Antimicrobial susceptibility and molecular determinants of quinolone resistance in Neisseria gonorrhoeae isolates from Shanghai

Journal of Antimicrobial Chemotherapy

Volumn 58, Issue 4, 2006, Pages 868-872

  Yang, Yang ^a   Liao, Mingmin ^b   Gu, Wei Ming ^a   Bell, Kelli ^b   Wu, Lei ^a   Eng, Nelson F ^b   Zhang, Chu Guang ^a   Chen, Yue ^c   Jolly, Ann M ^c   Dillon, Jo Anne R ^b,d  

^a Shanghai Skin Disease and STD Hospital   (China)

^b UNIVERSITY OF SASKATCHEWAN   (Canada)

^c UNIVERSITY OF OTTAWA   (Canada)

^d UNIVERSITY OF SASKATCHEWAN   (Canada)

Author keywords

Gonorrhoea; N. gonorrhoeae; Resistance mechanisms

Indexed keywords

ANTIINFECTIVE AGENT; CEFTRIAXONE; CEPHALOSPORIN; CIPROFLOXACIN; DNA TOPOISOMERASE (ATP HYDROLYSING) A; PENICILLIN G; PENICILLINASE; PROTEIN PARC; QUINOLINE DERIVED ANTIINFECTIVE AGENT; SPECTINOMYCIN; TETRACYCLINE;

ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL CHROMOSOME; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIUM IDENTIFICATION; BACTERIUM ISOLATE; CHINA; CHROMOSOME ANALYSIS; CONTROLLED STUDY; DRUG INDICATION; GENE MUTATION; GENETIC CODE; GONORRHEA; HUMAN; MALE; MINIMUM INHIBITORY CONCENTRATION; MUTATIONAL ANALYSIS; NEISSERIA GONORRHOEAE; NONHUMAN; NUCLEOTIDE SEQUENCE; PLASMID;

ANTI-INFECTIVE AGENTS; CHINA; CIPROFLOXACIN; DNA GYRASE; DNA TOPOISOMERASE IV; DRUG RESISTANCE, BACTERIAL; HUMANS; MALE; MICROBIAL SENSITIVITY TESTS; MUTATION; NEISSERIA GONORRHOEAE; QUINOLONES;

EID: 33748693298     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkl301     Document Type: Article

References (11)

1. Dillon JR, Pagotto F. Importance of drug resistance in gonococci: From mechanisms to monitoring. Curr Opin Infect Dis 1999; 12: 35-40.
2. The WHO Western Pacific Gonococccal Antimicrobial Surveillance Program. Surveillance of antibiotic resistance in Neisseria gonorrhoeae in the WHO Western Pacific Region, 2003. Commun Dis Intell 2005; 29: 62-4.
3. Knapp JS, Fox KK, Trees DL et al. Fluoroquinolone resistance in Neisseria gonorrhoeae. Emerg Infect Dis 1997; 3: 33-39.
4. Tompkins JR, Zenilman JM. Quinolone resistance in Neisseria gonorrhoeae. Curr Infect Dis Rep 2001; 3: 156-161.
5. Trees DL, Sandul AL, Whittington WL et al. Identification of novel mutation patterns in the parC gene of ciprofloxacin-resistant isolates of Neisseria gonorrhoeae. Antimicrob Agents Chemother 1998; 42: 2103-2105.
6. Belland RJ, Morrison SG, Ison C et al. Neisseria gonorrhoeae acquires mutations in analogous regions of gyrA and parC in fluoroquinolone-resistant isolates. Mol Microbiol 1994; 14: 371-80.
7. National Committee for Clinical Laboratory Standards. Performance Standards for Antimicrobial Susceptibility Testing: Twelfth Informational Supplement M100-S12. NCCLS, Villanova, PA, USA, 2002.
8. Ye S, Su X, Wang Q et al. Fifteen year monitoring of drug resistance of gonococci. Chinese J Human Sexuality 2004; 13: 1-3.
9. The WHO Western Pacific Surveillance Program. Surveillance of antibiotic resistance in Neisseria gonorrhoeae in the WHO Western Pacific Region, 2004. Commun Dis Intell 2006; 30: 129-32.
10. Giles JA, Falconio J, Yuenger JD et al. Quinolone resistance-determining region mutations and por type of Neisseria gonorrhoeae isolates: resistance surveillance and typing by molecular methodologies. J Infect Dis 2004; 189: 2085-93.
11. Trees DL, Sandul AL, Peto-Mesola V et al. Alterations within the quinolone resistance-determining regions of gyrA and parC of Neisseria gonorrhoeae isolated in the Far East and the United States. Int J Antimicrob Agents 1999; 12: 325-32.