Abnormal intestinal permeability in primary biliary cirrhosis

Digestive Diseases and Sciences

Volumn 51, Issue 9, 2006, Pages 1607-1613

  Feld, Jordan J ^a,b,c   Meddings, Jonathan ^a,b   Heathcote, E Jenny ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF CALGARY   (Canada)

^c NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

Intestinal permeability; Molecular mimicry; Portal hypertension; Primary biliary cirrhosis

Indexed keywords

BACTERIAL PROTEIN; LACTULOSE; MANNITOL; MITOCHONDRION ANTIBODY; SUCROSE;

ARTICLE; CONTROLLED STUDY; HEPATITIS C; HUMAN; INTESTINE MUCOSA PERMEABILITY; LIVER DISEASE; MAJOR CLINICAL STUDY; PORTAL HYPERTENSION; PRIMARY BILIARY CIRRHOSIS; PRIORITY JOURNAL; URINARY EXCRETION;

ADULT; AGED; COHORT STUDIES; FEMALE; HUMANS; INTESTINAL ABSORPTION; INTESTINAL MUCOSA; INTESTINES; LACTULOSE; LIVER CIRRHOSIS, BILIARY; LIVER FUNCTION TESTS; MALE; MIDDLE AGED; PERMEABILITY; SEVERITY OF ILLNESS INDEX; SUCROSE;

EID: 33748616586     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10620-006-9544-z     Document Type: Article

References (46)

