Emergence of multidrug-resistant Gram-negative bacteria during selective decontamination of the digestive tract on an intensive care unit

Journal of Antimicrobial Chemotherapy

Volumn 58, Issue 4, 2006, Pages 853-856

  Al Naiemi, Nashwan ^a,b   Heddema, Edou R ^a   Bart, Aldert ^a   de Jonge, Evert ^a   Vandenbroucke Grauls, Christina M ^a,b   Savelkoul, Paul H M ^b   Duim, Birgitta ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

ESBLs; Intensive care; Resistance; SDD

Indexed keywords

AMOXICILLIN PLUS CLAVULANIC ACID; AMPHOTERICIN B; CEFEPIME; CEFOTAXIME; CEFOXITIN; CEFPODOXIME; CEFTAZIDIME; CEPHALOSPORIN DERIVATIVE; CIPROFLOXACIN; COLISTIN; EXTENDED SPECTRUM BETA LACTAMASE; GENTAMICIN; TOBRAMYCIN;

AMPLIFIED FRAGMENT LENGTH POLYMORPHISM; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIUM IDENTIFICATION; BACTERIUM ISOLATION; DRUG DOSE REGIMEN; EPIDEMIC; ESCHERICHIA COLI; GASTROINTESTINAL INFECTION; GENE IDENTIFICATION; GENE SEQUENCE; GENETIC CODE; GRAM NEGATIVE BACTERIUM; HUMAN; INTENSIVE CARE UNIT; KLEBSIELLA PNEUMONIAE; MINIMUM INHIBITORY CONCENTRATION; MULTIDRUG RESISTANCE; NETHERLANDS; NONHUMAN; PLASMID; POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SEQUENCE ANALYSIS;

ANTI-BACTERIAL AGENTS; BETA-LACTAMASES; DECONTAMINATION; DIGESTIVE SYSTEM; DRUG RESISTANCE, MULTIPLE, BACTERIAL; ESCHERICHIA COLI; GRAM-NEGATIVE BACTERIA; HUMANS; INTENSIVE CARE UNITS; KLEBSIELLA PNEUMONIAE; MICROBIAL SENSITIVITY TESTS; PLASMIDS; POLYMERASE CHAIN REACTION; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; SEQUENCE ANALYSIS, DNA;

EID: 33748702672     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkl316     Document Type: Article

References (11)

1. Husni RN, Goldstein LS, Arroliga AC et al. Risk factors for an outbreak of multi-drug-resistant Acinetobacter nosocomial pneumonia among intubated patients. Chest 1999; 115: 1378-82.
2. Chen HY, Yuan M, Ibrahim-Elmagboul IB et al. National survey of susceptibility to antimicrobials amongst clinical isolates of Pseudomonas aeruginosa. J Antimicrob Chemother 1995; 35: 521-34.
3. Stoutenbeek CP, van Saene HK, Miranda DR et al. The effect of selective decontamination of the digestive tract on colonisation and infection rate in multiple trauma patients. Intensive Care Med 1984; 10: 185-92.
4. Bonten MJ, Kullberg BJ, van Dalen R et al. Selective digestive decontamination in patients in intensive care. The Dutch Working Group on Antibiotic Policy. J Antimicrob Chemother 2000; 46: 351-62.
5. de Jonge E, Schultz MJ, Spanjaard L et al. Effects of selective decontamination of digestive tract on mortality and acquisition of resistant bacteria in intensive care: A randomised controlled trial. Lancet 2003; 362: 1011-6.
6. Livermore DM, Brown DF. Detection of beta-lactamase-mediated resistance. J Antimicrob Chemother 2001; 48 Suppl 1: 59-64.
7. Al Naiemi N, Duim B, Savelkoul PH et al. Widespread transfer of resistance genes between bacterial species in an intensive care unit: implications for hospital epidemiology. J Clin Microbiol 2005; 43: 4862-1.
8. van Saene JJ, van Saene HK, Stoutenbeek CP et al. Influence of faeces on the activity of antimicrobial agents used for decontamination of the alimentary canal. Scand J Infect Dis 1985; 17: 295-300.
9. de Jonge E. Effects of selective decontamination of digestive tract on mortality and antibiotic resistance in the intensive-care unit. Curr Opin Crit Care 2005; 11: 144-9.
10. Patterson JE. Antibiotic utilization: Is there an effect on antimicrobial resistance? Chest 2001; 119: 426S-30S.
11. Luiten EJ, Hop WC, Lange JF et al. Controlled clinical trial of selective decontamination for the treatment of severe acute pancreatitis. Ann Surg 1995; 222: 57-65.