Ex-Vivo Perfusion and Ventilation of Rat Lungs From Non-Heart-Beating Donors Before Transplant

Annals of Thoracic Surgery

Volumn 82, Issue 4, 2006, Pages 1219-1225

  Inokawa, Hidetoshi ^a   Sevala, Mayura ^b   Funkhouser, William K ^b   Egan, Thomas M ^b  

^a OKAYAMA UNIVERSITY   (Japan)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKADIENE; MYELOPEROXIDASE;

ANIMAL TISSUE; ARTERIAL GAS; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; CRYOPRESERVATION; CRYSTALLOID; DONOR; DRY WEIGHT; ERYTHROCYTE; HEMATOCRIT; LUNG COMPLIANCE; LUNG FUNCTION; LUNG GAS EXCHANGE; LUNG PERFUSION; LUNG TRANSPLANTATION; LUNG VENTILATION; MECHANICAL PROBE; NONHUMAN; PRIORITY JOURNAL; PULMONARY ARTERY; PULMONARY VEIN; RAT; TEMPERATURE; VASCULAR RESISTANCE;

ANIMALS; COLD ISCHEMIA; LUNG; LUNG TRANSPLANTATION; MODELS, ANIMAL; ORGAN PRESERVATION; PERFUSION; RATS; RATS, SPRAGUE-DAWLEY; RESPIRATION, ARTIFICIAL; TISSUE DONORS;

EID: 33748751383     PISSN: 00034975     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.athoracsur.2006.05.004     Document Type: Article

References (30)