1. Lindenborn-Fotinos J, Baum H, Berg PA (1985) Mitochondrial antibodies in primary biliary cirrhosis: further characterization of the M2 antigen by immunoblotting revealing species and nonspecies specific determinants. Hepatology 5:763-769
2. Frazer IH, Mackay IR, Jordan TW, Whittingham S, Marzuki S (1985) Reactivity of antimitochondrial antibodies in primary biliary cirrhosis: definition of two novel mitochondrial polypeptide auto-antigens. J Immunol 135:1739-1745
3. Fussey S, Lundsay J, Fuller C, Perham R, Dale S, James O, Bassendine M, Yeaman S (1991) Autoantibodies in primary biliary cirrhosis: analysis of reactivity against eukaryotic and prokaryotic 2-oxo acid dehydrogenase complexes. Hepatology 13:467-474
4. Yeaman S, Fussy S, Danner D, James O, Mutimer D, Bassendine M (1988) Primary biliary cirrhosis: identification of two major M2 mitochondrial autoantigens. Lancet 1:1067-1070
5. Fussey S, Guest J, James O, Bassendine M, Yeaman S (1988) Identification and analysis of major M2 autoantigens in primary biliary cirrhosis. Proc Natl Acad Sci USA 85:8654-8658
6. Van de Water J, Frageau D, Davis P, Ansari A, Danner D, Leung P, Coppel R (1988) Autoantibodies of primary biliary cirrhosis (PBC) recognize dihydrolipoamide acetyltransferase and inhibit enzyme function. J Immunol 141:2321-2324
7. Surh C, Danner D, Ahmed A, Coppel R, Mackay I, Dickson E, Gershwin M (1989) Reactivity of primary biliary cirrhosis sera with a human fetal liver cDNA clone of branched-chain α-keto acid dehydrogenase dihydrolipoamide acetyltransferase, the 52 kD mitochondrial autoantigen. Hepatology 9:63-68
8. Fussey S, Bassendine M, Fittes D, Turner I, James O, Yeaman S (1989) The E1 α and β subunits of the pyruvate dehydrogenase complex are M2"d" and M2"e" autoantigens in primary biliary cirrhosis. Clin Sci 77:365-368
9. Fregeau D, Roche T, Davis P Coppel R, Gershwin M (1990) Primary biliary cirrhosis: inhibition of pyruvate dehydrogenase complex activity by autoantibodies specific for E1α, a non-lipoic acid containing mitochondrial enzyme. J Immunol 144:1671-1676
10. Fussey S, Ali S, Guest J, James O, Bassendine M, Yeaman S (1990) Reactivity of primary biliary cirrhosis sera with Escherichia coli dihydrolipoamide acetyltransferase (E2p): characterization of the main immunogenic region. Proc Natl Acad Sci USA 87:3987-3991
11. Stemerowicz R, Moller B, Rodloff A, et al. (1988) Are antimitochondrial antibodies in primary biliary cirrhosis induced by R(rough)-mutants of Enterobacteriaceae? Lancet 2:1167-1170
12. Hopf U, Stemerowicz R, Rodloff A, Calanos C, Moller B, Hartmut L, Freudenberg M, Huhn D (1989) Relation between Escherichia coli R(rough)-forms in gut, lipid A in liver, and primary biliary cirrhosis. Lancet 2:1419-1421
13. Burroughs A, Butler K, Brown D, Drumfitt W, Hamilton-Miller J, Baum H (1984) Bacteriuria and primary biliary cirrhosis. Gut 25:133-137
14. Morreale M, Tsirigotis M, Hughes MD, Brumfitt W, McIntyre N, Burroughs AK (1989) Significant bacteriuria has prognostic significance in primary biliary cirrhosis. J Hepatol 9(2):149-158
15. Kaplan M (1996) Primary biliary cirrhosis. N Engl J Med 21:1570-1580
16. Niveloni, Dezi R, Pedreira S, Podesta A, Cabanne A, Vazquez H, Sugai E, Smecuol E, Doldan E, Valero J, Kogan Z, Boerr L, Maurino E, Terg R, Bai J (1998) Gluten sensitivity in patients with primary biliary cirrhosis. Am J Gastroenterol 93:404-408
17. Olsen R, Kagevi Y, Rydberd L (1982) On the concurrence of primary biliary cirrhosis and intestinal villous atrophy. Scand J Gastroenerol 17:625-628
18. Primignani M, Carpinelli L, Preatoni P, et al. (2000) Natural history of portal hypertensive gastropathy in patients with liver cirrhosis. The New Italian Endoscopic Club for the study and treatment of esophageal varices (NIEC). Gastroenterology 119:181-187
19. Smecuol E, Bai JC, Vazquez H, Kogan Z, Cabanne A, Niveloni S, Pedreira S, Boerr L, Maurino E, Meddings J (1997) Gastrointestinal permeability in celiac disease. Gastroenterology 112:1129-1136
20. Bjarnason I, MacPherson A, Hollander D (1995) Intestinal permeability: an overview. Gastroenterology 108(5):1566-1581
21. Vazquez H, Sugai E, Pedreira S, Katz S, Litwin N, De Rosa S, Ruiz J, Soifer G, Kogan Z Boerr L, Bai JC (1995) Screening for asymptomatic celiac sprue in families. J Clin Gastroentorol 21:130-133
22. Budillon G, Parrilli G, Pacella M, Cuomo R, Menzies IS (1985) Investigation of intestine and liver function in cirrhosis using combined sugar oral loads. J Hepatol 1:513-524
