Topical cidofovir for treatment of resistant viral infections

International Journal of Pharmaceutical Compounding

Volumn 10, Issue 5, 2006, Pages 324-328

  McElhiney, Linda F ^a  

^a INDIANA UNIVERSITY HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACICLOVIR; ALPHA INTERFERON; CIDOFOVIR; DERMOVAN; DNA POLYMERASE; FOSCARNET; GANCICLOVIR; IMIQUIMOD; LANOLIN ALCOHOL; PLACEBO; PODOPHYLLOTOXIN; PROPYLENE GLYCOL; RETINOIC ACID; THYMIDINE KINASE; TRICHLOROACETIC ACID;

BIRTH DEFECT; CANCER; CAUTERIZATION; CLINICAL TRIAL; CONDYLOMA; CONDYLOMA ACUMINATUM; DRUG COST; DRUG EFFICACY; DRUG EXCRETION; DRUG FORMULATION; DRUG HALF LIFE; DRUG MECHANISM; DRUG METABOLISM; DRUG PROTEIN BINDING; DRUG TOLERABILITY; GINGIVITIS; HERPES VIRUS INFECTION; HUMAN; LASER COAGULATION; MOLLUSCUM CONTAGIOSUM; MUCOSAL EROSION; NEPHROTOXICITY; NEUTROPENIA; NONHUMAN; OLIGOSPERMIA; PATIENT MONITORING; RETINITIS; REVIEW; SIDE EFFECT; SKIN DEFECT; SKIN REDNESS; TREATMENT OUTCOME; VERRUCA VULGARIS; VIRUS INFECTION;

EID: 33748795091     PISSN: 10924221     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (10)

1. Mendel DB, Barkhimer DB, Chen MS. Biochemical basis for increased susceptibility to cidofovir of herpes simplex viruses with altered or deficient thymidine kinase activity. Antimicrob Agents Chemother 1995; 39(9): 2120-2122.
2. Morphin F, Snoeck R, Andrei G et al. Phenotypic resistance of herpes simplex virus 1 strains selected in vitro with antiviral compounds and combinations thereof. Antivir Chem Chemother 1996; 7: 270-275.
3. Vistide (cidofovir injection) [package insert]. Louisville, KY: Cardinal Health; 2000.
4. Calista D. Resolution of recalcitrant human papillomavirus gingival infection with topical cidofovir. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2000; 90(6): 713-715.
5. Matteelli A, Beltrame A, Graifemberghi S et al. Efficacy and tolerability of topical 1% cidofovir cream for the treatment of external anogenital warts in HIV-infected persons. Sex Transm Dis 2001; 28(6): 343-346.
6. Orlando G, Fasolo MM, Beretta R et al. Combined surgery and cidofovir is an effective treatment for genital warts in HIV-infected patients. AIDS 2002; 16(3): 447-450.
7. Davies EG, Thrasher A, Lacey K et al. Topical cidofovir for severe molluscum contagiosum. Lancet 1999; 353(9169): 2042.
8. Meadows KP, Tyring SK, Pavia AT et al. Resolution of recalcitrant molluscum contagiosum virus lesions in human immunodeficiency virus-infected patients treated with cidofovir. Arch Dermatol 1997; 133(8): 987-990.
9. Toro JR, Wood LV, Patel NK et al. Topical cidofovir: A novel treatment for recalcitrant molluscum contagiosum in children infected with human immunodeficienty virus 1. Arch Dermatol 2000; 136(8): 983-985.
10. Zabawski EJ Jr, Cockerell CJ. Topical and intralesional cidofovir: A review of pharmacology and therapeutic effects. J Am Acad Dermatol 1998; 39(5 Pt 1): 741-745.