Predictors of recurrence in patients with T2 and early T3, N0 adenocarcinoma of the rectum treated by surgery alone

Journal of Clinical Oncology

Volumn 24, Issue 25, 2006, Pages 4078-4084

  Nissan, Aviram ^a   Stojadinovic, Alexander ^a   Shia, Jinru ^a   Hoos, Axel ^a   Guillem, Jose G ^a   Klimstra, David ^a   Cohen, Alfred M ^a   Minsky, Bruce D ^a   Paty, Philip B ^a   Wong, W Douglas ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOEMBRYONIC ANTIGEN;

ADULT; AGED; ARTICLE; CANCER INVASION; CANCER PATIENT; CANCER RECURRENCE; CANCER SURVIVAL; DISEASE FREE SURVIVAL; FEMALE; FOLLOW UP; HUMAN; MAJOR CLINICAL STUDY; MALE; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; RECTUM CARCINOMA; TREATMENT OUTCOME; ADENOCARCINOMA; BLOOD; CANCER STAGING; IMMUNOLOGY; LYMPH NODE METASTASIS; MIDDLE AGED; PATHOLOGY; PREDICTION AND FORECASTING; PROSPECTIVE STUDY; RECTUM TUMOR; RISK ASSESSMENT; RISK FACTOR; SURVIVAL; TUMOR RECURRENCE;

ADENOCARCINOMA; ADULT; AGED; AGED, 80 AND OVER; CARCINOEMBRYONIC ANTIGEN; FEMALE; FOLLOW-UP STUDIES; HUMANS; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; NEOPLASM INVASIVENESS; NEOPLASM RECURRENCE, LOCAL; NEOPLASM STAGING; PREDICTIVE VALUE OF TESTS; PROSPECTIVE STUDIES; RECTAL NEOPLASMS; RISK ASSESSMENT; RISK FACTORS; SURVIVAL ANALYSIS;

EID: 33748636426     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.2006.06.2968     Document Type: Article

References (43)

