Oxcarbazepine Monotherapy in Children and Adolescents: A Single-Center Clinical Experience

Pediatric Neurology

Volumn 35, Issue 4, 2006, Pages 235-239

  Kothare, Sanjeev V ^a   Khurana, Divya S ^a   Mostofi, Navid ^a   Melvin, Joseph J ^a   Marks, Harold G ^a   Valencia, Ignacio ^a   Legido, Agustin ^a  

^a ST CHRISTOPHER'S HOSPITAL FOR CHILDREN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBAMAZEPINE; OXCARBAZEPINE;

ADOLESCENT; ADULT; AGGRESSION; ARTICLE; ATAXIA; CHILD; CONTROLLED STUDY; CORRELATION COEFFICIENT; DIPLOPIA; DISEASE FREE INTERVAL; DIZZINESS; DROWSINESS; DRUG EFFICACY; DRUG ERUPTION; DRUG SUBSTITUTION; DRUG TOLERABILITY; FEMALE; FOCAL EPILEPSY; HUMAN; HYPONATREMIA; INFANT; LEG CRAMP; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; MONOTHERAPY; MORBIDITY; PRIORITY JOURNAL; SEIZURE; SIDE EFFECT; STUDENT T TEST; TREATMENT DURATION; TREATMENT WITHDRAWAL;

ADOLESCENT; ANTICONVULSANTS; CARBAMAZEPINE; CHILD; CHILD, PRESCHOOL; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROENCEPHALOGRAPHY; EPILEPSIES, PARTIAL; FEMALE; HUMANS; INFANT; LONG-TERM CARE; MALE; RETROSPECTIVE STUDIES; TREATMENT OUTCOME;

EID: 33748710820     PISSN: 08878994     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pediatrneurol.2006.02.009     Document Type: Article

References (18)

1. Epilepsy and Seizure Statistics. Epilepsy Foundation. Available at: http://www.epilepsyfoundation.org/answerplace/statistics.cfm. Accessed August 29, 2005.
2. Reynolds E.H., and Shorvon S.D. Monotherapy or polytherapy for epilepsy?. Epilepsia 22 (1981) 1-10
3. Brodie M.J., and Kwan P. Staged approach to epilepsy management. Neurology 58 Suppl. 5 (2002) S2-S8
4. French J.A., Kanner A.M., Bautista J., et al. Efficacy and tolerability of the new antiepileptic drugs I: Treatment of new onset epilepsy: Report of the Therapeutics and Technology Assessment Subcommittee and Quality Standards Subcommittee of the American Academy of Neurology and the American Epilepsy Society. Neurology 62 (2004) 1252-1260
5. Bourgeois B.F., and D'Souza J. Long-term safety and tolerability of oxcarbazepine in children: A review of clinical experience. Epilepsy Behav 7 (2005) 375-382
6. Cukiert A., Sachdeo R., Ayala R., et al. A multicenter, rater-blind, randomized, age-stratified, parallel-group study comparing high- versus low-dose oxcarbazepine monotherapy in pediatric patients with inadequately controlled partial seizures. Epilepsia 45 Suppl. 7 (2004) 318
7. Gaily E., Granstrom M.L., and Liukkonen E. Oxcarbazepine in the treatment of early childhood epilepsy. J Child Neurol 12 (1997) 496-498
8. Guerreiro M.M., Vigonius U., Pohlmann H., et al. A double-blind controlled clinical trial of oxcarbazepine versus phenytoin in children and adolescents with epilepsy. Epilepsy Res 27 (1997) 205-213
9. Serdaroglu G., Kurul S., Tutuncuoglu S., Dirik E., and Sarioglu B. Oxcarbazepine in the treatment of childhood epilepsy. Pediatr Neurol 28 (2003) 37-41
10. Glauser T.A., Nigro M., Sachdeo R., et al., Oxcarbazepine Pediatric Study Group. Adjunctive therapy with oxcarbazepine in children with partial seizures. Neurology 54 (2000) 2237-2244
11. Piña-Garza J.E., Espinoza R., Nordli D., et al. Oxcarbazepine adjunctive therapy in infants and young children with partial seizures. Neurology 65 (2005) 1370-1375
12. Rey E., Bulteau C., Motte J., et al. Oxcarbazepine pharmacokinetics and tolerability in children with inadequately controlled epilepsy. J Clin Pharmacol 44 (2004) 1290-1300
13. Patsalos P.N., and Perucca E. Clinically important drug interactions in epilepsy: Interactions between antiepileptic drugs and other drugs. Lancet Neurol 2 (2003) 473-481
14. Patsalos P.N., and Perucca E. Clinically important drug interactions in epilepsy: General features and interactions between antiepileptic drugs. Lancet Neurol 2 (2003) 347-356
15. Van Amelsvoort T., Bakshi R., Devaux C.B., and Schwabe S. Hyponatremia associated with carbamazepine and oxcarbazepine therapy: A review. Epilepsia 35 (1994) 181-188
16. Friis M.L., Kristensen O., Boas J., et al. Therapeutic experiences with 947 epileptic out-patients in oxcarbazepine treatment. Acta Neurol Scand 87 (1993) 224-227
17. Holtmann M., Krause M., Opp J., Tokarzewski M., Korn-Merker E., and Boenigk H.E. Oxcarbazepine-induced hyponatremia and the regulation of serum sodium after replacing carbamazepine with oxcarbazepine in children. Neuropediatrics 33 (2002) 298-300
18. Novak P.H., Ekins-Daukes S., Simpson C.R., Milne R.M., Helms P., and McLay J.S. Acute drug prescribing to children on chronic antiepilepsy therapy and the potential for adverse drug interactions in primary care. Br J Clin Pharmacol 59 (2005) 712-717