Prevalence and clinical features of Clostridium difficile-associated diarrhea in a tertiary hospital in northern Taiwan

Journal of Microbiology, Immunology and Infection

Volumn 39, Issue 3, 2006, Pages 242-248

  Hsu, Meng Shiuan ^a   Wang, Jann Tay ^a   Huang, Wen Kuei ^b   Liu, Yung Ching ^b,c   Chang, Shan Chwen ^a,d  

^a NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^b KAOHSIUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^c NATIONAL YANG MING UNIVERSITY   (Taiwan)

^d NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

Antibacterial agents; Clostridium difficile; Diarrhea; Prevalence; Risk factors; Taiwan

Indexed keywords

AMPHOTERICIN B; ANTIBIOTIC AGENT; ANTIFUNGAL AGENT; BACTERIAL TOXIN; CARBAPENEM; CEFEPIME; CEFOTIAM; CEFPIROME; CEFTRIAXONE; CEFUROXIME; CEPHALOSPORIN DERIVATIVE; CIPROFLOXACIN; CISPLATIN; FLUCONAZOLE; GEFITINIB; IMIPENEM; MEROPENEM; METRONIDAZOLE; NAVELBINE; PENICILLIN DERIVATIVE; PIPERACILLIN PLUS TAZOBACTAM; SULTAMICILLIN; THALIDOMIDE; TIMENTIN; VANCOMYCIN;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL FEATURE; CLOSTRIDIUM DIFFICILE; CONTROLLED STUDY; FECES ANALYSIS; HUMAN; INFECTIOUS DIARRHEA; PREVALENCE; RISK FACTOR; TAIWAN; TERTIARY HEALTH CARE;

ADULT; AGED; AGED, 80 AND OVER; ANTI-BACTERIAL AGENTS; ANTIFUNGAL AGENTS; BACTERIAL PROTEINS; BACTERIAL TOXINS; CLOSTRIDIUM DIFFICILE; DIARRHEA; ENTEROCOLITIS, PSEUDOMEMBRANOUS; ENTEROTOXINS; FECES; FEMALE; HUMANS; MALE; PREVALENCE; RISK FACTORS; TAIWAN;

EID: 33748639961     PISSN: 16841182     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Mylonakis E, Ryan ET, Calderwood SB. Clostridium difficile-associated diarrhea. Arch Intern Med 2001;161:525-33.
2. Hurley BW, Nguyen CC. The spectrum of pseudomembranous enterocolitis and antibiotic-associated diarrhea. Arch Intern Med 2002;162:2177-84.
3. Bartlett JG. Antibiotic-associated diarrhea. Clin Infect Dis 1992; 15:573-81.
4. Bartlett JG. Clinical practice. Antibiotic-associated diarrhea. N Engl J Med 2002;46:334-9.
5. Anand A, Glatt AE. Clostridium difficile infection associated with antineoplastic chemotherapy: a review. Clin Infect Dis 1993;17:109-13.
6. Sharma AK, Holder FE. Clostridium difficile diarrhea after use of tacrolimus following renal transplantation. Clin Infect Dis 1998;27:1540-1.
7. Anand A, Bashey B, Mir T, Glatt AE. Epidemiology, clinical manifestations, and outcome of Clostridium difficile-associated diarrhea. Am J Gastroenterol 1994;89:519-23.
8. Allen SD, Emery CL, Lyerly DM. Clostridium. In: Murray PR, Baron EJ, Jorgensen JH, Pfaller MA, Yolken RH, eds. Manual of clinical microbiology. 8th ed. Washington, D. C.: American Society of Microbiology Press; 2003:835-56.
9. Brown E, Talbot GH, Axelrod P, Provencher M, Hoegg C. Risk factors for Clostridium difficile toxin-associated diarrhea. Infect Control Hosp Epidemiol 1990;11:283-90.
10. Pierce PF Jr, Wilson R, Silva J Jr, Garagusi VF, Rifkin GD, Fekety R, et al. Antibiotic-associated pseudomembranous colitis: an epidemiologic investigation of a cluster of cases. J Infect Dis 1982;145:269-74.
11. Karlstrom O, Fryklund B, Tullus K, Burman LG. A prospective nationwide study of Clostridium difficile-associated diarrhea in Sweden. The Swedish C. difficile Study Group. Clin Infect Dis 1998;26:141-5.
12. Kyne L, Hamel MB, Polavaram R, Kelly CP. Health care costs and mortality associated with nosocomial diarrhea due to Clostridium difficile. Clin Infect Dis 2002;34:346-53.
13. Neu HC, Prince A, Neu CO, Garvey GJ. Incidence of diarrhea and colitis associated with clindamycin therapy. J Infect Dis 1977;135(Suppl):S120-5.
14. Gurwith MJ, Rabin HR, Love K. Diarrhea associated with clindamycin and ampicillin therapy: preliminary results of a cooperative study. J Infect Dis 1977;135(Suppl):S104-10.
15. Swartzberg JE, Maresca RM, Remington JS. Gastrointestinal side effects associated with clindamycin. 1,000 consecutive patients. Arch Intern Med 1976;136:876-9.
16. Gorschluter M, Glasmacher A, Hahn C, Schakowski F, Ziske C, Molitor E, et al. Clostridium difficile infection in patients with neutropenia. Clin Infect Dis 2001;33:786-91.
17. Yamazawa K, Kanno H, Seki K, Kazuta T, Matsui H, Sekiya S. Life-threatening Clostridium difficile-associated diarrhea induced by paclitaxel-carboplatin combination chemotherapy. Acta Obstet Gynecol Scand 2001;80:768-9.
18. Casciato DA, Lowitz BB. Cancer chemotherapeutic agents. In: Casciato DA, Lowitz BB, eds. Manual of Clinical Oncology. 4th ed. New York: Lippincott Williams and Wilkins Press; 2000: 48-95.
19. Moncrief JS, Zheng L, Neville LM, Lyerly DM. Genetic characterization of toxin-A-negative, toxin B-positive Clostridium difficile isolates by PCR. J Clin Microbiol 2000; 38:3072-5.
20. + strain of Clostridium difficile. J Clin Microbiol 2000;38:1696-7.