^a INDIANA UNIVERSITY   (United States)

^b VANDERBILT INGRAM CANCER CENTER   (United States)

^c U S DEPARTMENT OF AGRICULTURE   (United States)

Author keywords

Breast cancer; Complementary therapy; Fatigue; Pilot study

Indexed keywords

PLANT MEDICINAL PRODUCT;

ARTICLE; BREAST TUMOR; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; DRUG ADMINISTRATION; DRUG CONTRAINDICATION; DRUG EFFECT; DRUG MONITORING; EQUIPMENT; FATIGUE; FEASIBILITY STUDY; FEMALE; GINSENG; HEALTH SERVICE; HUMAN; IMMUNOLOGY; INSTRUMENTATION; METHODOLOGY; MIDDLE AGED; NATURAL KILLER CELL; PATIENT SELECTION; PHYTOTHERAPY; PILOT STUDY; RANDOMIZED CONTROLLED TRIAL; SLEEP DISORDER; TREATMENT OUTCOME; UNITED STATES;

BREAST NEOPLASMS; CROSS-OVER STUDIES; DOUBLE-BLIND METHOD; DRUG ADMINISTRATION SCHEDULE; DRUG MONITORING; EQUIPMENT FAILURE; FATIGUE; FEASIBILITY STUDIES; FEMALE; HEALTH SERVICES NEEDS AND DEMAND; HUMANS; KILLER CELLS, NATURAL; MIDDLE AGED; PANAX; PATIENT SELECTION; PHYTOTHERAPY; PILOT PROJECTS; PLANT PREPARATIONS; RESEARCH DESIGN; SLEEP DISORDERS; SOUTHEASTERN UNITED STATES; TREATMENT OUTCOME;

EID: 33748870448     PISSN: 08876274     EISSN: 15389782     Source Type: Journal    
DOI: 10.1097/00002800-200607000-00007     Document Type: Article

References (46)

