-
1
-
-
33744792341
-
Enterocolitis in patients with cancer after antibody blockade of cytotoxic T-lymphocyte-associated antigen 4
-
Beck KE, Blansfield JA, Tran KQ, Feldman AL, Hughes MS, Royal RE, Kammula US, Topalian SL, Sherry RM, Kleiner D, Quezado M, Lowy I, Yellin M, Rosenberg SA, Yang JC. Enterocolitis in patients with cancer after antibody blockade of cytotoxic T-lymphocyte-associated antigen 4. J Clin Oncol 2006; 24: 2283-9.
-
(2006)
J Clin Oncol
, vol.24
, pp. 2283-2289
-
-
Beck, K.E.1
Blansfield, J.A.2
Tran, K.Q.3
Feldman, A.L.4
Hughes, M.S.5
Royal, R.E.6
Kammula, U.S.7
Topalian, S.L.8
Sherry, R.M.9
Kleiner, D.10
Quezado, M.11
Lowy, I.12
Yellin, M.13
Rosenberg, S.A.14
Yang, J.C.15
-
2
-
-
27444440093
-
Cytotoxic T-lymphocyte-associated antigen-4 blockage can induce autoimmune hypophysitis in patients with metastatic melanoma and renal cancer
-
Blansfield JA, Beck KE, Tran K, Yang JC, Hughes MS, Kammula US, Royal RE, Topalian SL, Haworth LR, Levy C, Rosenberg SA, Sherry RM. Cytotoxic T-lymphocyte-associated antigen-4 blockage can induce autoimmune hypophysitis in patients with metastatic melanoma and renal cancer. J Immunother 2005; 28: 593-8.
-
(2005)
J Immunother
, vol.28
, pp. 593-598
-
-
Blansfield, J.A.1
Beck, K.E.2
Tran, K.3
Yang, J.C.4
Hughes, M.S.5
Kammula, U.S.6
Royal, R.E.7
Topalian, S.L.8
Haworth, L.R.9
Levy, C.10
Rosenberg, S.A.11
Sherry, R.M.12
-
3
-
-
0038153907
-
Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma
-
Phan GQ, Yang JC, Sherry RM Hwu P, Topalian SL, Schwartzentruber DJ, Restifo NP, Haworth LR, Seipp CA, Freezer LJ, Morton KE, Mavroukakis SA, Duray PH, Steinberg SM, Allison JP, Davis TA, Rosenberg SA. Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma. Proc Natl Acad Sci USA 2003; 100: 8372-7.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 8372-8377
-
-
Phan, G.Q.1
Yang, J.C.2
Sherry, R.M.3
Hwu, P.4
Topalian, S.L.5
Schwartzentruber, D.J.6
Restifo, N.P.7
Haworth, L.R.8
Seipp, C.A.9
Freezer, L.J.10
Morton, K.E.11
Mavroukakis, S.A.12
Duray, P.H.13
Steinberg, S.M.14
Allison, J.P.15
Davis, T.A.16
Rosenberg, S.A.17
-
5
-
-
33646946169
-
Clinical pharmacology - The first 75 years and a view of the future
-
Dollery CT. Clinical pharmacology - the first 75 years and a view of the future. Br J Clin Pharmacol 2006; 61: 650-65.
-
(2006)
Br J Clin Pharmacol
, vol.61
, pp. 650-665
-
-
Dollery, C.T.1
-
6
-
-
33644845414
-
Clinical pharmacology - Too young to die?
-
Maxwell SR, Webb DJ. Clinical pharmacology - too young to die? Lancet 2006; 367:799-800.
-
(2006)
Lancet
, vol.367
, pp. 799-800
-
-
Maxwell, S.R.1
Webb, D.J.2
-
7
-
-
0033954691
-
Researchers and regulators reflect on first gene therapy death
-
Hollon T. Researchers and regulators reflect on first gene therapy death. Nat Med 2000; 6: 6.
-
(2000)
Nat Med
, vol.6
, pp. 6
-
-
Hollon, T.1
-
9
-
-
33744922424
-
TGN1412: Time to change the paradigm for the testing of new pharmaceuticals
-
Bhogal N, Combes R. TGN1412: time to change the paradigm for the testing of new pharmaceuticals. Altern Lab Anim 2006; 34: 225-39.
-
(2006)
Altern Lab Anim
, vol.34
, pp. 225-239
-
-
Bhogal, N.1
Combes, R.2
-
11
-
-
33645504676
-
Learning from the TGN1412 trial
-
Goodyear M. Learning from the TGN1412 trial. BMJ 2006; 332: 677-8.
-
(2006)
BMJ
, vol.332
, pp. 677-678
-
-
Goodyear, M.1
-
12
-
-
33744991740
-
TGN1412: Scrutinizing preclinical trials of antibody-based medicines
-
Hansen S, Leslie RG. TGN1412: scrutinizing preclinical trials of antibody-based medicines. Nature 2006; 441: 282.