1. Egan T.M., Lambert Jr. C.J., Reddick R.L., Ulicny Jr. K.S., Keagy B.A., and Wilcox B.R. A strategy to increase the donor pool: the use of cadaver lungs for transplantation. Ann Thorac Surg 52 (1991) 1113-1121
2. Ulicny Jr. K.S., Egan T.M., Lambert Jr. C.J., Reddick R.L., and Wilcox B.R. Cadaver lung donors: effect of preharvest ventilation on graft function. Ann Thorac Surg 55 (1993) 1185-1191
3. Roberts C.S., D'Armini A.M., and Egan T.M. Canine double-lung transplantation with cadaver donors. J Thorac Cardiovasc Surg 112 (1996) 577-583
4. Kiser A., Ciriaco P., Hoffmann S., and Egan T. Lung retrieval from non-heart beating cadavers with the use of a rat lung transplant model. J Thorac Cardiovasc Surg 122 (2001) 18-23
5. Egan T. Non-heart-beating donors in thoracic transplantation. J Heart Lung Transplant 23 (2004) 3-10
6. Buchanan S.A., DeLima N.F., Binns O.A.R., et al. Pulmonary function after non-heart-beating lung donation in a survival model. Ann Thorac Surg 60 (1995) 38-46
7. Loehe F., Mueller C., Annecke T., et al. Pulmonary graft function after long-term preservation of non-heart-beating donor lungs. Ann Thorac Surg 69 (2000) 1556-1562
8. Tremblay L.N., Yamashiro T., DeCampos K.N., et al. Effect of hypotension preceding death on the function of lungs from donors with nonbeating hearts. J Heart Lung Transplant 15 (1996) 260-268
9. Steen S., Liao Q., Wierup P.N., Bolys R., Pierre L., and Sjöberg T. Transplantation of lungs from non-heart-beating donors after functional assessment ex vivo. Ann Thorac Surg 76 (2003) 244-252
10. Steen S., Sjoberg T., Pierre L., Liao Q., Eriksson L., and Algotsson L. Transplantation of lungs from a non-heart beating donor. Lancet 357 (2001) 825-829
11. Aitchison J.D., Orr H.E., Flecknell P.A., Kirby J.A., and Dark J.H. Functional assessment of non-heart-beating donor lungs: prediction of post-transplant function. Eur J Cardiothorac Surg 20 (2001) 187-194
12. Rega F.R., Jannis N.C., Verleden G.M., Flameng W.J., Lerut T.E., and Van Raemdonck D.E. Should we ventilate or cool the pulmonary graft inside the non-heart-beating donor?. J Heart Lung Transplant 22 (2003) 1226-1233
13. Egan T.M., Haithcock J.A., Nicotra W.A., et al. Ex-vivo evaluation of human lungs for transplant suitability. Ann Thorac Surg 81 (2006) 1205-1213
14. Jones D.R., Becker R.M., Hoffmann S.C., Lemasters J.J., and Egan T.M. When does the lung die?. Kfc, cell viability, and adenine nucleotide changes in the circulation-arrested rat lung. J Appl Physiol 83 (1997) 247-252
15. Jones D.R., Hoffmann S.C., Sellars M., and Egan T.M. Reduced ischemia-reperfusion injury with isoproterenol in non-heart-beating donor lungs. J Surg Res 69 (1997) 385-392
16. Bleiweis M.S., Jones D.R., Hoffmann S.C., Becker R.M., and Egan T.M. Reduced ischemia-reperfusion injury with rolipram in rat cadaver lung donors: effect of cAMP?. Ann Thorac Surg 67 (1999) 194-200
17. Hoffmann S., Bleiweis M., Jones D., Paik H., Ciriaco P., and Egan T. Maintenance of cAMP in non-heart beating donor lungs reduces ischemia-reperfusion injury. Am J Resp Crit Care Med 163 (2001) 1642-1647
18. Paik H.C., Hoffmann S.C., and Egan T.M. Pulmonary preservation studies: effects on endothelial function and pulmonary adenine nucleotides. Transplantation 75 (2003) 439-444
19. Takashima S., Schlidt S.A., Koukoulis G., Sevala M., and Egan T.M. Isoproterenol reduces ischemia-reperfusion lung injury despite β-blockade. J Surg Res 126 (2005) 114-120
20. Egan T., Thomas Y., Gibson D., et al. Trigger for intercellular adhesion molecule-1 expression in rat lungs transplanted from non-heart-beating donors. Ann Thorac Surg 77 (2004) 1048-1055
21. Gregory T.R. Nucleotypic effects without nuclei: genome size and erythrocyte size in mammals. Genome 43 (2000) 895-901
22. de Perrot M., Quadri S.M., Imai Y., and Keshavjee S. Independent ventilation of the graft and native lungs in vivo after rat lung transplantation. Ann Thorac Surg 79 (2005) 2169-2171
23. 14C: significance for study of the pathology of lipid peroxidation. Lipids 12 (1977) 914-921
24. Aitchison J.D., Orr H.E., Flecknell P.A., Kirby J.A., and Dark J.H. Nitric oxide during perfusion improves posttransplantation function of non-heart-beating donor lungs. Transplantation 75 (2003) 1960-1964
25. Murry C.E., Jennings R.B., and Reimer K.A. Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. Circulation 74 (1986) 1124-1136
26. Friedrich I., Spillner J., Er-Xiong L., et al. Ischemic pre-conditioning of 5 minutes but not of 10 minutes improves lung function after warm ischemia in a canine model. J Heart Lung Transplant 20 (2001) 985-995
27. Du Z.Y., Hicks M., Winlaw D., Spratt P., and Macdonald P. Ischemic preconditioning enhances donor lung preservation in the rat. J Heart Lung Transplant 15 (1996) 1258-1267
28. Love R.B., D'Alessandro A.M., Cornwell R.A., and Meyer K.M. Ten year experience with human lung transplantation from non-heart beating donors. (Abstract). J Heart Lung Transplant 22 (2003) S87
29. Gomez de Antonio D., Laporta R., Mora G., et al. Mid-term results with non-heart-beating donors lung transplantation. (Abstract). J Heart Lung Transplant 25 (2006) S108
30. Van Raemdonck D.E., Rega F.R., Neyrinck A.P., Jannis N., Verleden G.M., and Lerut T.E. Non-heart-beating donors. Semin Thorac Cardiovasc Surg 16 (2004) 309-321