Toxicity and behavioral effects of dimethylsulfoxide in planaria

Neuroscience Letters

Volumn 407, Issue 3, 2006, Pages 274-278

  Pagán, Oné R ^a   Rowlands, Amanda L ^a   Urban, Kimberly R ^a  

^a WEST CHESTER UNIVERSITY   (United States)

Author keywords

Artificial pond water; Dimethylsulfoxide; DMSO; Motility; Planaria; Toxicity

Indexed keywords

DIMETHYL SULFOXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; AQUEOUS SOLUTION; ARTICLE; BEHAVIOR; BEHAVIOR CHANGE; CONCENTRATION RESPONSE; EXPLORATORY BEHAVIOR; EXPOSURE; HYDROPHOBICITY; LD 50; LOCOMOTION; MOTOR DYSFUNCTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; TURBELLARIA; WORM;

ANIMALS; BEHAVIOR, ANIMAL; CRYOPROTECTIVE AGENTS; DIMETHYL SULFOXIDE; LETHAL DOSE 50; PLANARIANS; SOLVENTS;

EID: 33748754711     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2006.08.073     Document Type: Article

References (33)

1. Anchordoguy T.J., Carpenter J.F., Crowe J.H., and Crowe L.M. Temperature-dependent perturbation of phospholipid bilayers by dimethylsulfoxide. Biochim. Biophys. Acta 1104 (1992) 117-122
2. Anderson G.L., Cole R.D., and Williams L. Assessing behavioral toxicity with Caenorhabditis elegans. Environ. Toxicol. Chem. 23 (2004) 1235-1240
3. Balakin K.V., Saychuk N.P., and Tetko I.V. In silico approaches to prediction of aqueous and DMSO solubility of drug-like compounds: trends, problems and solutions. Curr. Med. Chem. 13 (2006) 223-241
4. Buttarelli F.R., Pontieri F.E., Margotta V., and Palladini G. Acetylcholine/dopamine interaction in planaria. Comp. Biochem. Physiol. C Toxicol. Pharmacol. 125 (2000) 225-231
5. Buttarelli F.R., Pontieri F.E., Margotta V., and Palladini G. Cannabinoid-induced stimulation of motor activity in planaria through an opioid receptor-mediated mechanism. Prog. Neuropsychopharmacol. Biol. Psychiatry 26 (2002) 65-68
6. Castroman P.J., and Ness T.J. Spinal neurophysiologic correlates of the analgesic actions of intravesical dimethyl sulfoxide and capsaicin in the rat. J. Pain 3 (2002) 394-400
7. Evans M.S., Reid K.H., and Sharp J.B. Dimethylsulfoxide (DMSO) blocks conduction in peripheral nerve C fibers: a possible mechanism of analgesia. Neurosci. Lett. 150 (1993) 145-148
8. Grebe E., and Schaeffer D.J. Planarians in toxicology, standardization of a rapid neurobehavioral toxicity test using phenol in a crossover study. Bull. Environ. Contam. Toxicol. 46 (1991) 866-870
9. Jacob S.W., and Herschler R. Pharmacology of DMSO. Cryobiology 24 (1986) 4-27
10. Kang S.N., Kim S.H., Chung S.W., Lee M.H., Kim H.J., and Kim T.S. Enhancement of 1 alpha, 25-dihydroxyvitamin D(3)-induced differentiation of human leukaemia HL-60 cells into monocytes by parthenolide via inhibition of NF-kappa B activity. Br. J. Pharmacol. 135 (2002) 1235-1244
11. Kimmel H.D., and Carlyon W.D. Persistent effects of a serotonin depletor (p-chlorophenylalanine) in regenerated planaria (Dugesia dorotocephala). Behav. Neurosci. 104 (1990) 127-134
12. Kubota K., Fujibayashi K., and Saito K. Enhancing effect of dimethylsulfoxide on nociceptive transmission in isolated spinal cord of newborn rat. Eur. J. Pharmacol. 351 (1998) 173-179
13. Kusayama T., and Watanabe S. Reinforcing effects of methamphetamine in planarians. Neuroreport 11 (2000) 2511-2513
14. Larsen J., Gasser K., and Hahin R. An analysis of dimethylsulfoxide-induced action potential block: a comparative study of DMSO and other aliphatic water soluble solutes. Toxicol. Appl. Pharmacol. 140 (1996) 296-314
