-
1
-
-
0035873782
-
Identification of a selective nonpeptide antagonist of the anaphylatoxin C3a receptor that demonstrates antiinflammatory activity in animal models
-
Ames R.S., Lee D., Foley J.J., Jurewicz A.J., Tornetta M.A., Bautsch W., Settmacher B., Klos A., Erhard K.F., Cousins R.D., Sulpizio A.C., Hieble J.P., McCafferty G., Ward K.W., Adams J.L., Bondinell W.E., Underwood D.C., Osborn R.R., Badger A.M., and Sarau H.M. Identification of a selective nonpeptide antagonist of the anaphylatoxin C3a receptor that demonstrates antiinflammatory activity in animal models. J. Immunol. 166 (2001) 6341-6348
-
(2001)
J. Immunol.
, vol.166
, pp. 6341-6348
-
-
Ames, R.S.1
Lee, D.2
Foley, J.J.3
Jurewicz, A.J.4
Tornetta, M.A.5
Bautsch, W.6
Settmacher, B.7
Klos, A.8
Erhard, K.F.9
Cousins, R.D.10
Sulpizio, A.C.11
Hieble, J.P.12
McCafferty, G.13
Ward, K.W.14
Adams, J.L.15
Bondinell, W.E.16
Underwood, D.C.17
Osborn, R.R.18
Badger, A.M.19
Sarau, H.M.20
more..
-
2
-
-
0036794922
-
Astrocyte modulation of neurotoxic injury
-
Aschner M., Sonnewald U., and Tan K.H. Astrocyte modulation of neurotoxic injury. Brain Pathol. 12 (2002) 475-481
-
(2002)
Brain Pathol.
, vol.12
, pp. 475-481
-
-
Aschner, M.1
Sonnewald, U.2
Tan, K.H.3
-
4
-
-
33748776315
-
Characterization of C3a and C5a receptors in rat cerebellar granule neurons during maturation: neuroprotective effect of C5a against apoptotic cell death
-
Benard M., Gonzalez B.J., Schouft M.T., Falluel-Morel A., Vaudry D., Chan P., Vaudry H., and Fontaine M. Characterization of C3a and C5a receptors in rat cerebellar granule neurons during maturation: neuroprotective effect of C5a against apoptotic cell death. J. Biol. Chem. 2 (2004) 2
-
(2004)
J. Biol. Chem.
, vol.2
, pp. 2
-
-
Benard, M.1
Gonzalez, B.J.2
Schouft, M.T.3
Falluel-Morel, A.4
Vaudry, D.5
Chan, P.6
Vaudry, H.7
Fontaine, M.8
-
5
-
-
4644328027
-
Deletion of the complement anaphylatoxin c3a receptor attenuates, whereas ectopic expression of c3a in the brain exacerbates, experimental autoimmune encephalomyelitis
-
Boos L., Campbell I.L., Ames R., Wetsel R.A., and Barnum S.R. Deletion of the complement anaphylatoxin c3a receptor attenuates, whereas ectopic expression of c3a in the brain exacerbates, experimental autoimmune encephalomyelitis. J. Immunol. 173 (2004) 4708-4714
-
(2004)
J. Immunol.
, vol.173
, pp. 4708-4714
-
-
Boos, L.1
Campbell, I.L.2
Ames, R.3
Wetsel, R.A.4
Barnum, S.R.5
-
6
-
-
23644456320
-
C3a expressed in the central nervous system protects against LPS-induced shock
-
Boos L., Szalai A.J., and Barnum S.R. C3a expressed in the central nervous system protects against LPS-induced shock. Neurosci. Lett. 387 (2005) 68-71
-
(2005)
Neurosci. Lett.
, vol.387
, pp. 68-71
-
-
Boos, L.1
Szalai, A.J.2
Barnum, S.R.3
-
7
-
-
0033134789
-
Receptor for the C3a anaphylatoxin is expressed by neurons and glial cells
-
Davoust N., Jones J., Stahel P.F., Ames R.S., and Barnum S.R. Receptor for the C3a anaphylatoxin is expressed by neurons and glial cells. Glia 26 (1999) 201-211
-
(1999)
Glia
, vol.26
, pp. 201-211
-
-
Davoust, N.1
Jones, J.2
Stahel, P.F.3
Ames, R.S.4
Barnum, S.R.5
-
9
-
-
3242766671
-
Absence of C1q leads to less neuropathology in transgenic mouse models of Alzheimer's disease
-
Fonseca M.I., Zhou J., Botto M., and Tenner A.J. Absence of C1q leads to less neuropathology in transgenic mouse models of Alzheimer's disease. J. Neurosci. 24 (2004) 6457-6465
-
(2004)
