Defective ribosomal protein gene expression alters transcription, translation, apoptosis, and oncogenic pathways in Diamond-Blackfan anemia

Stem Cells

Volumn 24, Issue 9, 2006, Pages 2034-2044

  Gazda, Hanna T ^a,b,c   Kho, Alvin T ^a,b,d   Sanoudou, Despina ^b,c,e   Zaucha, Jan M ^f   Kohane, Isaac S ^b,c,d   Sieff, Colin A ^a,b,c   Beggs, Alan H ^b,c  

^a DANA FARBER CANCER INSTITUTE   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d HARVARD UNIVERSITY   (United States)

^e BIOMEDICAL RESEARCH FOUNDATION   (Greece)

^f MEDICAL UNIVERSITY OF GDANSK   (Poland)

Author keywords

Apoptosis; Bone marrow failure; Cancer; Diamond Blackfan anemia; Global gene expression; Ribosomal protein genes

Indexed keywords

FAS ANTIGEN; PROTEIN MYB; PROTEIN RIBOSOMAL PROTEIN S19; RIBOSOME PROTEIN; UNCLASSIFIED DRUG;

ADULT; APOPTOSIS; ARTICLE; BLACKFAN DIAMOND ANEMIA; CANCER GENETICS; CARCINOGENESIS; CASE REPORT; CELL ISOLATION; CELL POPULATION; CONTROLLED STUDY; CORRELATION ANALYSIS; DOWN REGULATION; ERYTHROID PRECURSOR CELL; FEMALE; GENE; GENE CONTROL; GENE EXPRESSION; GENE MUTATION; GENETIC TRANSCRIPTION; GENOMICS; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; MALE; MICROARRAY ANALYSIS; MULTIPOTENT STEM CELL; ONCOGENE RAS; PROTEIN FOLDING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA TRANSLATION; TNFRSF10B GENE; VALIDATION STUDY;

ADULT; ANEMIA, DIAMOND-BLACKFAN; ANIMALS; APOPTOSIS; CASE-CONTROL STUDIES; CELL SEPARATION; ERYTHROID PROGENITOR CELLS; FEMALE; GENE EXPRESSION REGULATION; GENOME, HUMAN; HUMANS; MALE; MICE; MICROARRAY ANALYSIS; MUTATION; NEOPLASMS; PROTEIN BIOSYNTHESIS; PROTO-ONCOGENE PROTEINS C-MYB; REPRODUCIBILITY OF RESULTS; RIBOSOMAL PROTEINS; RNA, RIBOSOMAL, 18S; TRANSCRIPTION, GENETIC;

EID: 33748744175     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1634/stemcells.2005-0554     Document Type: Article

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