-
(2006)
Nature
, vol.441
, pp. 282
-
-
Hansen, S.1
Leslie, R.G.2
-
14
-
-
33749648484
-
Determining risk in human experimentation with drugs. Lessons from TGN1412
-
in press
-
Cohen AF, Kenter MJH. Determining risk in human experimentation with drugs. Lessons from TGN1412. Lancet 2006; in press.
-
(2006)
Lancet
-
-
Cohen, A.F.1
Kenter, M.J.H.2
-
15
-
-
33645504676
-
Learning from the TGN1412 trial
-
Goodyear M. Learning from the TGN1412 trial. BMJ 2006; 332: 677-8.
-
(2006)
BMJ
, vol.332
, pp. 677-678
-
-
Goodyear, M.1
-
17
-
-
28244483121
-
Physiologically based pharmacokinetic modelling: A sound mechanistic basis is needed
-
Aarons L. Physiologically based pharmacokinetic modelling: a sound mechanistic basis is needed. Br J Clin Pharmacol 2005; 60: 581-3.
-
(2005)
Br J Clin Pharmacol
, vol.60
, pp. 581-583
-
-
Aarons, L.1
-
18
-
-
33748746652
-
Prescribed doses of inhaled steroids in Dutch children: Too little or too much, for too short a time
-
Schirm E, de Vries T, Tobi H, van den Berg P, De Jong-van Den Berg L. Prescribed doses of inhaled steroids in Dutch children: too little or too much, for too short a time. Br J Clin Pharmacol 2006; 62: 383-90.
-
(2006)
Br J Clin Pharmacol
, vol.62
, pp. 383-390
-
-
Schirm, E.1
De Vries, T.2
Tobi, H.3
Van Den Berg, P.4
De Jong-van Den Berg, L.5
-
19
-
-
33748744038
-
Speed of onset of bronchodilator response to salbutamol inhaled via different devices in asthmatics: A bioassay based upon functional antagonism
-
Lavorini F, Geri P, Mariani C, Maluccio NM, Pistolesi M, Fontana GA. Speed of onset of bronchodilator response to salbutamol inhaled via different devices in asthmatics: a bioassay based upon functional antagonism. Br J Clin Pharmacol 2006; 62: 403-11.
-
(2006)
Br J Clin Pharmacol
, vol.62
, pp. 403-411
-
-
Lavorini, F.1
Geri, P.2
Mariani, C.3
Maluccio, N.M.4
Pistolesi, M.5
Fontana, G.A.6
-
20
-
-
33748748971
-
Plasma concentrations of inhaled corticosteroids in relation to airflow obstruction in asthma
-
Mortimer K, Harrison TW, Tang Y, Wu K, Lewis S, Sahasranaman S, Hochhaus G, Tattersfield A. Plasma concentrations of inhaled corticosteroids in relation to airflow obstruction in asthma. Br J Clin Pharmacol 2006; 62: 412-9.
-
(2006)
Br J Clin Pharmacol
, vol.62
, pp. 412-419
-
-
Mortimer, K.1
Harrison, T.W.2
Tang, Y.3
Wu, K.4
Lewis, S.5
Sahasranaman, S.6
Hochhaus, G.7
Tattersfield, A.8
-
22
-
-
33748741362
-
Pharmacokinetics of subcutaneously administered etanercept in subjects with psoriasis
-
Nestorov I, Zitnik R, DeVries T, Nakamishi AM, Wang A, Banfield C. Pharmacokinetics of subcutaneously administered etanercept in subjects with psoriasis. Br J Clin Pharmacol 2006; 62: 435-45.
-
(2006)
Br J Clin Pharmacol
, vol.62
, pp. 435-445
-
-
Nestorov, I.1
Zitnik, R.2
DeVries, T.3
Nakamishi, A.M.4
Wang, A.5
Banfield, C.6
-
23
-
-
33748752301
-
Risk of hospitalisation for angio-oedema among users of newer COX-2 selective inhibitors and other non-steroidal ant-inflammatory drugs
-
Downing A, Jacobsen J, Toft Sorensen H, McLaughlin J K, Johnsen SP. Risk of hospitalisation for angio-oedema among users of newer COX-2 selective inhibitors and other non-steroidal ant-inflammatory drugs. Br J Clin Pharmacol 2006; 62: 496-501.
-
(2006)
Br J Clin Pharmacol
, vol.62
, pp. 496-501
-
-
Downing, A.1
Jacobsen, J.2
Toft Sorensen, H.3
McLaughlin, J.K.4
Johnsen, S.P.5
-
24
-
-
33748756586
-
After the London tragedy, is it still possible to consider Phase I is safe?
-
Sibille M, Donazzolo Y, Lecoz F, Krupka E. After the London tragedy, is it still possible to consider Phase I is safe? Br J Clin Pharmacol 2006; 62: 502-3.
-
(2006)
Br J Clin Pharmacol
, vol.62
, pp. 502-503
-
-
Sibille, M.1
Donazzolo, Y.2
Lecoz, F.3
Krupka, E.4
|