Synthesis, conformational analysis and CB1 binding affinity of hairpin-like anandamide pseudopeptide mimetics

Journal of Peptide Science

Volumn 12, Issue 9, 2006, Pages 575-591

  Di Marzo, Maria ^a   Casapullo, Agostino ^a   Bifulco, Giuseppe ^a   Cimino, Paola ^a   Ligresti, Alessia ^b   Di Marzo, Vincenzo ^b   Riccio, Raffaele ^a   Gomez Paloma, Luigi ^a  

^a UNIVERSITY OF SALERNO   (Italy)

^b CNR   (Italy)

Author keywords

Anandamide; Cannabinoids; Conformational analysis; Solid phase peptide synthesis

Indexed keywords

ANANDAMIDE; ANANDAMIDE DERIVATIVE; CANNABINOID 1 RECEPTOR; LIPOPEPTIDE; PSEUDOPEPTIDE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING ASSAY; CALCULATION; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG CONFORMATION; DRUG DESIGN; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; THREE DIMENSIONAL IMAGING;

AMINO ACID SEQUENCE; ANIMALS; ARACHIDONIC ACIDS; BINDING SITES; ENDOCANNABINOIDS; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MODELS, MOLECULAR; MOLECULAR MIMICRY; MOLECULAR SEQUENCE DATA; POLYUNSATURATED ALKAMIDES; RATS; RECEPTOR, CANNABINOID, CB1; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33748752236     PISSN: 10752617     EISSN: 10991387     Source Type: Journal    
DOI: 10.1002/psc.754     Document Type: Article

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