A new adjacent bis-tetrahydrofuran annonaceous acetogenin from the seeds of Uvaria chamae

Planta Medica

Volumn 72, Issue 10, 2006, Pages 938-940

  Fall, Djibril ^a,b   Pimentel, Lorena ^a   Champy, Pierre ^a   Gleye, Christophe ^a   Laurens, Alain ^a   Hocquemiller, Reynald ^a  

^a UNIVERSITÉ PARIS SACLAY   (France)

^b UNIVERSITÉ CHEIKH ANTA DIOP   (Senegal)

Author keywords

[No Author keywords available]

Indexed keywords

ACETOGENIN; CHAMUVARININ; DEACETYLUVARICIN; DIEPORETICANIN 1; DIEPORETICANIN 2; DIEPOXYROLLIN; SQUAMOCIN; TETRAHYDROFURAN DERIVATIVE; TRIPOXYROLLIN; UNCLASSIFIED DRUG;

ARTICLE; DRUG ISOLATION; PLANT SEED; UVARIA;

ANNONACEAE; UVARIA CHAMAE;

EID: 33748630487     PISSN: 00320943     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2006-941542     Document Type: Article

References (17)

1. Bermejo A, Figadère B, Zafra-Polo M-C, Barrachina I, Estornell E, Cortes D. Acetogenins from Annonaceae: Recent progress in isolation, synthesis and mechanisms of action. Nat Prod Rep 2005; 22: 269-303
2. Derbré S, Roué G, Poupon E, Susin SA, Hocquemiller R. Annonaceous acetogenins: The hydroxyl groups and THF rings are crucial structural elements for targeting the mitochondria, demonstration with the synthesis of fluorescent squamocin analogues. Chem Biol Chem 2005; 6: 1-4
3. Champy P, Höglinger GU, Féger J, Gleye C, Hocquemiller R, Laurens A et al. Annonacin, a lipophilic inhibitor of mitochondrial complex I, induces nigral and striatal neurodegeneration in rats: Possible relevance for atypical parkinsonism in Guadeloupe. J Neurochem 2004; 88: 63-9
4. Champy P, Melot A, Guérineau V, Gleye C, Fall D, Höglinger GU et al. Quantification of acetogenins in Annona muricata linked to atypical parkinsonism in Guadeloupe. Mov Disord 2005; 20: 1629-33
5. Fall D, Gleye C, Franck C, Laurens A, Hocquemiller R. cis-Bullatencin, a linear acetogenin from roots of Uvario chamae. Nat Prod Lett 2002; 16: 315-21
6. Fall D, Duval RA, Gleye C, Laurens A, Hocquemiller R. Chamuvarinin, an acetogenin bearing a tetrahydropyran ring from the roots of Uvaria chamae. J Nat Prod 2004; 67: 1041-3
7. Fujimoto Y, Eguchi T, Kakinuma K, Ikekawa N, Sahai M, Gupta YK. Squamocin, a new cytotoxic bis-tetrahydrofuran containing acetogenin from Annona squamosa. Chem Pharm Bull 1988; 36: 4802-6
8. Jolad SD, Hoffmann JJ, Cole JR, Barry CE, Bates RB, Linz GS et al. Desacetyluvaricin from Uvaria acuminata, configuration of uvaricin at C-36. J Nat Prod 1985; 48: 644-5
9. Sahpaz S, Figadère B, Saez J, Hocquemiller R, Cavé A, Cortes D. Tripoxyrollin, a new epoxyacetogenin from the seeds of Rollinia membranacea. Nat Prod Lett 1993; 2: 301-8
10. Sahpaz S, Hocquemiller R, Cavé A, Saez J, Cortes D. Diepoxyrollin and diepomuricanin B, two new diepoxyacetogenins from Rollinia membranacea seeds. J Nat Prod 1997; 60: 199-201
11. Vu Thi Tam, Phan Quan Chi Hieu, Chappe B, Roblot F, Laprévote O, Figadère B et al. Four new acetogenins from the seeds of Annona reticulata. Nat Prod Lett 1994; 4: 255-62
12. Latypov S, Franck X, Jullian J-C, Hocquemiller R, Figadère B. NMR determination of absolute configuration of butenolides of annonaceous type. Chem Eur J 2002; 8: 5662-6
13. Fujimoto Y, Murasaki C, Shimada H, Nishioka S, Kakinuma K, Singh S et al. Annonaceous acetogenins from the seeds of Annona squamosa. Non-adjacent bis-tetrahydrofuranic acetogenins. Chem Pharm Bull 1994; 42: 1175-84
14. Chen Y, Chen YR, Yu DQ. Six acetogenins from Uvaria tonkinesis. Phytochemistry 1996; 43: 793-801
15. Qin Y, Pan X, Chen R, Yu D. New annonaceous acetogenins from Uvaria boniana. Yao Xue Xue Bao (Acta Pharm Sin) 1996; 31: 381-6
16. Sinz A, Matusch R, Kämpchen T, Fiedler W, Schmidt J, Santisuk T et al. Novel acetogenins from the leaves of Dasymaschalon sootepense. Helv Chim Acta 1998; 81: 1608-15
17. Fleury C, Cotte J, Quéro A-M. Evaluation de la cytotoxicité d'un antiseptique par une microméthode photométrique. Path Biol 1984; 32: 628-30