Genetic interactions between Drosophila melanogaster menin and Jun/Fos

Developmental Biology

Volumn 298, Issue 1, 2006, Pages 59-70

  Cerrato, Aniello ^a   Parisi, Michael ^a   Anna, Sonia Santa ^b   Missirlis, Fanis ^c   Guru, Siradanahalli ^b   Agarwal, Sunita ^a   Sturgill, David ^a   Talbot, Thomas ^d   Spiegel, Allen ^a   Collins, Francis ^b   Chandrasekharappa, Settara ^b   Marx, Stephen ^a   Oliver, Brian ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^c EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^d NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

AP1; Cleft thorax; Life span; Multiple endocrine neoplasia type I; Oxidative stress; Paraquat; Tumor suppressor

Indexed keywords

METHIONINE; PROTEIN FOS;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; EMBRYO; FEMALE; FERTILIZATION; GENE INTERACTION; HOMOZYGOSITY; MALE; NONHUMAN; NULL ALLELE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION;

DROSOPHILA MELANOGASTER; MAMMALIA;

EID: 33748770100     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ydbio.2006.06.013     Document Type: Article

References (36)

1. Agarwal S.K., Guru S.C., Heppner C., Erdos M.R., Collins R.M., Park S.Y., Saggar S., Chandrasekharappa S.C., Collins F.S., Spiegel A.M., Marx S.J., and Burns A.L. Menin interacts with the AP1 transcription factor JunD and represses JunD-activated transcription. Cell 96 (1999) 143-152
2. Agarwal S.K., Novotny E.A., Crabtree J.S., Weitzman J.B., Yaniv M., Burns A.L., Chandrasekharappa S.C., Collins F.S., Spiegel A.M., and Marx S.J. Transcription factor JunD, deprived of menin, switches from growth suppressor to growth promoter. Proc. Natl. Acad. Sci. U. S. A. 100 (2003) 10770-10775
3. Agarwal S.K., Lee Burns A., Sukhodolets K.E., Kennedy P.A., Obungu V.H., Hickman A.B., Mullendore M.E., Whitten I., Skarulis M.C., Simonds W.F., Mateo C., Crabtree J.S., Scacheri P.C., Ji Y., Novotny E.A., Garrett-Beal L., Ward J.M., Libutti S.K., Richard Alexander H., Cerrato A., Parisi M.J., Santa Anna A.S., Oliver B., Chandrasekharappa S.C., Collins F.S., Spiegel A.M., and Marx S.J. Molecular pathology of the MEN1 gene. Ann. N. Y. Acad. Sci. 1014 (2004) 189-198
4. Agnes F., Suzanne M., and Noselli S. The Drosophila JNK pathway controls the morphogenesis of imaginal discs during metamorphosis. Development 126 (1999) 5453-5462
5. Benson D.A., Karsch-Mizrachi I., Lipman D.J., Ostell J., and Wheeler D.L. GenBank. Nucleic Acids Res. 33 (2005) D34-D38
6. Brand A.H., and Perrimon N. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118 (1993) 401-415
7. Busygina V., Suphapeetiporn K., Marek L.R., Stowers R.S., Xu T., and Bale A.E. Hypermutability in a Drosophila model for multiple endocrine neoplasia type 1. Hum. Mol. Genet. 13 (2004) 2399-2408
8. Calleja M., Moreno E., Pelaz S., and Morata G. Visualization of gene expression in living adult Drosophila. Science 274 (1996) 252-255
9. Chandrasekharappa S.C., Guru S.C., Manickam P., Olufemi S.E., Collins F.S., Emmert-Buck M.R., Debelenko L.V., Zhuang Z., Lubensky I.A., Liotta L.A., Crabtree J.S., Wang Y., Roe B.A., Weisemann J., Boguski M.S., Agarwal S.K., Kester M.B., Kim Y.S., Heppner C., Dong Q., Spiegel A.M., Burns A.L., and Marx S.J. Positional cloning of the gene for multiple endocrine neoplasia-type 1. Science 276 (1997) 404-407