15. Lowrie R.C., and Eberhard M.L. A new technique for immobilizing filaria larvae using dimethyl sulfoxide (DMSO). J. Parasitol. 66 (1980) 169-170
16. Lu C., and Mattson M.P. Dimethyl sulfoxide suppresses NMDA- and AMPA-induced ion currents and calcium influx and protects against excitotoxic death in hippocampal neurons. Exp. Neurol. 170 (2001) 180-185
17. Nakahiro M., Arakawa O., Narahashi T., Ukai S., Kato Y., Nishinuma K., and Nishimura T. Dimethyl sulfoxide (DMSO) blocks GABA-induced current in rat dorsal root ganglion neurons. Neurosci. Lett. 138 (1992) 5-8
18. Newmark P.A., and Sanchez-Alvarado A. Not your father's planarian: a classic model enters the era of functional genomics. Nat. Rev. Genet. 3 (2002) 210-219
19. Passarelli F., Merante A., Pontieri F.E., Margotta V., Venturini G., and Palladini G. Opioid-dopamine interaction in planaria: a behavioral study. Comp. Biochem. Physiol. C Pharmacol. Toxicol. Endocrinol. 124 (1999) 51-55
20. Raffa R.B., and Desai P. Description and quantification of cocaine withdrawal signs in Planaria. Brain Res. 1032 (2005) 200-202
21. Raffa R.B., Holland L.J., and Schulingkamp R.J. Quantitative assessment of dopamine D2 antagonist activity using invertebrate (Planaria) locomotion as a functional endpoint. J. Pharmacol. Toxicol. Methods 45 (2001) 223-226
22. Raffa R.B., Stagliano G.W., and Umeda S. Kappa-Opioid withdrawal in Planaria. Neurosci. Lett. 349 (2003) 139-142
23. Reddien P.W., and Sanchez-Alvarado A. Fundamentals of planarian regeneration. Annu. Rev. Cell Dev. Biol. 20 (2004) 725-757
24. Rosenblum W.I., Wei E.P., and Kontos H.A. Dimethylsulfoxide and ethanol, commonly used diluents, prevent dilation of pial arterioles by openers of K(ATP) ion channels. Eur. J. Pharmacol. 430 (2001) 101-106
25. Sarnat H.B., and Netsky M.G. When does a ganglion become a brain? Evolutionary origin of the central nervous system. Semin. Pediatr. Neurol. 9 (2002) 240-253
26. Schaeffer D.J. Planarians as a model system for in vivo teratogenesis studies. Qual. Assur. 2 (1993) 265-318
27. Somei K., Mizuma K., Nara K., Matsuya H., Yoda J., Sasaki K., and Kashimoto T. Dimethylsulfoxide potentiates the suppressive effects of lidocaine on synaptic transmission in bullfrog sympathetic ganglion. Methods Find. Exp. Clin. Pharmacol. 17 (1995) 571-576
28. Sum A.K., and DePablo J.J. Molecular simulation study on the influence of dimethylsulfoxide on the structure of phospholipid bilayers. Biophys. J. 85 (2003) 3636-3645
29. Theophilidis G., and Kravari K. Dimethylsulfoxide (DMSO) eliminates the response of the sensory neurones of an insect mechanoreceptor, the femoral chordotonal organ of Locusta migratoria, but blocks conduction of their sensory axons at much higher concentrations: a possible mechanism of analgesia. Neurosci. Lett. 7 (1994) 91-94
30. Villar D., and Schaeffer D.J. Morphogenetic action of neurotransmitters on regenerating planarians-a review. Biomed. Environ. Sci. 6 (1993) 327-347
31. Villas-Boas A., Fontes C.F., Norby J.G., and Barrabin H. Dimethyl sulfoxide-induced conformational state of Na(+)/K(+)-ATPase studied by proteolytic cleavage. Arch. Biochem. Biophys. 399 (2002) 89-95
32. Weiss J.N. The Hill equation revisited: uses and misuses. FASEB J. 11 (1997) 835-841
33. Yu Z.W., and Quinn P.J. Dimethyl sulphoxide: a review of its applications in cell biology. Biosci. Rep. 14 (1994) 259-281