Chromosomal alterations in 98 endometrioid adenocarcinomas analyzed with comparative genomic hybridization

Cytogenetic and Genome Research

Volumn 115, Issue 1, 2006, Pages 16-22

  Levan, K ^a   Partheen, K ^a   Osterberg L ^a   Helou, K ^a   Horvath, G ^a,b  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; CANCER CYTODIAGNOSIS; CANCER INVASION; CANCER PATIENT; CANCER STAGING; CANCER SURVIVAL; CHROMOSOME 10P; CHROMOSOME 13P; CHROMOSOME 13Q; CHROMOSOME 19P; CHROMOSOME 19Q; CHROMOSOME 1Q; CHROMOSOME 21Q; CHROMOSOME 22Q; CHROMOSOME 8Q; CHROMOSOME ABERRATION; CHROMOSOME ANALYSIS; CHROMOSOME DELETION; COMPARATIVE GENOMIC HYBRIDIZATION; ENDOMETRIUM CARCINOMA; EVALUATION; FEMALE; GENETIC ANALYSIS; GENETIC VARIABILITY; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; METASTASIS; PRIORITY JOURNAL; SAMPLING; SURVIVAL RATE;

CARCINOMA, ENDOMETRIOID; CHROMOSOME ABERRATIONS; ENDOMETRIAL NEOPLASMS; FEMALE; GENE DOSAGE; HUMANS; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; NEOPLASM STAGING; NUCLEIC ACID HYBRIDIZATION; SURVIVAL RATE;

EID: 33748744696     PISSN: 14248581     EISSN: None     Source Type: Journal    
DOI: 10.1159/000094796     Document Type: Article

References (32)