10. Crabtree J.S., Scacheri P.C., Ward J.M., Garrett-Beal L., Emmert-Buck M.R., Edgemon K.A., Lorang D., Libutti S.K., Chandrasekharappa S.C., Marx S.J., Spiegel A.M., and Collins F.S. A mouse model of multiple endocrine neoplasia, type 1, develops multiple endocrine tumors. Proc. Natl. Acad. Sci. U. S. A. 98 (2001) 1118-1123
11. Crabtree J.S., Scacheri P.C., Ward J.M., McNally S.R., Swain G.P., Montagna C., Hager J.H., Hanahan D., Edlund H., Magnuson M.A., Garrett-Beal L., Burns A.L., Ried T., Chandrasekharappa S.C., Marx S.J., Spiegel A.M., and Collins F.S. Of mice and MEN1: insulinomas in a conditional mouse knockout. Mol. Cell. Biol. 23 (2003) 6075-6085
12. Duffy J.B. GAL4 system in Drosophila: a fly geneticist's Swiss army knife. Genesis 34 (2002) 1-15
13. FlyBase. The FlyBase database of the Drosophila genome projects and community literature. Nucleic Acids Res. 31 (2003) 172-175
14. Gallo A., Cuozzo C., Esposito I., Maggiolini M., Bonofiglio D., Vivacqua A., Garramone M., Weiss C., Bohmann D., and Musti A.M. Menin uncouples Elk-1, JunD and c-Jun phosphorylation from MAP kinase activation. Oncogene 21 (2002) 6434-6445
15. Gentleman R.C., Carey V.J., Bates D.M., Bolstad B., Dettling M., Dudoit S., Ellis B., Gautier L., Ge Y., Gentry J., Hornik K., Hothorn T., Huber W., Iacus S., Irizarry R., Leisch F., Li C., Maechler M., Rossini A.J., Sawitzki G., Smith C., Smyth G., Tierney L., Yang J.Y., and Zhang J. Bioconductor: open software development for computational biology and bioinformatics. Genome Biol. 5 (2004) R80
16. Gobl A.E., Berg M., Lopez-Egido J.R., Oberg K., Skogseid B., and Westin G. Menin represses JunD-activated transcription by a histone deacetylase-dependent mechanism. Biochim. Biophys. Acta 1447 (1999) 51-56
17. Goldsmith P., Gierschik P., Milligan G., Unson C.G., Vinitsky R., Malech H.L., and Spiegel A.M. Antibodies directed against synthetic peptides distinguish between GTP-binding proteins in neutrophil and brain. J. Biol. Chem. 262 (1987) 14683-14688
18. Guru S.C., Goldsmith P.K., Burns A.L., Marx S.J., Spiegel A.M., Collins F.S., and Chandrasekharappa S.C. Menin, the product of the MEN1 gene, is a nuclear protein. Proc. Natl. Acad. Sci. U. S. A. 95 (1998) 1630-1634
19. Guru S.C., Prasad N.B., Shin E.J., Hemavathy K., Lu J., Ip Y.T., Agarwal S.K., Marx S.J., Spiegel A.M., Collins F.S., Oliver B., and Chandrasekharappa S.C. Characterization of a MEN1 ortholog from Drosophila melanogaster. Gene 263 (2001) 31-38
20. Huet F., Lu J.T., Myrick K.V., Baugh L.R., Crosby M.A., and Gelbart W.M. A deletion-generator compound element allows deletion saturation analysis for genomewide phenotypic annotation. Proc. Natl. Acad. Sci. U. S. A. 99 (2002) 9948-9953
21. Hughes C.M., Rozenblatt-Rosen O., Milne T.A., Copeland T.D., Levine S.S., Lee J.C., Hayes D.N., Shanmugam K.S., Bhattacharjee A., Biondi C.A., Kay G.F., Hayward N.K., Hess J.L., and Meyerson M. Menin associates with a trithorax family histone methyltransferase complex and with the hoxc8 locus. Mol. Cell 13 (2004) 587-597
