Constructing the side-chain of the polyketide herbicide herboxidiene: A protocol for the synthesis of enantiomerically enriched C-11 to C-19 fragments

Journal of the Chemical Society - Perkin Transactions 1

Volumn , Issue 9, 1997, Pages 1261-1263

  Banwell, Martin G ^a   Bui, Chinh T ^a,b,c   Hockless, David C R ^a   Simpson, Gregory W ^c  

^a AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c CSIRO   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 33748648668     PISSN: 0300922X     EISSN: None     Source Type: Journal    
DOI: 10.1039/a701360d     Document Type: Article

References (16)

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2. Kocienski and co-workers have recently described a particularly elegant synthesis of (+)-herboxidiene A, a diastereoisomer of the natural product (see N. D. Smith, P. J. Kocienski and S. D. A. Street, Synthesis, 1996, 652).
3. Workers at Sandoz Agro AG (Basel) and the University of Geneva have recently re-isolated herboxidiene and, using a combination of X-ray analysis, degradation and asymmetric synthesis of appropriate fragments have determined the relative and absolute configuration of the natural product (Dr A. J. F. Edmunds, personal communication to M. G. B.). However, at the time of writing, details of the full structure of herboxidiene are not available.
4. M. G. Banwell, C. T. Bui, G. W. Simpson and K. G. Watson, Chent. Commun., 1996, 723.
5. M. G. Banwell, C. T. Bui, G. W. Simpson and K. G. Watson, J. Chem. Soc., Perkin Trans. 1, to be submitted.
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