J. Neurosci.
, vol.24
, pp. 6457-6465
-
-
Fonseca, M.I.1
Zhou, J.2
Botto, M.3
Tenner, A.J.4
-
10
-
-
0642333822
-
Complement C3a receptors in the pituitary gland: a novel pathway by which an innate immune molecule releases hormones involved in the control of inflammation
-
Epub 2003 Oct 16
-
Francis K., Lewis B.M., Akatsu H., Monk P.N., Cain S.A., Scanlon M.F., Morgan B.P., Ham J., and Gasque P. Complement C3a receptors in the pituitary gland: a novel pathway by which an innate immune molecule releases hormones involved in the control of inflammation. FASEB J. 17 (2003) 2266-2268 Epub 2003 Oct 16
-
(2003)
FASEB J.
, vol.17
, pp. 2266-2268
-
-
Francis, K.1
Lewis, B.M.2
Akatsu, H.3
Monk, P.N.4
Cain, S.A.5
Scanlon, M.F.6
Morgan, B.P.7
Ham, J.8
Gasque, P.9
-
11
-
-
0032055221
-
The receptor for complement anaphylatoxin C3a is expressed by myeloid cells and nonmyeloid cells in inflamed human central nervous system: analysis in multiple sclerosis and bacterial meningitis
-
Gasque P., Singhrao S.K., Neal J.W., Wang P., Sayah S., Fontaine M., and Morgan B.P. The receptor for complement anaphylatoxin C3a is expressed by myeloid cells and nonmyeloid cells in inflamed human central nervous system: analysis in multiple sclerosis and bacterial meningitis. J. Immunol. 160 (1998) 3543-3554
-
(1998)
J. Immunol.
, vol.160
, pp. 3543-3554
-
-
Gasque, P.1
Singhrao, S.K.2
Neal, J.W.3
Wang, P.4
Sayah, S.5
Fontaine, M.6
Morgan, B.P.7
-
12
-
-
0027954205
-
The pro-inflammatory seven-transmembrane segment receptors of the leukocyte
-
Gerard C., and Gerard N.P. The pro-inflammatory seven-transmembrane segment receptors of the leukocyte. Curr. Opin. Immunol. 6 (1994) 140-145
-
(1994)
Curr. Opin. Immunol.
, vol.6
, pp. 140-145
-
-
Gerard, C.1
Gerard, N.P.2
-
13
-
-
0034739041
-
A role for the C3a anaphylatoxin receptor in the effector phase of asthma
-
Humbles A.A., Lu B., Nilsson C.A., Lilly C., Israel E., Fujiwara Y., Gerard N.P., and Gerard C. A role for the C3a anaphylatoxin receptor in the effector phase of asthma. Nature 406 (2000) 998-1001
-
(2000)
Nature
, vol.406
, pp. 998-1001
-
-
Humbles, A.A.1
Lu, B.2
Nilsson, C.A.3
Lilly, C.4
Israel, E.5
Fujiwara, Y.6
Gerard, N.P.7
Gerard, C.8
-
14
-
-
0031741881
-
Expression of a functional anaphylatoxin C3a receptor by astrocytes
-
Ischenko A., Sayah S., Patte C., Andreev S., Gasque P., Schouft M.T., Vaudry H., and Fontaine M. Expression of a functional anaphylatoxin C3a receptor by astrocytes. J. Neurochem. 71 (1998) 2487-2496
-
(1998)
J. Neurochem.
, vol.71
, pp. 2487-2496
-
-
Ischenko, A.1
Sayah, S.2
Patte, C.3
Andreev, S.4
Gasque, P.5
Schouft, M.T.6
Vaudry, H.7
Fontaine, M.8
-
15
-
-
0034670027
-
Cutting edge: targeted disruption of the C3a receptor gene demonstrates a novel protective anti-inflammatory role for C3a in endotoxin-shock
-
Kildsgaard J., Hollmann T.J., Matthews K.W., Bian K., Murad F., and Wetsel R.A. Cutting edge: targeted disruption of the C3a receptor gene demonstrates a novel protective anti-inflammatory role for C3a in endotoxin-shock. J. Immunol. 165 (2000) 5406-5409
-
(2000)
J. Immunol.
, vol.165
, pp. 5406-5409
-
-
Kildsgaard, J.1
Hollmann, T.J.2
Matthews, K.W.3
Bian, K.4
Murad, F.5
Wetsel, R.A.6
-
16
-
-
0035047889
-
Complement facilitates early prion pathogenesis
-
Klein M.A., Kaeser P.S., Schwarz P., Weyd H., Xenarios I., Zinkernagel R.M., Carroll M.C., Verbeek J.S., Botto M., Walport M.J., Molina H., Kalinke U., Acha-Orbea H., and Aguzzi A. Complement facilitates early prion pathogenesis. Nat. Med. 7 (2001) 488-492
-
(2001)
Nat. Med.