22. Karnik S.K., Hughes C.M., Gu X., Rozenblatt-Rosen O., McLean G.W., Xiong Y., Meyerson M., and Kim S.K. Menin regulates pancreatic islet growth by promoting histone methylation and expression of genes encoding p27Kip1 and p18INK4c. Proc. Natl. Acad. Sci. U. S. A. 102 (2005) 14659-14664
23. Kim H., Lee J.E., Kim B.Y., Cho E.J., Kim S.T., and Youn H.D. Menin represses JunD transcriptional activity in protein kinase Ctheta-mediated Nur77 expression. Exp. Mol. Med. 37 (2005) 466-475
24. Knapp J.I., Heppner C., Hickman A.B., Burns A.L., Chandrasekharappa S.C., Collins F.S., Marx S.J., Spiegel A.M., and Agarwal S.K. Identification and characterization of JunD missense mutants that lack menin binding. Oncogene 19 (2000) 4706-4712
25. Kockel L., Homsy J.G., and Bohmann D. Drosophila AP-1: lessons from an invertebrate. Oncogene 20 (2001) 2347-2364
26. Martin-Blanco E., Pastor-Pareja J.C., and Garcia-Bellido A. JNK and decapentaplegic signaling control adhesiveness and cytoskeleton dynamics during thorax closure in Drosophila. Proc. Natl. Acad. Sci. U. S. A. 97 (2000) 7888-7893
27. Maruyama K., Tsukada T., Honda M., Nara-Ashizawa N., Noguchi K., Cheng J., Ohkura N., Sasaki K., and Yamaguchi K. Complementary DNA structure and genomic organization of Drosophila menin. Mol. Cell. Endocrinol. 168 (2000) 135-140
28. Mechta-Grigoriou F., Gerald D., and Yaniv M. The mammalian Jun proteins: redundancy and specificity. Oncogene 20 (2001) 2378-2389
29. Milne T.A., Hughes C.M., Lloyd R., Yang Z., Rozenblatt-Rosen O., Dou Y., Schnepp R.W., Krankel C., Livolsi V.A., Gibbs D., Hua X., Roeder R.G., Meyerson M., and Hess J.L. Menin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitors. Proc. Natl. Acad. Sci. U. S. A. 102 (2005) 749-754
30. Naito J., Kaji H., Sowa H., Hendy G.N., Sugimoto T., and Chihara K. Menin suppresses osteoblast differentiation by antagonizing the AP-1 factor, JunD. J. Biol. Chem. 280 (2005) 4785-4791
31. Papaconstantinou M., Wu Y., Pretorius H.N., Singh N., Gianfelice G., Tanguay R.M., Campos A.R., and Bedard P.A. Menin is a regulator of the stress response in Drosophila melanogaster. Mol. Cell. Biol. 25 (2005) 9960-9972
32. Rubin G.M., and Spradling A.C. Genetic transformation of Drosophila with transposable element vectors. Science 218 (1982) 348-353
33. Scacheri P.C., Crabtree J.S., Kennedy A.L., Swain G.P., Ward J.M., Marx S.J., Spiegel A.M., and Collins F.S. Homozygous loss of menin is well tolerated in liver, a tissue not affected in MEN1. Mamm. Genome 15 (2004) 872-877
34. Tateno M., Nishida Y., and Adachi-Yamada T. Regulation of JNK by Src during Drosophila development. Science 287 (2000) 324-327
35. Yokoyama A., Wang Z., Wysocka J., Sanyal M., Aufiero D.J., Kitabayashi I., Herr W., and Cleary M.L. Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression. Mol. Cell. Biol. 24 (2004) 5639-5649
36. Yokoyama A., Somervaille T.C., Smith K.S., Rozenblatt-Rosen O., Meyerson M., and Cleary M.L. The menin tumor suppressor protein is an essential oncogenic cofactor for MLL-associated leukemogenesis. Cell 123 (2005) 207-218