Conformational re-analysis of (+)-meptazinol: An opioid with mixed analgesic pharmacophores

Acta Pharmacologica Sinica

Volumn 27, Issue 9, 2006, Pages 1247-1252

  Li, Wei ^a   Wang, Xing Hai ^a   Lau, Choi Wan ^a   Tang, Yun ^a,b   Xie, Qiong ^a   Qiu, Zhui Bai ^a  

^a FUDAN UNIVERSITY   (China)

^b EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

(+)meptazinol; Arylpiperi dines; Conformational Analysis; Opioid analgesics; Pharmacophore

Indexed keywords

3 O METHYLETORPHINE; 6 HYDROXYLEVALORPHAN; ANALGESIC AGENT; AZIDOMORPHINE; BENZOFURO[2,3 C]PYRIDIN 6 OL; CODEINE; CYCLASOZINE; MEPTAZINOL; MORPHINE; N ALLYLNORMETAZOCINE; NALBUPHINE; NALOXONE; OPIATE; PETHIDINE; PIPERIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANALYSIS; ARTICLE; DRUG CONFORMATION; DRUG POTENCY; DRUG SOLUTION; DRUG STRUCTURE; MATHEMATICAL MODEL; MOLECULAR MODEL; NUCLEAR MAGNETIC RESONANCE; PHARMACOPHORE; STRUCTURE ACTIVITY RELATION; VALIDATION PROCESS;

ANALGESICS, OPIOID; MEPTAZINOL; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33748780928     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1111/j.1745-7254.2006.00375.x     Document Type: Article

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