, vol.7
, pp. 488-492
-
-
Klein, M.A.1
Kaeser, P.S.2
Schwarz, P.3
Weyd, H.4
Xenarios, I.5
Zinkernagel, R.M.6
Carroll, M.C.7
Verbeek, J.S.8
Botto, M.9
Walport, M.J.10
Molina, H.11
Kalinke, U.12
Acha-Orbea, H.13
Aguzzi, A.14
-
17
-
-
1642456624
-
Complement activation in human prion disease
-
Kovacs G.G., Gasque P., Strobel T., Lindeck-Pozza E., Strohschneider M., Ironside J.W., Budka H., and Guentchev M. Complement activation in human prion disease. Neurobiol. Dis. 15 (2004) 21-28
-
(2004)
Neurobiol. Dis.
, vol.15
, pp. 21-28
-
-
Kovacs, G.G.1
Gasque, P.2
Strobel, T.3
Lindeck-Pozza, E.4
Strohschneider, M.5
Ironside, J.W.6
Budka, H.7
Guentchev, M.8
-
18
-
-
23844553745
-
Characterization of the murine C3a receptor enhancer-promoter: expression control by an activator protein 1 sequence and an Ets-like site
-
Martin C.B., and Martin B.K. Characterization of the murine C3a receptor enhancer-promoter: expression control by an activator protein 1 sequence and an Ets-like site. J. Immunol. 175 (2005) 3123-3132
-
(2005)
J. Immunol.
, vol.175
, pp. 3123-3132
-
-
Martin, C.B.1
Martin, B.K.2
-
19
-
-
0035006284
-
Structure and biology of complement protein C3, a connecting link between innate and acquired immunity
-
Sahu A., and Lambris J.D. Structure and biology of complement protein C3, a connecting link between innate and acquired immunity. Immunol. Rev. 180 (2001) 35-48
-
(2001)
Immunol. Rev.
, vol.180
, pp. 35-48
-
-
Sahu, A.1
Lambris, J.D.2
-
20
-
-
0033011634
-
Expression of cytokines by human astrocytomas following stimulation by C3a and C5a anaphylatoxins: specific increase in interleukin-6 mRNA expression
-
Sayah S., Ischenko A.M., Zhakhov A., Bonnard A.S., and Fontaine M. Expression of cytokines by human astrocytomas following stimulation by C3a and C5a anaphylatoxins: specific increase in interleukin-6 mRNA expression. J. Neurochem. 72 (1999) 2426-2436
-
(1999)
J. Neurochem.
, vol.72
, pp. 2426-2436
-
-
Sayah, S.1
Ischenko, A.M.2
Zhakhov, A.3
Bonnard, A.S.4
Fontaine, M.5
-
21
-
-
0037430855
-
Two different transduction pathways are activated by C3a and C5a anaphylatoxins on astrocytes.
-
Sayah S., Jauneau A.C., Patte C., Tonon M.C., Vaudry H., and Fontaine M. Two different transduction pathways are activated by C3a and C5a anaphylatoxins on astrocytes. Brain Res. Mol. Brain Res. 112 (2003) 53-60
-
(2003)
Brain Res. Mol. Brain Res.
, vol.112
, pp. 53-60
-
-
Sayah, S.1
Jauneau, A.C.2
Patte, C.3
Tonon, M.C.4
Vaudry, H.5
Fontaine, M.6
-
22
-
-
29644447200
-
The transcription factors AP-1 and Ets are regulators of C3a receptor expression
-
Epub 2005 Oct 27
-
Schaefer M., Konrad S., Thalmann J., Rheinheimer C., Johswich K., Sohns B., and Klos A. The transcription factors AP-1 and Ets are regulators of C3a receptor expression. J. Biol. Chem. 280 (2005) 42113-42123 Epub 2005 Oct 27
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 42113-42123
-
-
Schaefer, M.1
Konrad, S.2
Thalmann, J.3
Rheinheimer, C.4
Johswich, K.5
Sohns, B.6
Klos, A.7
-
23
-
-
0032873347
-
Increased complement biosynthesis by microglia and complement activation on neurons in Huntington's disease
-
Singhrao S.K., Neal J.W., Morgan B.P., and Gasque P. Increased complement biosynthesis by microglia and complement activation on neurons in Huntington's disease. Exp. Neurol. 159 (1999) 362-376
-
(1999)
Exp. Neurol.
