Anxiolytic effect of noscapine in mice

Pharmacological Reports

Volumn 58, Issue 4, 2006, Pages 568-570

  Khodarahmi, Parvin ^a   Rostami, Parvin ^b   Rashidi, Armin ^c   Khodarahmi, Iman ^c  

^a ISLAMIC AZAD UNIVERSITY   (Iran)

^b KHARAZMI UNIVERSITY   (Iran)

^c TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Anxiety; Dark light model; Mice; Noscapine

Indexed keywords

NOSCAPINE;

ANALYTICAL PARAMETERS; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANXIETY DISORDER; ARTICLE; CONTROLLED STUDY; DRUG DOSE REGIMEN; DRUG EFFICACY; DRUG MEGADOSE; LIGHT DARK CYCLE; LOCOMOTION; MALE; MOUSE; MOUSE STRAIN; NONHUMAN; STATISTICAL SIGNIFICANCE; TIME; TRANQUILIZING ACTIVITY;

EID: 33748661277     PISSN: 22995684     EISSN: 22995684     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Barre JL, Plisnier H: Experimental study relating to the antitussive properties of narcotine-hydrochloride. UNODC-Bulletin on Narcotics, 1959, 3, 7-14.
2. Costall B, Jones BJ, Kelly ME, Naylor RJ, Tomkins DM: Exploration of mice in a black and white test box: validation as a model of anxiety. Pharmacol Biochem Behav, 1989, 32, 777-785.
3. Eddy NB, Friebel H, Hahn KJ, Halbach H: Codeine and its alternatives for pain and cough relief. Bull WHO, 1969, 40, 425-454.
4. Fernandez F, Misilmeri MA, Felger JC, Devine DP: Nociceptin/Orphanin FQ increases anxiety-related behavior and circulating levels of corticosterone during neophobic tests of anxiety. Neuropsychopharmacology, 2004, 29, 59-71.
5. Fuentes JA, Longo VG: An investigation on the central effects of harmine, harmaline and related β-carbolines. Neuropharmacology, 1971, 10, 15-23.
6. Gershon S, Lang WJ: A psychopharmacological study of some indole alkaloids. Arch Int Pharmacodyn, 1962, 135, 31-56.
7. Idanpaan-Heikkila JE, Jalonen K, Vartiainen A: Evaluation of the antitussive effect of noscapine and codeine on citric acid cough in guinea pigs. Acta Pharmacol Toxicol, 1967, 25, 333-338.
8. 3H]noscapine in guinea pig brain tissue. Eur J Pharmacol, 1988, 145, 195-203.
9. Keqyang Y, Yong K, Nagalakshmi K, Shanks J, Kapp JA, Tekmal RR, Petros J et al.: Opium alkaloid noscapine is an antitumor agent that arrests metaphase and induces apoptosis in dividing cells. Proc Natl Acad Sci USA, 1998, 95, 1601-1606.
10. 3H]noscapine binding sites in brain: relationship to indoleamines and the phosphoinositide and adenylyl cyclase messenger systems. Mol Phannacol, 1992, 42, 619-626.
11. National Research Council, Guide for the Care and Use of Laboratory Animals. Department of Health and Human Services, Washington, DC, NIH Publication No. 85-23, 1985.
12. Paul BD, Dreka C, Knight ES, Smith ML: Gas chromatographic/mass spectrometric detection of narcotine, papaverine, and thebaine in seeds of Papaver somniferum. Planta Med, 1996, 62, 544-547.
13. Sigg EB, Gyermek L, Hill RT, Yen H: Neuropharmacology of some harmine derivatives. Arch Int Pharmacodyn Ther, 1964, 149, 164-180.
14. Young R, Johnson DN: A fully automated light/dark apparatus useful for comparing anxiolytic agents. Pharmacol Biochem Behav, 1991, 40, 739-743.