A novel antiproliferative agent, phenylpyridineylbutenol, isolated from Streptomyces sp.

Bioorganic and Medicinal Chemistry Letters

Volumn 16, Issue 21, 2006, Pages 5643-5645

  Shin, Choonshik ^a   Lim, Haeyoung ^b   Moon, Sangik ^a   Kim, Seunghyun ^a   Yong, Yeonjoong ^a   Kim, Bum Joon ^c   Lee, Chul Hoon ^b   Lim, Yoongho ^a  

^a Konkuk University   (South Korea)

^b Hanyang University   (South Korea)

^c Seoul National University   (South Korea)

Author keywords

Antiproliferative; Phenylpyridineylbutenol; Streptomyces sp.

Indexed keywords

4 PHENYL 3 (PYRIDINE 2 YL)BUT 2 EN 1 OL; ANTINEOPLASTIC AGENT; PYRIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIMICROBIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG CONFORMATION; DRUG DETERMINATION; DRUG ISOLATION; DRUG STRUCTURE; FEMALE; HUMAN; HUMAN CELL; MOLECULAR MODEL; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEAR OVERHAUSER EFFECT; STREPTOMYCES;

ANTINEOPLASTIC AGENTS; BUTANOLS; CELL PROLIFERATION; HELA CELLS; HUMANS; PYRIDINES; STREPTOMYCES;

STREPTOMYCES SP.;

EID: 33748788589     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.08.015     Document Type: Article

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7. 6) δ 35.2 (t, C-9), 60.3 (t, C-1), 123.1 (d, C-5), 123.7 (d, C-7), 127.2 (d, C-4′), 129.6 (d, C-2′/6′), 129.6 (d, C-3′/5′), 133.9 (d,C-2), 138.6 (d, C-6), 140.5 (s, C-1′), 140.7 (s, C-3), 149.7 (d, C-8), 160.3 (s, C-4).
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