, vol.159
, pp. 362-376
-
-
Singhrao, S.K.1
Neal, J.W.2
Morgan, B.P.3
Gasque, P.4
-
24
-
-
0032904682
-
Phagocytosis of myelin in demyelinative disease: a review
-
Smith M.E. Phagocytosis of myelin in demyelinative disease: a review. Neurochem. Res. 24 (1999) 261-268
-
(1999)
Neurochem. Res.
, vol.24
, pp. 261-268
-
-
Smith, M.E.1
-
25
-
-
0035879567
-
Phagocytic properties of microglia in vitro: implications for a role in multiple sclerosis and EAE
-
Smith M.E. Phagocytic properties of microglia in vitro: implications for a role in multiple sclerosis and EAE. Microsc. Res. Tech. 54 (2001) 81-94
-
(2001)
Microsc. Res. Tech.
, vol.54
, pp. 81-94
-
-
Smith, M.E.1
-
26
-
-
0032403504
-
Astrocytes express elements of the class II endocytic pathway and process central nervous system autoantigen for presentation to encephalitogenic T cells
-
Soos J.M., Morrow J., Ashley T.A., Szente B.E., Bikoff E.K., and Zamvil S.S. Astrocytes express elements of the class II endocytic pathway and process central nervous system autoantigen for presentation to encephalitogenic T cells. J. Immunol. 161 (1998) 5959-5966
-
(1998)
J. Immunol.
, vol.161
, pp. 5959-5966
-
-
Soos, J.M.1
Morrow, J.2
Ashley, T.A.3
Szente, B.E.4
Bikoff, E.K.5
Zamvil, S.S.6
-
28
-
-
0031019547
-
Indictment of the microglia as the villain in multiple sclerosis
-
Sriram S., and Rodriguez M. Indictment of the microglia as the villain in multiple sclerosis. Neurology 48 (1997) 464-470
-
(1997)
Neurology
, vol.48
, pp. 464-470
-
-
Sriram, S.1
Rodriguez, M.2
-
29
-
-
0141449968
-
The proinflammatory mediators C3a and C5a are essential for liver regeneration
-
Strey C.W., Markiewski M., Mastellos D., Tudoran R., Spruce L.A., Greenbaum L.E., and Lambris J.D. The proinflammatory mediators C3a and C5a are essential for liver regeneration. J. Exp. Med. 198 (2003) 913-923
-
(2003)
J. Exp. Med.
, vol.198
, pp. 913-923
-
-
Strey, C.W.1
Markiewski, M.2
Mastellos, D.3
Tudoran, R.4
Spruce, L.A.5
Greenbaum, L.E.6
Lambris, J.D.7
-
30
-
-
0034052110
-
Expression of receptors for complement anaphylatoxins C3a and C5a following permanent focal cerebral ischemia in the mouse
-
Van Beek J., Bernaudin M., Petit E., Gasque P., Nouvelot A., MacKenzie E.T., and Fontaine M. Expression of receptors for complement anaphylatoxins C3a and C5a following permanent focal cerebral ischemia in the mouse. Exp. Neurol. 161 (2000) 373-382
-
(2000)
Exp. Neurol.
, vol.161
, pp. 373-382
-
-
Van Beek, J.1
Bernaudin, M.2
Petit, E.3
Gasque, P.4
Nouvelot, A.5
MacKenzie, E.T.6
Fontaine, M.7
-
31
-
-
0035847643
-
Complement anaphylatoxin C3a is selectively protective against NMDA-induced neuronal cell death
-
van Beek J., Nicole O., Ali C., Ischenko A., MacKenzie E.T., Buisson A., and Fontaine M. Complement anaphylatoxin C3a is selectively protective against NMDA-induced neuronal cell death. Neuroreport 12 (2001) 289-293
-
(2001)
Neuroreport
, vol.12
, pp. 289-293
-
-
van Beek, J.1
Nicole, O.2
Ali, C.3
Ischenko, A.4
MacKenzie, E.T.5
Buisson, A.6
Fontaine, M.7
-
32
-
-
0032619953
-
Mapping protein-DNA interactions using in vivo footprinting
-
Warshawsky D., and Miller L. Mapping protein-DNA interactions using in vivo footprinting. Meth. Mol. Biol. 127 (1999) 199-212
-
(1999)
Meth. Mol. Biol.
, vol.127
, pp. 199-212
-
-
Warshawsky, D.1
Miller, L.2
|