메뉴 건너뛰기




Volumn 2, Issue 4, 2005, Pages 334-339

Microwave and classical activation of solvent-free reactions of N-isopropyl arylidene amines with alkyl cyanoacetates

Author keywords

Cyclohexenes; Electrophilie alkenes; Non thermal microwave effect; Physical organic chemistry; Solvent free reactions

Indexed keywords


EID: 33748869922     PISSN: 15701786     EISSN: None     Source Type: Journal    
DOI: 10.2174/1570178054038786     Document Type: Review
Times cited : (4)

References (30)
  • 10
    • 0011932271 scopus 로고    scopus 로고
    • Loupy, A. Ed, Wiley-VCH Verlag GmbH& Co. KGaA: Weinheim
    • Loupy, A. Ed, Microwaves in Organic Synthesis, Wiley-VCH Verlag GmbH& Co. KGaA: Weinheim, 2002.
    • (2002) Microwaves in Organic Synthesis
  • 14
    • 46149087667 scopus 로고    scopus 로고
    • Typical experimental procedure for synthesis of 6ab and 4ab A neat mixture of N-isopropytbenzylidene amine la (10 mmol, and ethyl cyanoacetate 2b (30 mmol, was allowed to stand at room temperature during 8 days. Addition of EtOH 95% has for consequence the crystallization of cyclohexene 6ab (56% yield of isolated pure product, Mp: 216°C. 1H -NMR (500 MHz, CDC13) δH, 0.68 (t, 3H, J 7.1, 1.06 (t, 3H, J 7.1, 3.73 (qm, 2H, J 7.1, 4.00 (d, HA, J 12.1, 4.07 (qm, 2H, J 7.1, 4.18 (dd, H B, J 12.1, J 2.3, 4.49 (d, HC, J 2.3, 5.04 (s, 2H, NH2, 7.25-7.48 (m, 10H arom, δC (125 MHz, CDC13) 13.29 and 13.35 (qm, CO2CH2CH3, J 127.6, 47.90 (dm, C3-HA, J 132.0, 48.34 (dm, C6-HC, J 138, 49.23 (dm, C2-HB, J 138, 57.86 t, C
    • 3) 1.42 (t, 3H, J 7.1), 4.41 (q, 2H, J 7.1), 7.30-8.03 (5 H arom), 8.27 (s, 1H).
  • 15
    • 46149096645 scopus 로고    scopus 로고
    • Crystal data for 6ab: C26H25 N3O4, Mr= 443.49, monoclinic, P21/c, a= 7.642(4, b, 19.999(6, c, 15.643(5) Å, b, 93.71(4)°, V, 2386(, Å-3, Z, 4, Dx, 1.235 Mg.m-3, λ(MoKα, 0.71073Å, μ, 0.84 cm-1, F(000, 936, T, 293 K. Sample (0.45*0.38*0.33 mm) studied on CAD4 NONIUS (MoKα, Range HKL, H 0,9 K 0,25 L -19,19, 5580 unique reflections (3027 with 1>2.0σ(I, Structure solved with SIR-97 (Altomare & al, 1998) and refined with SHELXL97 (Sheldrick, 1997) by the full-matrix least-square techniques (use of F square magnitude; x, y, z, βij for C, 0Oand N atoms, x, y, z in riding mode for H atoms; 299 variables and 3027 observations with 1>2.0δ(I, calc w=1/[(σ2(Fo)2+(0.0596p)2+0.2596P] where p=(Fo2+2Fc2)/3 with the resulting R, 0.045, RW, 0.109 and S
    • W= 1.013(residual Ap ≤ 0. 18 e.Å-3) Crystallographic date: have been deposited at the Cambridge Crystallographic Data Centre under the number CCDC 220602 and may be obtained free of charge from the Director(depositγcdc. cam. ac.uk).
  • 17
    • 46149127479 scopus 로고    scopus 로고
    • International Tables for X-ray Crystallography, C. Ed AJ.C. (Kluwer Academic Publishers, Dordrecht.), 1992.
    • International Tables for X-ray Crystallography, Vol.C. Ed AJ.C. (Kluwer Academic Publishers, Dordrecht.), 1992.
  • 19
    • 46149122647 scopus 로고    scopus 로고
    • Sheldrick, G.M. SHELX97. Program for the Refinement of Crystal Structures, 1997, Univ. of Göttingen, Germany.
    • Sheldrick, G.M. SHELX97. Program for the Refinement of Crystal Structures, 1997, Univ. of Göttingen, Germany.
  • 22
    • 46149108716 scopus 로고    scopus 로고
    • Prolabo, Fr. Pat. 62241/D, 14669 FR, December 23th 1991.
    • Prolabo, Fr. Pat. 62241/D, 14669 FR, December 23th 1991.
  • 23
    • 84879823935 scopus 로고
    • Rhône-Poulenc/Prolabo
    • Patent number 84/03496, October 27th
    • Commarmot, R.; Didenot, R.; Gardais, J.F. Rhône-Poulenc/Prolabo Patent number 84/03496 - October 27th 1986.
    • (1986)
    • Commarmot, R.1    Didenot, R.2    Gardais, J.F.3
  • 24
    • 46149112906 scopus 로고    scopus 로고
    • J Lazzareschi, G. Gazz. Chim. Ital. 1937, 67, 371.
    • J Lazzareschi, G. Gazz. Chim. Ital. 1937, 67, 371.
  • 28
    • 46149110211 scopus 로고
    • Ph.D.thesis, Université de Rennes 1, no 1206
    • Abdallah-El Ayoubi, S. Ph.D.thesis, Université de Rennes 1, no 1206, 1994.
    • (1994)
    • Abdallah-El Ayoubi, S.1
  • 30
    • 46149096366 scopus 로고    scopus 로고
    • EC contract G5RD-CT 2001 00546: coordinator Prof J.Lucas, University of Liverpool, UK.
    • EC contract G5RD-CT 2001 00546: coordinator Prof J.Lucas, University of Liverpool, UK.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.