Subchronic chloroform priming protects mice from a subsequently administered lethal dose of chloroform

Toxicology and Applied Pharmacology

Volumn 216, Issue 1, 2006, Pages 108-121

  Philip, Binu K ^a   Anand, Sathanandam S ^a   Palkar, Prajakta S ^a   Mumtaz, Moiz M ^b   Latendresse, John R ^c   Mehendale, Harihara M ^a  

^a UNIVERSITY OF LOUISIANA AT MONROE   (United States)

^b AGENCY FOR TOXIC SUBSTANCES AND DISEASE REGISTRY   (United States)

^c Toxicologic Pathology Associates   (United States)

Author keywords

Autoprotection; Chloroform; Kidney injury; Liver injury; Subchronic exposure; Swiss Webster mice; Tissue repair

Indexed keywords

BUTHIONINE SULFOXIMINE; CHLOROFORM; CHLOROFORM C 14; CYTOCHROME P450 2E1; GLUTATHIONE; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ANIMAL CELL; ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; COVALENT BOND; DETOXIFICATION; KIDNEY CLEARANCE; KIDNEY INJURY; LETHAL DOSE; LIVER REGENERATION; LIVER TOXICITY; MALE; MORTALITY; MOUSE; MULTIPLE ORGAN FAILURE; NEPHROTOXICITY; NONHUMAN; SURVIVAL RATE; SYSTEMIC CIRCULATION; TIME; TISSUE REGENERATION; URINARY EXCRETION; WATER CONTAMINATION;

ALANINE TRANSAMINASE; ANIMALS; AREA UNDER CURVE; BUTHIONINE SULFOXIMINE; CHLOROFORM; CYTOCHROME P-450 CYP2E1; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG TOLERANCE; DRUG-INDUCED LIVER INJURY; GLUTATHIONE; GLUTATHIONE REDUCTASE; HEPATOCYTES; INTUBATION, GASTROINTESTINAL; KIDNEY; KIDNEY DISEASES; LIVER DISEASES; MICE; SURVIVAL RATE;

EID: 33748754715     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2006.04.012     Document Type: Article

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