1. Jemal A, Murray T, Ward E, et al. Cancer statistics, 2005. CA Cancer J Clin. 2005;55:10-30.
2. American Cancer Society. Cancer Facts & Figures 2005. Rep. 5006.05. Atlanta: American Cancer Society; 2004.
3. U.S. Bureau of the Census. Population Projections of the United States by Age, Sex, Race, and Hispanic Origin: 1995-2050. Rep. P25-1130. Washington, DC: U.S. Department of Commerce; 1996.
4. Piper BF, Lindsey AM, Dodd MJ. Fatigue mechanisms in cancer patients: developing nursing theory. Oncol Nurs Forum. 1987;14:17-23.
5. Corless IB, Bunch EH, Kemppainen JK, et al. Self-care for fatigue in patients with HIV. Oncol Nurs Forum. 2002;29:E60-E69.
6. Berger AM, Walker SN. An explanatory model of fatigue in women receiving adjuvant breast cancer chemotherapy. Nurs Res. 2001;50:42-52.
7. Berger AM, Higginbotham P. Correlates of fatigue during and following adjuvant breast cancer chemotherapy: a pilot study. Oncol Nurs Forum. 2000;27:1443-1448.
8. Berger AM. Treating fatigue in cancer patients. Oncologist. 2003;8:10-14.
9. Berger AM. Patterns of fatigue and activity and rest during adjuvant breast cancer chemotherapy. Oncol Nurs Forum. 1998;25:51-62.
10. Karch SB. Consumer's Guide to Herbal Medicine. New York: Advanced Research Press; 1999.
11. Eisenberg DM, Davis RB, Ettner SL, et al. Trends in alternative medicine use in the United States, 1990-1997: results of a follow-up national survey. JAMA. 1998;280:1569-1575.
12. Cui Y, Shu XO, Gao Y, et al. Use of complementary and alternative medicine by Chinese women with breast cancer. Breast Cancer Res Treat. 2004;85:263-270.
13. Cui Y, Shu XO, Gao YT, Cai H, Tao MH, Zheng W. Association of ginseng use with survival and quality of life among breast cancer patients. Am J Epidemiol. 2006;163(7):645-653.
14. Block KI, Mead MN. Immune system effects of echinacea, ginseng, and astragalus: a review. Integr Cancer Ther. 2003;2:247-267.
15. Scaglione F, Ferrara F, Dugnani S, Falchi M, Santoro G, Fraschini F. Immunomodulatory effects of two extracts of Panax ginseng C.A. Meyer. Drugs Exp Clin Res. 1990;16:537-542.
16. See DM, Broumand N, Sahl L, Tilles JG. In vitro effects of echinacea and ginseng on natural killer and antibody-dependent cell cytotoxicity in healthy subjects and chronic fatigue syndrome or acquired immunodeficiency syndrome patients. Immunopharmacology. 1997;35:229-235.
17. Attele AS, Wu JA, Yuan CS. Ginseng pharmacology: multiple constituents and multiple actions. Biochem Pharmacol. 1999;58:1685-1693.
18. Bahrke MS, Morgan WR. Evaluation of the ergogenic properties of ginseng: an update. Sports Med. 2000;29:113-133.
19. Miller LG. Herbal medicinals: selected clinical considerations focusing on known or potential drug-herb interactions. Arch Intern Med. 1998;158:2200-2211.
20. Sato T, Miyata G. The nutraceutical benefit, Part II: Ginseng. Nutrition. 2000;16:391-392.
21. Shin HR, Kim JY, Yun TK, Morgan G, Vainio H. The cancer-preventive potential of Panax ginseng: a review of human and experimental evidence. Cancer Causes Control. 2000;11:565-576.
22. Bentler SE, Hartz AJ, Kuhn EM. Prospective observational study of treatments for unexplained chronic fatigue. J Clin Psychiatry. 2005;66:625-632.
23. Cardinal BJ, Engels HJ. Ginseng does not enhance psychological well-being in healthy, young adults: results of a double-blind, placebo-controlled, randomized clinical trial. J Am Diet Assoc. 2001;101:655-660.
24. Hu Z, Yang X, Ho PC, et al. Herb-drug interactions: a literature review. Drugs. 2005;65:1239-1282.
25. Medical Economics Company. PDR for Herbal Medicines. Montvale, NJ: Medical Economics Company; 1998.
26. Coon JT, Ernst E. Panax ginseng: a systematic review of adverse effects and drug interactions. Drug Saf. 2002;25:323-344.
27. Foster S, Tyler VE. Tyler's Honest Herbal: A Sensible Guide to the Use of Herbs and Related Remedies. New York: Haworth Herbal Press; 1999.
28. Baker F, Denniston M, Zabora J, Polland A, Dudley WN. A POMS short form for cancer patients: psychometric and structural evaluation. Psychooncology. 2002;11:273-281.
29. Curran SI, Andrykowski M, Studts JM. Short form of the Profile of Mood States (POMS-SF): psychometric information. Psychol Assess. 1995;7:80-83.
30. McNair PM, Lorr M, Droppelman L. POMS Manual, 2nd ed. San Diego: Educational and Testing Service; 1981.
31. Shacham S. A shortened version of the Profile of Mood States. J Pers Assess. 1983;47:305-306.
32. Blesch KS, Paice JA, Wickham R, et al. Correlates of fatigue in people with breast or lung cancer. Oncol Nurs Forum. 1991;18:81-87.
33. Baker A, Simpson S, Dawson D. Sleep disruption and mood changes associated with menopause. J Psychosom Res. 1997;43:359-369.
34. Carpenter JS, Andrykowski MA, Cordova M, et al. Hot flashes in postmenopausal women treated for breast carcinoma: prevalence, severity, correlates, management, and relation to quality of life. Cancer. 1998;82:1682-1691.
35. Ancoli-Israel S, Cole R, Alessi C, Chambers M, Moorcroft W, Pollak CP. The role of actigraphy in the study of sleep and circadian rhythms. Sleep. 2003;26:342-392.
36. Ancoli-Israel S, Liu L, Marler MR, et al. Fatigue, sleep, and circadian rhythms prior to chemotherapy for breast cancer. Support Care Cancer. 2005;14(3):201-209.
37. Jean-Louis G, von Gizycki H, Zizi F, Spielman A, Hauri P, Taub H. The actigraph data analysis software: II. A novel approach to scoring and interpreting sleep-wake activity. Percept Mot Skills. 1997;85:219-226.
38. Moe KE. Hot flashes and sleep in women. Sleep Med Rev. 2004;8:487-497.
39. Mathie MJ, Coster AC, Lovell NH, Celler BG. Accelerometry: providing an integrated, practical method for long-term, ambulatory monitoring of human movement. Physiol Meas. 2004;25:R1-R20.
40. Mathie MJ, Coster AC, Lovell NH, Celler BG. Detection of daily physical activities using a triaxial accelerometer. Med Biol Eng Comput. 2003;41:296-301.
41. Kim JY, Germolec DR, Luster MI. Panax ginseng as a potential immunomodulator: studies in mice. Immunopharmacol Immunotoxicol. 1990;12:257-276.
42. Ellis SJ, Adams RF. The cult of the double-blind placebo-controlled trial. Br J Clin Pract. 1997;51:36-39.
43. Vickers A. Methodological issues in complementary and alternative medicine research: a personal reflection on 10 years of debate in the United Kingdom. J Altern Complement Med. 1996;2:515-524.
44. Johnson MO, Remien RH. Adherence to research protocols in a clinical context: challenges and recommendations from behavioral intervention trials. Am J Psychother. 2003;57:348-360.
45. Wiklund IK, Mattsson LA, Lindgren R, Limoni C. Effects of a standardized ginseng extract on quality of life and physiological parameters in symptomatic postmenopausal women: a double-blind, placebo-controlled trial. Swedish Alternative Medicine Group. Int J Clin Pharmacol Res. 1999;19:89-99.
46. North American Menopause Society. Treatment of menopause-associated vasomotor symptoms: position statement of The North American Menopause Society. Menopause. 2004:11-33.