1. Bamberger AM, Bamberger CM, Gellersen B, Schulte HM: Modulation of AP-1 activity by the human progesterone receptor in endometrial adenocarcinoma cells. Proc Natl Acad Sci USA 93:6169-6174 (1996).
2. Burton JL, Wells M: Recent advances in the histopathology and molecular pathology of carcinoma of the endometrium. Histopathology 33:297-303 (1998).
3. Chen D, Gallie BL, Squire JA: Minimal regions of chromosomal imbalance in retinoblastoma detected by comparative genomic hybridization. Cancer Genet Cytogenet 129:57-63 (2001).
4. Chhieng DC, Ross JS, Ambros RA: bcl-2 expression and the development of endometrial carcinoma. Mod Pathol 9:402-406 (1996).
5. Cingoz S, Altungoz O, Canda T, Saydam S, Aksakoglu G, Sakizli M: DNA copy number changes detected by comparative genomic hybridization and their association with clinicopathologic parameters in breast tumors. Cancer Genet Cytogenet 145:108-114 (2003).
6. Creasman WT, Odicino F, Maisonneuve P, Beller U, Benedet JL, et al: Carcinoma of the corpus uteri. J Epidemiol Biostat 6:47-86 (2001).
7. Giatromanolaki A, Sivridis E, Koukourakis MI, Harris AL, Gatter KC: Bcl-2 and p53 expression in stage I endometrial carcinoma. Anticancer Res 18:3689-3693 (1998).
8. Hirasawa A, Aoki D, Inoue J, Imoto I, Susumu N, et al: Unfavorable prognostic factors associated with high frequency of microsatellite instability and comparative genomic hybridization analysis in endometrial cancer. Clin Cancer Res 9:5675-5682 (2003).
9. Hong H, Yang L, Stallcup MR: Hormone-independent transcriptional activation and coactivator binding by novel orphan nuclear receptor ERR3. J Biol Chem 274:22618-22626 (1999).
10. Jadoul P, Donnez J: Conservative treatment may be beneficial for young women with atypical endometrial hyperplasia or endometrial adenocarcinoma. Fertil Steril 80:1315-1324 (2003).
11. Kallioniemi OP, Kallioniemi A, Piper J, Isola J, Waldman FM, et al: Optimizing comparative genomic hybridization for analysis of DNA sequence copy number changes in solid tumors. Genes Chromosomes Cancer 10:231-243 (1994).
12. Kato H, Zhou Y, Asanoma K, Kondo H, Yoshikawa Y, et al: Suppressed tumorigenicity of human endometrial cancer cells by the restored expression of the DCC gene. Br J Cancer 82:459-466 (2000).
13. Kiechle M, Jacobsen A, Schwarz-Boeger U, Hedderich J, Pfisterer J, Arnold N: Comparative genomic hybridization detects genetic imbalances in primary ovarian carcinomas as correlated with grade of differentiation. Cancer 91:534-540 (2001).
14. Lax SF: Molecular genetic pathways in various types of endometrial carcinoma: from a phenotypical to a molecular-based classification. Virchows Arch 444:213-223 (2004).
15. Lutz W, Leon J, Eilers M: Contributions of Myc to tumorigenesis. Biochim Biophys Acta 1602:61-71 (2002).
16. Micci F, Teixeira MR, Haugom L, Kristensen G, Abeler VM, Heim S: Genomic aberrations in carcinomas of the uterine corpus. Genes Chromosomes Cancer 40:229-246 (2004).
17. Milatovich A, Heerema NA, Palmer CG: Cytogenetic studies of endometrial malignancies. Cancer Genet Cytogenet 46:41-53 (1990).
18. Miturski R, Semczuk A, Tomaszewski J, Jakowicki J: bcl-2 protein expression in endometrial carcinoma: the lack of correlation with p53. Cancer Lett 133:63-69 (1998).
19. Muresu R, Cossu A, Scarpa AM, Volpi EV, Rocca PC, et al: Numerical abnormalities of chromosomes 1 and 10 in endometrial adenocarcinoma: fluorescence in situ hybridization analysis of 23 archival paraffin-embedded samples. Cancer Genet Cytogenet 107:37-42 (1998).
20. Niederacher D, An HX, Cho YJ, Hantschmann P, Bender HG, Beckmann MW: Mutations and amplification of oncogenes in endometrial cancer. Oncology 56:59-65 (1999).
21. Nishimura T, Nishida N, Itoh T, Kuno M, Minata M, et al: Comprehensive allelotyping of well-differentiated human hepatocellular carcinoma with semiquantitative determination of chromosomal gain or loss. Genes Chromosomes Cancer 35:329-339 (2002).
22. Ozaki T, Schaefer KL, Wai D, Buerger H, Flege S, et al: Genetic imbalances revealed by comparative genomic hybridization in osteosarcomas. Int J Cancer 102:355-365 (2002).
23. Partheen K, Levan K, Osterberg L, Helou K, Horvath G: Analysis of cytogenetic alterations in stage III serous ovarian adenocarcinoma reveals a heterogeneous group regarding survival, surgical outcome, and substage. Genes Chromosomes Cancer 40:342-348 (2004).
24. Saito T, Nishimura M, Yamasaki H, Kudo R: Hypermethylation in promoter region of E-cadherin gene is associated with tumor dedifferention and myometrial invasion in endometrial carcinoma. Cancer 97:1002-1009 (2003).
25. Sakuragi N, Nishiya M, Ikeda K, Ohkouch T, Furth EE, et al: Decreased E-cadherin expression in endometrial carcinoma is associated with tumor dedifferentiation and deep myometrial invasion. Gynecol Oncol 53:183-189 (1994).
26. Sherman ME: Theories of endometrial carcinogenesis: a multidisciplinary approach. Mod Pathol 13:295-308 (2000).
27. Sonoda G, du Manoir S, Godwin AK, Bell DW, Liu Z, et al: Detection of DNA gains and losses in primary endometrial carcinomas by comparative genomic hybridization. Genes Chromosomes Cancer 18:115-125 (1997).
28. Soslow RA, Shen PU, Chung MH, Isacson C: Distinctive p53 and mdm2 immunohistochemical expression profiles suggest different pathogenetic pathways in poorly differentiated endometrial carcinoma. Int J Gynecol Pathol 17:129-134 (1998).
29. Spruck CH, Strohmaier H, Sangfelt O, Muller HM, Hubalek M, et al: hCDC4 gene mutations in endometrial cancer. Cancer Res 62:4535-4539 (2002).
30. Suehiro Y, Umayahara K, Ogata H, Numa F, Yamashita Y, et al: Genetic aberrations detected by comparative genomic hybridization predict outcome in patients with endometrioid carcinoma. Genes Chromosomes Cancer 29:75-82 (2000).
31. Suzuki A, Fukushige S, Nagase S, Ohuchi N, Satomi S, Horii A: Frequent gains on chromosome arms 1q and/or 8q in human endometrial cancer. Hum Genet 100:629-636 (1997).
32. Ward S, Harding B, Wilkins P, Harkness W, Hayward R, et al: Gain of 1q and loss of 22 are the most common changes detected by comparative genomic hybridisation in paediatric ependymoma. Genes Chromosomes Cancer 32:59-66 (2001).