23. Romiti A, Merli M, Martoarano M, Parrilli G, Martino F, Riggio O, Truscelli A, Capocaccia L, Budillon G (1990) Malabsorption and nutritional abnormalities in patients with liver cirrhosis. Ital J Gastroenterol 22:118-123
24. Taylor RM, Bjarnason I, Cheeseman P, Davenport M, Baker AJ, Mieli-Vergani G, Dhawan A (2002) Intestinal permeability and absorptive capacity in children with portal hypertension. Scand J Gastroenterol 37:807-811
25. Giofre MR, Meduri G, Pallio S, Calandra S, Magnano A, Niceforo D, Cinquegrani M, di Leo V, Mazzon E, Sturniolo GC, Longo G, Fries W (2000) Gastric permeability to sucrose is increased in portal hypertensive gastropathy. Eur J Gastro 12:529-539
26. De Leo V, Venturi C, Baragiotta A, Martines D, Floreani A (2003) Gastroduodenal and intestinal permeability in primary biliary cirrhosis. Eur J Gastroenterol Hepatol 15:967-973
27. Welsh F, Ramsden C, MacLennan K, Sheridan M, Barclay G, Guillou P, Reynolds J (1998) Increased intestinal permeability and altered mucosal immunity in cholestatic jaundice. Ann Surg 227:205-212
28. Smecuol E, Bai JC, Sugai E, Vazquez H, Niveloni S, Pedreira S, Maurino E, Meddings J (2001) Acute gastrointestinal permeability responses to different non-steroidal anti-inflammatory drugs. Gut 49:650-655
29. Keshavarzian A, Fields J, Vaeth J, Holmes E (1994) The differing effects of acute and chronic alcohol on gastric and intestinal permeability. Am J Gastroenterol 89:2205-2211
30. Fasano A, Budillon G, Guandalini S, Cuomo R, Parrilli G, Cangiotti AM, Morroni M, Rubino A (1990) Bile acids reversible effecs on small intestinal permeability. An in vitro study in the rabbi. Dig Dis Sci 35:801-808
31. Suenaert P, Bulteel V, Den Hond E, Hiele M, Peeters M, Monsuur F, Ghoos Y, Rutgeerts P (2000) The effects of smoking and indomethacin on small intestinal permeability. Aliment Pharmacol Ther 14:819-822
32. 14C-mannitol methods for intestinal permeability. Scand J Gastroenterol 32:805-812
33. Fukuda Y, Bamba H, Okui M, Tamura K, Tanida N, Satomi M, Shimoyama T, Nishigami T (2001) Helicobacter pylori infection increases mucosal permeability of the stomach and intestine. Digestion 63(Suppl 1):93-96
34. Spinzi G, Pellicano R, Minoli G, Terreni N, Cutufia MA, Fagoonee S, Rizzetto M, Ponzetto A (2001) Helicobacter pylori seroprevalence in hepatitis C virus positive patients with cirrhosis. The Como cross-sectional study. Panminerva Med 43:85-87
35. Dohmen K, Shigematsu H, Miyamoto Y, Yamasaki F, Irie K, Ishibashi H (2002) Atrophic corpus gastritis and Helicobacter pylori infection in primary biliary cirrhosis. Dig Dis Sci 47:162-169
36. Floreani A, Biagini MR, Zappala F, Farinati F, Plebani M, Rugge M, Surrenti C, Naccarato R (1997) Chronic atrophic gastritis and Helicobacter pylori infection in primary biliary cirrhosis: a cross-sectional study with matching. Ital J Gastroenterol Hepatol 29:13-17
37. Yuhan R, Koutsouris A, Savkovic SD, Hecht G (1997) Enteropathogenic Escherichia coli-induced myosin light chain phosphorylation alters intestinal epithelial permeability. Gastroenterology 113:1873-1882
38. Kennedy RJ, Kirk SJ, Gardiner KR (2002) Mucosal barrier function and the commensal flora. Gut 50:441-442
39. Ma TY, Hollander D, Dadufalza V, Krugliak P (1992) Effect of ageing and caloric restriction on intestinal permeability. Exp Gerontol 27:321-333
40. Saweirs W, Andrews D, Low-Beer T (1985) The double sugar test of intestinal permeability in the elderly. Age Ageing 14:312-315
41. Bjarnson I, MacPherson A, Hollander D (1995) Intestinal permeability: an overview. Gastroenterology 108:1566-1581
42. Meddings J (1997) Review article: Intestinal permeability in Crohn's disease. Aliment Pharm Ther 11(Suppl 3):47-53
43. Parikh-Patel A, Gold EB, Worman H, Krivy KE, Gershwin ME (2001) Risk factors for primary biliary cirrhosis in a cohort of patients from the United States. Hepatology 33:16-21
44. Tsuneyama K, Van De Water J, Yamazaki K, Suzuki K, Sato S, Takeda Y, Ruebner B, Yost BA, Nakanuma Y, Coppel RL, Gershwin ME (1997) Primary biliary cirrhosis an epithelitis: evidence of abnormal salivary gland immunohistochemistry. Autoimmunity 26:23-31
45. Tsuneyama K, Van de Water J, Nakanuma Y, Cha S, Ansari A, Coppel R, Gershwin ME (1994) Human combinatorial autoantibodies and mouse monoclonal antibodies to PDC-E2 produce abnormal apical staining of salivary glands in patients with coexistent primary biliary cirrhosis and Sjogren's syndrome. Hepatology 20(4, Pt 1):893-898
46. Nishio A, Keeffe EB, Gershwin ME (2002) Immunopathogenesis of primary biliary cirrhosis. Semin Liver Dis 22:291-302