1. Cedermark B, Johansson H, Rutqvist LE, et al: The Stockholm I trial of preoperative short term radiotherapy in operable rectal carcinoma: A prospective randomized trial - Stockholm Colorectal Cancer Study Group. Cancer 75:2269-2275, 1995
2. Pahlman L, Glimelius B: Pre- or postoperative radiotherapy in rectal and rectosigmoid carcinoma: Report from a randomized multicenter trial. Ann Surg 211:187-195, 1990
3. Improved survival with preoperative radiotherapy in resectable rectal cancer: Swedish Rectal Cancer Trial. N Engl J Med 336:980-987, 1997
4. Kapiteijn E, Marijnen CA, Nagtegaal ID, et al: Dutch Colorectal Cancer Group: Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer. N Engl J Med 345:638-646, 2001
5. Sauer R, Becker H, Hohenberger W, et al: German Rectal Cancer Study Group: Preoperative versus postoperative chemoradiotherapy for rectal cancer. N Engl J Med 351:1731-1740, 2004
6. Heald RJ, Ryall RD: Recurrence and survival after total mesorectal excision for rectal cancer. Lancet 1:1479-1482, 1986
7. Kapiteijn E, van De Velde CJ: European trials with total mesorectal excision. Semin Surg Oncol 19:350-357, 2000
8. NIH Consensus Conference: Adjuvant therapy for patients with colon and rectal cancer. JAMA 264:1444-1450, 1990
9. Gastrointestinal Tumor Study Group: Prolongation of the disease-free interval in surgically treated rectal carcinoma. N Engl J Med 312:1465-1472, 1985
10. Krook JE, Moertel CG, Gunderson LL, et al: Effective surgical adjuvant therapy for high-risk rectal carcinoma. N Engl J Med 324:709-715, 1991
11. Simunovic M, Sexton R, Rempel E, et al: Optimal preoperative assessment and surgery for rectal cancer may greatly limit the need for radiotherapy. Br J Surg 90:999-1003, 2003
12. Enker WE, Thaler HT, Cranor ML, et al: Total mesorectal excision in the operative treatment of carcinoma of the rectum. J Am Coll Surg 181:335-346, 1995
13. Harrison LE, Guillem JG, Paty P, et al: Preoperative carcinoembryonic antigen predicts outcomes in node-negative colon cancer patients: A multivariate analysis of 572 patients. J Am Coll Surg 185:55-59, 1997
14. Blumberg D, Paty PB, Picon AI, et al: Stage 1 rectal cancer: Identification of high-risk patients. J Am Coll Surg 186:574-579, 1998
15. Talbot IC, Ritchie S, Leighton M, et al: Invasion of veins by carcinoma of rectum: Method of detection, histological features and significance. Histopathology 5:141-163, 1981
16. Talbot IC, Ritchie S, Leighton MH, et al: The clinical significance of invasion of veins by rectal cancer. Br J Surg 67:439-442, 1980
17. Green JB, Timmcke AE, Mitchell WT, et al: Mucinous carcinoma: Just another colon cancer? Dis Colon Rectum 36:49-54, 1993
18. Nissan A, Guillem JG, Paty PB, et al: Signet-ring cell carcinoma of the colon and rectum: A matched control study. Dis Colon Rectum 42:1176-1180, 1999
19. Compton CC, Fielding LP, Burgart LJ, et al: Prognostic factors in colorectal cancer: College of American Pathologists Consensus Statement 1999. Arch Pathol Lab Med 124:979-994, 2000
20. Buglioni S, D'Agnano I, Cosimelli M, et al: Evaluation of multiple bio-pathological factors in colorectal adenocarcinomas: Independent prognostic role of p53 and bcl-2. Int J Cancer 84:545-552, 1999
21. Ahnen DJ, Feigl P, Quan G, et al: Ki-ras mutation and p53 overexpression predict the clinical behavior of colorectal cancer: A Southwest Oncology Group study. Cancer Res 58:1149-1158, 1998
22. Cohen AM: Total rectal resection. Ann Surg Oncol 7:85-86, 2000
23. Kaplan E, Meier P: Nonparametric estimation from incomplete observations. J Am Statist Assoc 53:457-481, 1958
24. Peto R, Peto J: Asymptotically efficient rank invariant procedures. J R Stat Soc A 135:185-207, 1972
25. Bartelink H, Roelofsen F, Eschwege F, et al: Concomitant radiotherapy and chemotherapy is superior to radiotherapy alone in the treatment of locally advanced anal cancer: Results of a phase III randomized trial of the European Organization for Research and Treatment of Cancer Radiotherapy and Gastrointestinal Cooperative Groups. J Clin Oncol 15:2040-2049, 1997
26. Wolmark N, Wieand HS, Hyams DM, et al: Randomized trial of postoperative adjuvant chemotherapy with or without radiotherapy for carcinoma of the rectum: National Surgical Adjuvant Breast and Bowel Project Protocol R-02. J Natl Cancer Inst 92:388-396, 2000
27. Fisher B, Wolmark N, Rockette H, et al: Postoperative adjuvant chemotherapy or radiation therapy for rectal cancer: Results from NSABP protocol R-01. J Natl Cancer Inst 80:21-29, 1988
28. Gunderson LL, Sargent DJ, Tepper JE, et al: Impact of T and N stage and treatment on survival and relapse in adjuvant rectal cancer: A pooled analysis. J Clin Oncol 22:785-796, 2004
29. Bosset JF, Calais G, Mineur L, et al: Preoperative radiation (Preop RT) in rectal cancer: Effect and timing of additional chemotherapy (CT) 5-year results of the EORTC 22921 trial. J Clin Oncol 24:247s, 2005 (suppl; abstr 3505)
30. Wanebo HJ, Rao B, Pinsky CM, et al: Preoperative carcinoembryonic antigen level as a prognostic indicator in colorectal cancer. N Engl J Med 299:448-451, 1978
31. Davey P, Arnott SJ, Sturgeon CM: Carcinoembryonic antigen as a prognostic indicator in the radiotherapeutic management of rectal cancer. Eur J Surg Oncol 13:17-20, 1987
32. Wolmark N, Fisher B, Wieand HS, et al: The prognostic significance of preoperative carcinoembryonic antigen levels in colorectal cancer: Results from NSABP (National Surgical Adjuvant Breast and Bowel Project) clinical trials. Ann Surg 199:375-382, 1984
33. Willett CG, Compton CC, Shellito PC, et al: Selection factors for local excision or abdominoperineal resection of early stage rectal cancer. Cancer 73:2716-2720, 1994
34. Minsky BD, Rich T, Recht A, et al: Selection criteria for local excision with or without adjuvant radiation therapy for rectal cancer. Cancer 63:1421-1429, 1989
35. Minsky BD, Enker WE, Cohen AM, et al: Clinicopathologic features in rectal cancer treated by local excision and postoperative radiation therapy. Radiat Med 13:235-241, 1995
36. Geraghty JM, Williams CB, Talbot IC: Malignant colorectal polyps: Venous invasion and successful treatment by endoscopic polypectomy. Gut 32:774-778, 1991
37. Minsky BD, Mies C, Recht A, et al: Resectable adenocarcinoma of the rectosigmoid and rectum: II. The influence of blood vessel invasion. Cancer 61:1417-1424, 1988
38. Ouchi K, Sugawara T, Ono H, et al: Histologic features and clinical significance of venous invasion in colorectal carcinoma with hepatic metastasis. Cancer 78:2313-2317, 1996
39. Willett CG, Badizadegan K, Ancukiewicz M, et al: Prognostic factors in stage T3N0 rectal cancer: Do all patients require postoperative pelvic irradiation and chemotherapy? Dis Colon Rectum 42:167-173, 1999
40. Willett CG, Lewandrowski K, Donnelly S, et al: Are there patients with stage I rectal carcinoma at risk for failure after abdominoperineal resection? Cancer 69:1651-1655, 1992
41. Jessup JM, Loda M: Prognostic markers in rectal carcinoma. Semin Surg Oncol 15:131-140, 1998
42. Jessup JM, Loda M, Bleday R: Clinical and molecular prognostic factors in sphincter-preserving surgery for rectal cancer. Semin Radiat Oncol 8:54-69, 1998
43. Freedman LS, Macaskill P, Smith AN: Multivariate analysis of prognostic factors for operable rectal cancer. Lancet 2:733-736, 1984